US4853546A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Automatic radioisotope filling apparatus
Assignee: Ube Corp
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Filing: 1987-09-16
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Granted: 1989-08-01
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Expires: 2007-09-16
Abstract
Abstract An automatic radioisotope filling apparatus which includes a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution and a plurality of label vials containing a drug into which a predetermined amount of the radioisotope solution or the physiological saline solution is to be filled automatically. A required amount of the radioisotope solution or the physiological saline solution is automatically metered and automatically filled into each label vial and consequently the radiation exposure of the operator of the apparatus is minimized.
Inventors
- 👤 Shuzo Abe
- 👤 Satoshi Matsunami
- 👤 Sunao Nagamatsu
- 👤 Masaaki Tanaka
- 👤 Masao Matsuno
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 15:21
CPC Classifications
G; G01; G01T; G01T7/00; G01T7/02; G01N; G01N1/00; G01N1/28; G01N1/38; G21; G21G; G21G4/00; G21G4/02
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
154 words
An automatic radioisotope filling apparatus which comprises: a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution, a plurality of label vials containing a drug into which a predetermined amount of the radioisotope solution or the physiological saline solution is to be provided from the radioisotope vial and the saline vial, a container for said plurality of label vials, conduit means for selectively transferring the radioisotope solution and the physiological saline solution from the radioisotope vial and the saline vial to each of the pluraltiy of label vials, and means for selectively and automatically controlling the flow of said radioisotope solution and the physiological saline solution through said conduit means, whereby a required amount of the radioisotope solution and the physiological saline solution for each of the label vials may be automatically withdrawn from the radioisotope vial and the saline vial and provided to each of the label vials.
Claim 2
Dependent Claim
154 words
An automatic radioisotope filling apparatus which comprises: a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution, a plurality of label vials containing a drug into which a predetermined amount of the radioisotope solution or the physiological saline solution is to be provided from the radioisotope vial and the saline vial, a container for said plurality of label vials, conduit means for selectively transferring the radioisotope solution and the physiological saline solution from the radioisotope vial and the saline vial to each of the pluraltiy of label vials, and means for selectively and automatically controlling the flow of said radioisotope solution and the physiological saline solution through said conduit means, whereby a required amount of the radioisotope solution and the physiological saline solution for each of the label vials may be automatically withdrawn from the radioisotope vial and the saline vial and provided to each of the label vials.
Claim 3
Dependent Claim
24 words
An automatic radioisotope filling apparatus according to claim 1 wherein said container for said plurality of label vials is provided with a stirring mechanism.
Claim 4
Dependent Claim
47 words
An automatic radioisotope filling apparatus according to claim 1, wherein said conduit means includes a distributor for receiving said radioisotope solution and said physiological saline solution and directing the flow of said radioisotope solution and said physiological saline solution to each of said plurality of label vials.
Claim 5
Dependent Claim
185 words
An automatic radioisotope filling apparatus which comprises: a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution, a plurality of label vials containing a drug into which a predetermined amount of the radioisotope solution or the physiological saline solution is to be provided from the radioisotope vial and the saline vial, a dilution vial, conduit means including said dilution vial for selectively transferring the radioisotope solution and the physiological saline solution from the radioisotope vial and the saline vial to each of the plurality of label vials, means for selectively and automatically controlling the flow of said radioisotope solution and the physiological saline solution through said conduit means including, metering means for withdrawing and transferring a measured volume of the radioisotope solution from said radioisotope vial to said dilution vial, a radiation detector for measuring the radioactive intensity of the radioisotope solution transferred to the dilution vial, and means for calculating the specific radioactivity of the radioisotope solution transferred to the dilution vial based on the measured volume and radioactive intensity of the radioisotope solution transferred to the dilution vial.
Claim 6
Dependent Claim
185 words
An automatic radioisotope filling apparatus which comprises: a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution, a plurality of label vials containing a drug into which a predetermined amount of the radioisotope solution or the physiological saline solution is to be provided from the radioisotope vial and the saline vial, a dilution vial, conduit means including said dilution vial for selectively transferring the radioisotope solution and the physiological saline solution from the radioisotope vial and the saline vial to each of the plurality of label vials, means for selectively and automatically controlling the flow of said radioisotope solution and the physiological saline solution through said conduit means including, metering means for withdrawing and transferring a measured volume of the radioisotope solution from said radioisotope vial to said dilution vial, a radiation detector for measuring the radioactive intensity of the radioisotope solution transferred to the dilution vial, and means for calculating the specific radioactivity of the radioisotope solution transferred to the dilution vial based on the measured volume and radioactive intensity of the radioisotope solution transferred to the dilution vial.
