US4866051A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Micronised beclomethasone dipropionate monohydrate compositions and methods of use
Assignee: Glaxo Group Ltd
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Filing: 1985-01-30
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Granted: 1989-09-12
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Expires: 2005-01-30
Abstract
Abstract Beclomethasone dipropionate in the form of its micronised monohydrate substantially free from water other than water of crystallisation. Pharmaceutical compositions containing the compound are also described. The compositions may be in the form of powder inhalation cartridges especially suitable for the treatment and/or prophylaxis of asthma.
Inventors
- 👤 John H. Hunt
- 👤 John M. Padfield
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 01:23
CPC Classifications
C; C07; C07J; C07J5/00; A; A61; A61K; A61K9/00; A61K9/0012; A61K9/007; A61K9/0073; A61K9/0075; A61K31/00; A61K31/56; A61K31/57; A61K9/14; A61K9/141; A61K9/145; A61P; A61P11/00; C07J5/0046; C07J5/0061; C07J5/0069; C07J5/0076
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
23 words
A pharmaceutical dry powder composition comprising micronised beclomethasone dipropionate monohydrate in association with at least one pharmaceutically acceptable dry powder carrier or excipient.
Claim 2
Dependent Claim
23 words
A pharmaceutical dry powder composition comprising micronised beclomethasone dipropionate monohydrate in association with at least one pharmaceutically acceptable dry powder carrier or excipient.
Claim 3
Dependent Claim
26 words
A composition according to claim 1 wherein at least 90% by weight of the micronised beclomethasone dipropionate monohydrate has an effective particle size below 10 μm.
Claim 4
Dependent Claim
28 words
A composition according to claim 2 wherein at least 90% by weight of the micronised beclomethasone dipropionate monohydrate has an effective particle size between 2 to 5 μm.
Claim 5
Dependent Claim
32 words
A composition according to claim 1 in the form of a dosage unit comprising a powder inhalation cartridge containing beclomethasone diproprionate monohydrate equivalent to from 10 to 1000 μg of beclomethasone dipropionate.
Claim 6
Dependent Claim
24 words
A composition according to claim 4 wherein the dosage unit contains beclomethasone dipropionate monohydrate equivalent to from 50 to 500 μg of beclomethasone dipropionate.
Claim 7
Dependent Claim
22 words
A composition according to claim 1 additionally containing at least one compound selected from the group consisting of salbutamol and sodium cromoglycate.
Claim 8
Dependent Claim
15 words
A pharamaceutical composition as claimed in claim 1 in association with a powder inhalation device.
Claim 9
Dependent Claim
13 words
A powder inhalation device containing a pharmaceutical composition as defined in claim 1.
Claim 10
Independent Claim
32 words
A method of treating bronchial conditions in a subject which comprises administering to said subject by inhalation techniques an effective amount of micronised beclomethasone dipropionate monohydrate in a pharmaceutical dry powder composition.
Claim 11
Independent Claim
32 words
A method of treating bronchial conditions in a subject which comprises administering to said subject by inhalation techniques an effective amount of micronised beclomethasone dipropionate monohydrate in a pharmaceutical dry powder composition.
References Cited (Backward Citations)
GB1047519A
Cited
US4364923A
Cited
GB1511820A
Cited
US4347236A
Cited
PT71309A
Cited
US4370322A
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US4391755A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-09-11 | 1993-03-13 | 1993-09-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-09-11 | 1997-03-13 | 1997-09-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-09-11 | 2001-03-13 | 2001-09-12 | $7700.00 | Window Closed / Lapsed |