US4867905A
Expired / Lapsed
US
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Composition for liquid scintillation counting
Assignee: Beckman Coulter Inc
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Filing: 1988-02-26
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Granted: 1989-09-19
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Expires: 2008-02-26
Abstract
Abstract A liquid scintillation solution consisting of a fluor and a select solvent is presented, said solvent having the generic formula <IMAGE> where R1, R2, and R3 are either a methyl group or a hydrogen atom.
Inventors
- 👤 Stephen W. Wunderly
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 12:07
CPC Classifications
G; G01; G01T; G01T1/00; G01T1/16; G01T1/20; G01T1/204; G01T1/2042; C; C09; C09K; C09K11/00; C09K11/06
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
73 words
A liquid scintillation solution composition in which a radioactively labeled sample is mixed to obtain a scintillation phenomenon by which the sample is analyzed, comprising a mixture of a fluor compound and a solvent compound, liquid at 20° C. in its pure state, selected from a group having the chemical formula wherein R 1 is a methyl group and R 2 and R 3 are each a hydrogen atom or a methyl group.
Claim 2
Dependent Claim
73 words
A liquid scintillation solution composition in which a radioactively labeled sample is mixed to obtain a scintillation phenomenon by which the sample is analyzed, comprising a mixture of a fluor compound and a solvent compound, liquid at 20° C. in its pure state, selected from a group having the chemical formula wherein R 1 is a methyl group and R 2 and R 3 are each a hydrogen atom or a methyl group.
Claim 3
Dependent Claim
18 words
A liquid scintillation solution as described in claim 1 wherein said fluor compound is dissolved in said solvent.
Claim 4
Dependent Claim
14 words
A liquid scintillation solution as described in claim 1 additionally comprising an emulsifying agent.
Claim 5
Dependent Claim
15 words
A liquid scintillation solution as described in claim 1 additionally comprising a secondary flour compound.
Claim 6
Dependent Claim
22 words
A liquid scintillation solution as described in claim 1 wherein said fluor is selected from the group consisting of oxazoles or oxadiazoles.
Claim 7
Dependent Claim
23 words
A liquid scintillation solution as described in claim 4 wherein said secondary fluor is selected from the group consisting of oxazoles or oxadiazoles.
Claim 8
Dependent Claim
31 words
A liquid scintillation solution as described in claim 3 wherein said emulsifying agent is selected from the group consisting of Triton® ompounds or nonylphenyl polyethylene glycol ether compounds and polyethoxylated surfactants.
Claim 9
Dependent Claim
17 words
A liquid scintillation solution as described in claim 1 wherein said solvent has the chemical formula ##STR19##
Claim 10
Dependent Claim
17 words
A liquid scintillation solution as described in claim 1 wherein said solvent has the chemical formula ##STR20##
Claim 11
Dependent Claim
26 words
A liquid scintillation solution as described in claim 1 wherein said fluor is present in an amount of 1 to 20 grams per liter of solution.
Claim 12
Dependent Claim
26 words
A liquid scintillation solution as described in claim 4 wherein said secondary fluor is present in an amount of 0.05 to 5 grams per liter solution.
Claim 13
Dependent Claim
27 words
A liquid scintillation solution as described in claim 2 wherein said emulsifying agent is present in an amount of 100 to 500 grams per liter of solution.
Claim 14
Dependent Claim
66 words
A liquid scintillation solution composition in which a radioactively labeled sample is mixed to obtain a scintillation phenomenon by which the sample is analyzed, comprising a mixture of a fluor compound and a solvent compound selected from a group having the chemical formula ##STR21## wherein R 1 is a methyl group and R 2 and R 3 are each a hydrogen atom or a methyl group.
Claim 15
Dependent Claim
66 words
A liquid scintillation solution composition in which a radioactively labeled sample is mixed to obtain a scintillation phenomenon by which the sample is analyzed, comprising a mixture of a fluor compound and a solvent compound selected from a group having the chemical formula ##STR21## wherein R 1 is a methyl group and R 2 and R 3 are each a hydrogen atom or a methyl group.
Claim 16
Dependent Claim
78 words
A process of making a liquid scintillation solution composition in which a radioactively labeled sample can be mixed to obtain a scintillation phenomenon by which the sample can be analyzed comprising mixing a select amount of a solvent compound, liquid at 20° C. in its pue state, selected from a group having the chemical formula ##STR22## wherein R 1 is a methyl group and R 2 and R 3 are each a hydrogen atom or a methyl group.
Claim 17
Dependent Claim
78 words
A process of making a liquid scintillation solution composition in which a radioactively labeled sample can be mixed to obtain a scintillation phenomenon by which the sample can be analyzed comprising mixing a select amount of a solvent compound, liquid at 20° C. in its pue state, selected from a group having the chemical formula ##STR22## wherein R 1 is a methyl group and R 2 and R 3 are each a hydrogen atom or a methyl group.
Claim 18
Dependent Claim
21 words
A process as described in claim 14 wherein a secondary fluor is also mixed with the solvent and the primary fluor.
Claim 19
Dependent Claim
29 words
A process as described in claim 14 wherein 3-10 grams of primary fluor is mixed in an amount of the solvent to yield a solution volume of one liter.
Claim 20
Dependent Claim
35 words
A process as described in claim 14 wherein 3-10 grams of primary fluor and 0.10-1.0 grams of secondary fluor are mixed in an amount of the solvent to yield a solution volume of one liter.
Claim 21
Dependent Claim
20 words
A process as described in claim 14 wherein an emlsifying agent is also mixed with the solvent and primary fluor.
Claim 22
Dependent Claim
22 words
A process as described in claim 15 wherein an emulsifying agent is also mixed with the solvent. primary fluor and secondary fluor.
Claim 23
Dependent Claim
12 words
A process as described in claim 1 wherein said solvent is 1-phenyl-1-xylylethane.
Claim 24
Dependent Claim
13 words
A process as described in claim 20 wherein said primary fluor is PPO.
Claim 25
Dependent Claim
12 words
A process as described in claim 1 wherein said solvent is 1,1-dixylylethane
Claim 26
Dependent Claim
13 words
A process as described in claim 24 wherein said primary fluor is PPO.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-09-18 | 1993-03-20 | 1993-09-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-09-18 | 1997-03-20 | 1997-09-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-09-18 | 2001-03-20 | 2001-09-19 | $7700.00 | Window Closed / Lapsed |