US4855141A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device comprising means for protecting and dispensing fluid sensitive medicament
Assignee: Alza Corp
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Filing: 1988-03-25
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Granted: 1989-08-08
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Expires: 2008-03-25
Abstract
Abstract A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
Inventors
- 👤 James B. Eckenhoff
- 👤 Judy A. Magruder
- 👤 Richard Cortese
- 👤 John R. Peery
- 👤 Jeremy C. Wright
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 05:28
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/27
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
80 words
A device for delivering porcine somatotropin to a pig, the device comprising: (a) a wall that surrounds; (b) an internal space; (c) means in the wall for connecting the exterior of the device with the internal space; (d) a composition in the space comprising porcine somatotropin and a pharmaceutically acceptable polyol and (e) a composition in the space comprising means for diminishing the volume occupied by the composition comprising the porcine somatotropin, thereby delivering the porcine somatotropin to the pig.
Claim 2
Independent Claim
80 words
A device for delivering porcine somatotropin to a pig, the device comprising: (a) a wall that surrounds; (b) an internal space; (c) means in the wall for connecting the exterior of the device with the internal space; (d) a composition in the space comprising porcine somatotropin and a pharmaceutically acceptable polyol and (e) a composition in the space comprising means for diminishing the volume occupied by the composition comprising the porcine somatotropin, thereby delivering the porcine somatotropin to the pig.
Claim 3
Independent Claim
97 words
A device for delivering a somatotropin to livestock, the device comprising: (a) a wall; (b) a lumen defined by the wall; (c) means in the wall for connecting the exterior with the interior of the device; (d) a composition in the lumen comprising a somatotropin and a member selected from the group consisting of 1,5-pentylene glycol, 1,6-hexylene glycol, 1,7-heptylene glycol, 1,9-nonylene glycol, 1,2-dimethyl-1,6-hexylene glycol, 1,2,3-propanetriol, 1,2,5-pentanetriol, 1,3,5-pentanetriol, 1,2,4-butanetriol and dipentaerythriol; and; (e) a composition in the lumen comprising means for diminishing the volume occupied by the composition comprising the somatotropin for delivering the somatotropin to the livestock.
Claim 4
Independent Claim
97 words
A device for delivering a somatotropin to livestock, the device comprising: (a) a wall; (b) a lumen defined by the wall; (c) means in the wall for connecting the exterior with the interior of the device; (d) a composition in the lumen comprising a somatotropin and a member selected from the group consisting of 1,5-pentylene glycol, 1,6-hexylene glycol, 1,7-heptylene glycol, 1,9-nonylene glycol, 1,2-dimethyl-1,6-hexylene glycol, 1,2,3-propanetriol, 1,2,5-pentanetriol, 1,3,5-pentanetriol, 1,2,4-butanetriol and dipentaerythriol; and; (e) a composition in the lumen comprising means for diminishing the volume occupied by the composition comprising the somatotropin for delivering the somatotropin to the livestock.
Claim 5
Independent Claim
116 words
A device for delivering in vivo a somatotropin to an animal, the device comprising: (a) a wall; (b) a lumen defined by the wall; (c) means in the device for connecting the exterior with the interior of the device; (d) a composition in the lumen comprising a somatotropin and pharmaceutically acceptable member selected from the group consisting of a diol, a triol, a polyol and a polyhydric alcohol; (e) a composition in the lumen comprising means for diminishing the volume occupied by the composition comprising the somatotropin for delivering the somatotropin to the animal; and, (f) composition means between (d) and (e) for maximizing the delivery of somatotropin from the device to the animal over time.
Claim 6
Independent Claim
116 words
A device for delivering in vivo a somatotropin to an animal, the device comprising: (a) a wall; (b) a lumen defined by the wall; (c) means in the device for connecting the exterior with the interior of the device; (d) a composition in the lumen comprising a somatotropin and pharmaceutically acceptable member selected from the group consisting of a diol, a triol, a polyol and a polyhydric alcohol; (e) a composition in the lumen comprising means for diminishing the volume occupied by the composition comprising the somatotropin for delivering the somatotropin to the animal; and, (f) composition means between (d) and (e) for maximizing the delivery of somatotropin from the device to the animal over time.
Claim 7
Independent Claim
108 words
A device for delivering a beneficial agent to an animal, wherein the device comprises: (a) a wall; (b) an internal lumen defined by the wall; (c) exit means in the wall for connecting the exterior with the interior of the device; (d) a beneficial agent composition in the lumen comprising a somatotropin and a pharmaceutically acceptable carrier; (e) driving means in the lumen for decreasing the space occupied by the beneficial agent composition; and, (f) means between the beneficial agent composition and the driving means for insuring the force generated by the driving means is applied against the beneficial agent composition for delivering the somatotropin to the animal.
Claim 8
Independent Claim
108 words
A device for delivering a beneficial agent to an animal, wherein the device comprises: (a) a wall; (b) an internal lumen defined by the wall; (c) exit means in the wall for connecting the exterior with the interior of the device; (d) a beneficial agent composition in the lumen comprising a somatotropin and a pharmaceutically acceptable carrier; (e) driving means in the lumen for decreasing the space occupied by the beneficial agent composition; and, (f) means between the beneficial agent composition and the driving means for insuring the force generated by the driving means is applied against the beneficial agent composition for delivering the somatotropin to the animal.
Claim 9
Independent Claim
69 words
A device for delivering somatotropin to an environment of use, wherein the device comprises: (a) a wall; (b) an internal lumen defined by the wall; (c) exit means for connecting the exterior and the interior of the device; (d) a somatotropin in the lumen; (e) means for protecting the somatotropin from the environment of use; and, (f) means in the lumen for occupying the space occupied by the somatotropin.
Claim 10
Independent Claim
69 words
A device for delivering somatotropin to an environment of use, wherein the device comprises: (a) a wall; (b) an internal lumen defined by the wall; (c) exit means for connecting the exterior and the interior of the device; (d) a somatotropin in the lumen; (e) means for protecting the somatotropin from the environment of use; and, (f) means in the lumen for occupying the space occupied by the somatotropin.
Claim 11
Dependent Claim
29 words
The device for delivering somatotropin to an environment of use according to claim 5, wherein the device comprises means for protecting the somatotropin from an aqueous environment of use.
Claim 12
Dependent Claim
34 words
The device for delivering somatotropin to an environment of use according to claim 5, wherein the device comprises means for protecting the somatotropin by restricting the passage of an exterior fluid into the device.
Claim 13
Dependent Claim
36 words
The device for delivering somatotropin to an environment of use according to claim 5, wherein the device comprises a composition substantially impermeable to the passage of fluid between the somatotropin and the means for occupying space.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-08-07 | 1993-02-06 | 1993-08-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-08-07 | 1997-02-06 | 1997-08-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-08-07 | 2001-02-06 | 2001-08-08 | $7700.00 | Window Closed / Lapsed |