US4876205A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Electrochemical assay for haemoglobin
Assignee: Genetics International Inc
•
Filing: 1987-08-12
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Granted: 1989-10-24
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Expires: 2007-08-12
Abstract
Abstract A method for the assay of haemoglobin in blood is provided in which the blood is contacted with a sufficient amount of a ferricyanide and the haemoglobin is electrochemically assayed by monitoring the current changes produced on reduction of the ferricyanide by the haemoglobin.
Inventors
- 👤 Monika J. Green
- 👤 Roger J. Lias
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 17:47
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/72; G01N33/721
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
49 words
A method for the assay of haemoglobin in blood comprising contacting the blood with a sufficient amount of a ferricyanide so that haemoglobin in the blood is reacted therewith and the haemoglobin is electrochemically assayed by monitoring the current change produced on reduction of the ferricyanide by the hemoglobin.
Claim 2
Independent Claim
49 words
A method for the assay of haemoglobin in blood comprising contacting the blood with a sufficient amount of a ferricyanide so that haemoglobin in the blood is reacted therewith and the haemoglobin is electrochemically assayed by monitoring the current change produced on reduction of the ferricyanide by the hemoglobin.
Claim 3
Dependent Claim
21 words
An assay method according to claim 1, wherein the blood is a sample of whole blood or a blood haemolysate sample.
Claim 4
Dependent Claim
25 words
An assay method according to claim 1, wherein the blood is provided as an unlysed sample, and the blood is treated with a haemolytic agent.
Claim 5
Dependent Claim
21 words
An assay method according to claim 1, wherein the current changes are monitored at a poised potential against a reference electrode.
Claim 6
Dependent Claim
22 words
An assay method according to claim 1, wherein the assay is performed using a dry strip sensor containing at least the ferricyanide.
Claim 7
Dependent Claim
25 words
An assay method according to claim 5, wherein the dry strip sensor is screen printed with a dry mixture containing finely divided ferricyanide, a surfactant,
Claim 8
Dependent Claim
16 words
An assay method according to claim 6 wherein said dry mixture further comprises a buffering agent.
Claim 9
Dependent Claim
23 words
An assay method according to claim 1, where said amount of ferricyanide is between 50 and 100 mg per ml of whole blood.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-10-23 | 1993-04-24 | 1993-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-10-23 | 1997-04-24 | 1997-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-10-23 | 2001-04-24 | 2001-10-24 | $7700.00 | Window Closed / Lapsed |