US4873265A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Anti-infective methods and compositions
Assignee: Thames Pharmacal Co Inc
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Filing: 1988-07-14
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Granted: 1989-10-10
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Expires: 2008-07-14
Abstract
Abstract Methods of providing local anti-infective treatment to a human or animal tissue area requiring such treatment comprise the application to the affected tissue area of an effetive amount of a composition containing from 0.5 to 5% by weight of selected antihistaminic agents in pharmaceutically acceptable topical vehicles including liquids, lotions, aerosols, creams, gels and ointments.
Inventors
- 👤 Steven T. Blackman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:51
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/495; A61K31/505; A61K31/519; A61K31/52
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
64 words
A method of providing local antimycotic treatment to a human or animal tissue area, in need thereof, comprising applying to said tissue area of an effective amount of a composition containing (a) from about 0.5 to about 5.0% by weight of an antihistaminic agent selected from the group consisting of ethanolamine derivatives and pharmaceutically acceptable salts thereof, and (b) a pharmaceutically acceptable topical vehicle.
Claim 2
Independent Claim
64 words
A method of providing local antimycotic treatment to a human or animal tissue area, in need thereof, comprising applying to said tissue area of an effective amount of a composition containing (a) from about 0.5 to about 5.0% by weight of an antihistaminic agent selected from the group consisting of ethanolamine derivatives and pharmaceutically acceptable salts thereof, and (b) a pharmaceutically acceptable topical vehicle.
Claim 3
Dependent Claim
22 words
A method according to claim 1 wherein said composition contains from about 1.0 to about 3.0% by weight of said antihistaminic agent.
Claim 4
Dependent Claim
24 words
A method according to claim 1 wherein said ethanolamine derivative is selected from the group consisting of diphenhydramine, dimenhydrinate and pharmaceutically acceptable salts thereof.
Claim 5
Dependent Claim
14 words
A method according to claim 3 wherein said vehicle ethanolamine derivative is diphenhydramine hydrochloride.
Claim 6
Dependent Claim
12 words
A method according to claim 1 wherein said vehicle is a gel.
Claim 7
Dependent Claim
12 words
A method according to claim 1 wherein said vehicle is a cream.
Claim 8
Dependent Claim
12 words
A method according to claim 1 wherein said vehicle is a lotion.
Claim 9
Dependent Claim
12 words
A method according to claim 1 wherein said vehicle is a liquid.
Claim 10
Dependent Claim
20 words
A method according to claim 8 wherein said liquid is an isotonic solution in which the antihistaminic agent is dissolved.
Claim 11
Dependent Claim
25 words
A method according to claim 1 wherein said effective amount is from 0.1 to 100 mg. of the composition per square centimeter of tissue area.
Claim 12
Dependent Claim
29 words
A method according to claim 1 wherein the composition is applied to the tissue area in a sufficient amount to provide a thin coating of composition over the area.
Claim 13
Dependent Claim
19 words
A method according to claim 1 wherein said composition is applied to the tissue area from 1-5 times daily.
Claim 14
Dependent Claim
24 words
A method according to claim 1 wherein said tissue area is an area of the skin, vagina, perianal area, nasal passages, throat or eyes.
Claim 15
Dependent Claim
22 words
A method according to claim 1 wherein said topical vehicle is selected from the group consisting of liquids, lotions, creams, and gels.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-10-09 | 1993-04-10 | 1993-10-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-10-09 | 1997-04-10 | 1997-10-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-10-09 | 2001-04-10 | 2001-10-10 | $7700.00 | Window Closed / Lapsed |