Claim 7
Independent Claim
220 words
An apparatus for automatically providing a plurality of label vials containing a radioactive solution of a specific radioactivity comprising: a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution, a plurality of label vials containing a drug into which said radioisotope solution is to be provided, a dilution vial, conduit means for selectively transferring the radioisotope solution and the physiological saline solution from the radioisotope vial and the saline vial to the dilution vial, metering means for withdrawing and transferring a measured volume of the radioisotope solution from said radioisotope vial to said dilution vial, a radiation detector for measuring the radioactive intensity of the radioisotope solution transferred to the dilution vial, and means for calculating the specific radioactivity of the radioisotope solution transferred to the dilution vial based on the measured volume and radioactive intensity of the radioisotope solution transferred to the dilution vial and determining a volume of the physiological saline solution required to adjust the radioactive intensity of the radioisotope solution in the dilution vial to a specific radioactivity, metering means responsive to said calculating means for withdrawing and transferring said required volume of the physiological saline solution to said dilution vial, and means for selectively transferring the radioisotope solution and physiological saline solution from said dilution vial to said label vials.
Claim 8
Independent Claim
220 words
An apparatus for automatically providing a plurality of label vials containing a radioactive solution of a specific radioactivity comprising: a radioisotope vial containing a radioisotope solution, a saline vial containing a physiological saline solution, a plurality of label vials containing a drug into which said radioisotope solution is to be provided, a dilution vial, conduit means for selectively transferring the radioisotope solution and the physiological saline solution from the radioisotope vial and the saline vial to the dilution vial, metering means for withdrawing and transferring a measured volume of the radioisotope solution from said radioisotope vial to said dilution vial, a radiation detector for measuring the radioactive intensity of the radioisotope solution transferred to the dilution vial, and means for calculating the specific radioactivity of the radioisotope solution transferred to the dilution vial based on the measured volume and radioactive intensity of the radioisotope solution transferred to the dilution vial and determining a volume of the physiological saline solution required to adjust the radioactive intensity of the radioisotope solution in the dilution vial to a specific radioactivity, metering means responsive to said calculating means for withdrawing and transferring said required volume of the physiological saline solution to said dilution vial, and means for selectively transferring the radioisotope solution and physiological saline solution from said dilution vial to said label vials.
Claim 9
Dependent Claim
43 words
An automatic radioisotope filling apparatus according to claim 4 or 5, wherein said conduit means includes a plurality of tubes and further comprising a detector for fluid discontinuity provided in the middle of a tube connecting the radioisotope vial and the metering means.
Claim 10
Dependent Claim
41 words
An automatic radioisotope filling apparatus according to claim 4 or 5, wherein said conduit means includes a plurality of tubes and further comprising a pressure detector provided in the middle of a tube connecting the metering means and the dilution vial.
Claim 11
Dependent Claim
56 words
An automatic radioisotope filling apparatus according to claim 4 or 5, wherein said conduit means includes a plurality of tubes for transferring the radioisotope solution and the physiological solution and for venting gases during transfer of said solutions and said plurality of tubes are fixed for support on a sheet which provides an integral flow unit.
Claim 12
Dependent Claim
29 words
An automatic radioisotope filling apparatus according to claim 4 or 5, wherein the label vials are accomodated in a plurality of radiation-shielding lead containers fixed to a portable cartridge.
Claim 13
Dependent Claim
55 words
An automatic radioisotope filling apparatus according to claim 4 or 5, wherein a needle is inserted into each label vial for supplying or discharging a gas into or from the label vial, a tube is connected to the needle at one end, and the other end of the tube is connected to a buffer container.
Claim 14
Dependent Claim
21 words
An automatic radioisotope filling apparatus according to claim 4 or 5, wherein the label vials are provided with a stirring mechanism.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-31 | 1993-01-30 | 1993-08-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-31 | 1997-01-30 | 1997-08-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-31 | 2001-01-30 | 2001-08-01 | $7700.00 | Window Closed / Lapsed |