US4865986A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Temperature control apparatus
Assignee: COY Corp A MI CORP
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Filing: 1988-10-06
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Granted: 1989-09-12
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Expires: 2008-10-06
Abstract
Abstract Apparatus is disclosed for controlling the heating and cooling of a plurality of upright containers containing a mixture used for performing gene amplification. The apparatus includes a support rack comprising aluminum blocks which is partially submerged in a thermally conductive fluid such that at least the lower portions of the containers are submerged in the fluid with the upper portions engaging the aluminum blocks for efficient heat transfer. Heaters are disposed within the aluminum block for heating the block and a plurality of thermoelectric cooling cells are used to cool the block. A programmable microprocessor is used for controlling the heating and cooling cycles, thereby allowing repetitive heating and cooling of the mixture to produce the copies of the genetic material sought to be copied. A cam separates the support rack from the cooling cells during the heating portion of the process.
Inventors
- 👤 Richard A. Coy
- 👤 Roy A. Waycaster
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 05:12
CPC Classifications
F; F25; F25B; F25B21/00; F25B21/02; B; B01; B01L; B01L7/00; B01L7/52
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
183 words
Apparatus for selectively heating and cooling a plurality of upright containers and their contents comprising: a metal heating block with vertical cavities therethrough for supporting said upright containers; a container for holding a quantity of thermally conductive fluid and for reception of said heating block within said fluid container with a portion of said upright containers in contact with the fluid; means for heating the metal heating block and the fluid, said heating means being disposed within said heating block between said vertical cavities; a metal cooling block below the fluid container and in vertical surface to surface engagement with said fluid container; thermoelectric cooling means beneath said cooling block and engaging said cooling block for cooling said heating block and fluid; temperature monitoring means within said heating block; and means selectively operative to provide alternatively for vertical separation of the fluid container and cooling block and vertical surface to surface engagement to enable heating of the contents of the upright containers rapidly and cooling of the contents of the upright containers rapidly while maintaining precise temperature conditions for precise periods of time.
Claim 2
Dependent Claim
183 words
Apparatus for selectively heating and cooling a plurality of upright containers and their contents comprising: a metal heating block with vertical cavities therethrough for supporting said upright containers; a container for holding a quantity of thermally conductive fluid and for reception of said heating block within said fluid container with a portion of said upright containers in contact with the fluid; means for heating the metal heating block and the fluid, said heating means being disposed within said heating block between said vertical cavities; a metal cooling block below the fluid container and in vertical surface to surface engagement with said fluid container; thermoelectric cooling means beneath said cooling block and engaging said cooling block for cooling said heating block and fluid; temperature monitoring means within said heating block; and means selectively operative to provide alternatively for vertical separation of the fluid container and cooling block and vertical surface to surface engagement to enable heating of the contents of the upright containers rapidly and cooling of the contents of the upright containers rapidly while maintaining precise temperature conditions for precise periods of time.
Claim 3
Dependent Claim
14 words
The apparatus of claim 1 wherein said selectively operable means includes an electric motor.
Claim 4
Dependent Claim
68 words
The apparatus of claim 2 wherein said selectively operable means includes cam means disposed between said fluid container and said cooling block, said cam means rotatable from an engagement position wherein said fluid container and cooling block are in surface to surface engagement to a separation position wherein said cam means separates said fluid container from said cooling block, said cam means being rotatable by said electric motor.
Claim 5
Dependent Claim
49 words
The apparatus of claim 3 wherein said cam means includes an elongated flat plate having a greater width than thickness, said plate extending between the fluid container and cooling block and positioned within a longitudinal groove in the top of said cooling block and bottom of said fluid container.
Claim 6
Dependent Claim
22 words
The apparatus of claim 2 wherein said selectively operable means includes floating mount means for attaching said electric motor and cam means.
Claim 7
Dependent Claim
14 words
The apparatus of claim 1 wherein said heating means includes an electrical resistance heater.
Claim 8
Dependent Claim
13 words
The apparatus of claim 1 wherein said thermoelectric cooling means includes peltier cells.
Claim 9
Dependent Claim
17 words
The apparatus of claim 1 further comprising control means for selectively activating said heating and cooling means.
Claim 10
Independent Claim
200 words
An apparatus for selectively heating and cooling a plurality of upright containers and the contents thereof, comprising: a support rack having a plurality of metal blocks in a side-by-side relationship, each of said blocks having a plurality of vertical apertures therethrough for supporting said upright containers; a container for holding a quantity of thermally conductive fluid for submerging a portion of said upright containers therein by placing said rack in said fluid container; electric resistance heaters disposed between said metal blocks and engaging said blocks for heating said support rack and fluid and thereby heating said upright container; a cooling block beneath said fluid container, said cooling block engageble with the bottom of said container; a plurality of thermoelectric cooling cells beneath said cooling block and engaging said cooling block for cooling said cooling block, fluid container, support rack and fluid, thereby cooling said upright containers; a thermocouple disposed within said support rack for monitoring the temperature of said rack; control means for activating the heaters and cooling cells for alternating heating and cooling said upright containers; and means operatively associated with said fluid container and cooling block for selectively disengaging and engaging said fluid container and said cooling block.
Claim 11
Independent Claim
200 words
An apparatus for selectively heating and cooling a plurality of upright containers and the contents thereof, comprising: a support rack having a plurality of metal blocks in a side-by-side relationship, each of said blocks having a plurality of vertical apertures therethrough for supporting said upright containers; a container for holding a quantity of thermally conductive fluid for submerging a portion of said upright containers therein by placing said rack in said fluid container; electric resistance heaters disposed between said metal blocks and engaging said blocks for heating said support rack and fluid and thereby heating said upright container; a cooling block beneath said fluid container, said cooling block engageble with the bottom of said container; a plurality of thermoelectric cooling cells beneath said cooling block and engaging said cooling block for cooling said cooling block, fluid container, support rack and fluid, thereby cooling said upright containers; a thermocouple disposed within said support rack for monitoring the temperature of said rack; control means for activating the heaters and cooling cells for alternating heating and cooling said upright containers; and means operatively associated with said fluid container and cooling block for selectively disengaging and engaging said fluid container and said cooling block.
Claim 12
Dependent Claim
60 words
The apparatus of claim 9 wherein said disengaging and engaging means includes cam means disposed between said fluid container and said cooling block, said cam means rotatable from an engagement position wherein said fluid container and cooling block are in surface to surface engagement to a separation position wherein said cam means separates said fluid container from said cooling block.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-09-11 | 1993-03-13 | 1993-09-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-09-11 | 1997-03-13 | 1997-09-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-09-11 | 2001-03-13 | 2001-09-12 | $7700.00 | Window Closed / Lapsed |