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US4852573A Expired / Lapsed US ⏱️ 0.0 years remaining

Implantable neural electrode

Assignee: Individual
•
Filing: 1987-12-04
•
Granted: 1989-08-01
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Expires: 2007-12-04
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Abstract

Abstract An electrode implantable in the brain or other area of neural activity to provide long term recording of electrical signals. The electrode comprises (a) a conducting wire, being insulated along its length except for a pre-determined area, for conducting an electrical signal to or from the body from or to an extracorporeal transmitter or receiver; and (b) an open hollow insulating structure surrounding at least a portion of an exposed portion of the conducting wire for electrically isolating signal within the structure from that outside the structure. A method is disclosed for implanting the electrode. Also disclosed is the use of a viable nerve segment dissected from a remote part of the body, such as the sciatic nerve, to serve as an anchor for neurite growth from the brain into the insulator and in proximity to or contacting the exposed end of the wire.

Inventors

  • 👤 Philip R. Kennedy

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 18:16
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/0002; A61B5/0004; A61B5/0006; A61B5/24

Claims Analysis

Total Claims: 26
Claim 1
Independent Claim 158 words
A neural electrode capable of being implanted in operative relation with neural structure in a body, comprising: a flexible electrical conductor, insulated except for a predetermined area, for conducting an electrical signal between a predetermined location within said body and predetermined point outside said body; a biologically inert electrically insulative structure defining an interior cavity and having at least one opening into the cavity, said insulative structure surrounding at least said predetermined area of said conductor and electrically substantially isolating said conductor from points other than said predetermined within said body; and a nerve segment separate from the neural structure, said nerve segment being disposed in electroconductive relation with the predetermined area and being at least partially within the insulative structure so as to facilitate the growth, within said insulative structure, of neurites associated with the neural structure, whereby the electrical conductor is capable of receiving electrical signals from the body or transmitting electrical signals to the body.
Claim 2
Dependent Claim 158 words
A neural electrode capable of being implanted in operative relation with neural structure in a body, comprising: a flexible electrical conductor, insulated except for a predetermined area, for conducting an electrical signal between a predetermined location within said body and predetermined point outside said body; a biologically inert electrically insulative structure defining an interior cavity and having at least one opening into the cavity, said insulative structure surrounding at least said predetermined area of said conductor and electrically substantially isolating said conductor from points other than said predetermined within said body; and a nerve segment separate from the neural structure, said nerve segment being disposed in electroconductive relation with the predetermined area and being at least partially within the insulative structure so as to facilitate the growth, within said insulative structure, of neurites associated with the neural structure, whereby the electrical conductor is capable of receiving electrical signals from the body or transmitting electrical signals to the body.
Claim 3
Dependent Claim 14 words
The electrode of claim 1, wherein said electrical conductor comprises a flexible implantable wire.
Claim 4
Dependent Claim 32 words
The electrode of claim 2, wherein said wire is formed into a serires of coils along a predetermined portion of its length for permitting flexion of said wire in response to movement.
Claim 5
Dependent Claim 24 words
The electrode 2, wherein said insulative structure comprises a hollow cone having a least one opening, and said electrical conductor extends into said opening.
Claim 6
Dependent Claim 24 words
The electrode 2, wherein said insulative structure comprises a hollow cone having a least one opening, and said electrical conductor extends into said opening.
Claim 7
Dependent Claim 27 words
The electrode of claim 1, wherein said insulative structure is a hollow tubular element having at least one opening, and said electrical conductor extends into said opening.
Claim 8
Dependent Claim 19 words
The electrode of claim 1, wherein said electrical conductor is secured to an inner wall of said insulative structure.
Claim 9
Independent Claim 167 words
A method for receiving or transmitting electrical signals relative to neural structure of a body, comprising: (a) implanting an electrode within said body, said electrode prepared by the steps comprising: (i) preparing a conducting means insulated except for a predetermined area and operative for conducting an electrical signal between a predetermined location within said body and a predetermined point outside said body; (ii) surrounding at least said predetermined are of said conducting means with an insulating means for electrically isolating said conducting means from points other than said predetermined location within said body; and (iii) placing a nerve segment separate from the neural structure in electroconductive relation with the predetermined area and at least partially within the insulating means, so as to facilitate the growth of neurites within the insulating means: and (b) receiving electrical signals from said body or transmitting electrical signals to said body by way of said electrode and said nerve segment,w which bridges said conducting means to at least one of said neurites.
Claim 10
Independent Claim 167 words
A method for receiving or transmitting electrical signals relative to neural structure of a body, comprising: (a) implanting an electrode within said body, said electrode prepared by the steps comprising: (i) preparing a conducting means insulated except for a predetermined area and operative for conducting an electrical signal between a predetermined location within said body and a predetermined point outside said body; (ii) surrounding at least said predetermined are of said conducting means with an insulating means for electrically isolating said conducting means from points other than said predetermined location within said body; and (iii) placing a nerve segment separate from the neural structure in electroconductive relation with the predetermined area and at least partially within the insulating means, so as to facilitate the growth of neurites within the insulating means: and (b) receiving electrical signals from said body or transmitting electrical signals to said body by way of said electrode and said nerve segment,w which bridges said conducting means to at least one of said neurites.
Claim 11
Dependent Claim 16 words
The method of claim 7, comprising the further step of adhering said electrode to said body.
Claim 12
Dependent Claim 37 words
The method of claim 7, comprising the further step of adhering said electrode is said body by adhering a predetermined portion of said conducting means to bone matter of the body by means of a biocompatible cement
Claim 13
Dependent Claim 25 words
The method of claim 9, wherein said cement is secured to said bone, in addition to adhesion, by a fastening means secured to said bone.
Claim 14
Dependent Claim 37 words
The method of claim 17, comprising the further steps of mounting a screw in said bone and extending partially out of said bone, and fastening said cement to said bone by the screw in addition to adhesion.
Claim 15
Dependent Claim 37 words
The method of claim 7, comprising the further steps of placing said nerve segment on said conducting means and allowing the nerve segment to dry thereon, so that the nerve segment thereby adheres to said conducting means.
Claim 16
Dependent Claim 31 words
The method of claim 7, wherein at least one of said neurites grows so as to contact said nerve segment, thereby producing a bioelectrical contact between said neurite and said electrode.
Claim 17
Dependent Claim 28 words
The method of claim 7, wherein said nerve segment is removed from said body before being placed in said electroconductive relation with the predetermined are of said conducting.
Claim 18
Dependent Claim 16 words
The method of claim 14, wherein said nerve segment comprises a portion of a sciatic nerve.
Claim 19
Dependent Claim 35 words
The method as in claim 7, comprising the further step of dissecting the nerve segment from a remote part of said body, prior to placing the nerve segment in electroconductive relation with the conducting means.
Claim 20
Independent Claim 195 words
A method for receiving or transmitting electrical signals from or to a body, comprising: (a) making an incision in said body; (b) placing an electrode in proximity to viable neurons, said electrode prepared by the steps comprising: (i) preparing a conducting means insulated except for a predetermined area for conducting an electrical signal between a predetermined location within said body and a predetermined point outside said body; (ii) surrounding at least said predetermined are of said conducting means with an insulating means for electrically isolating said conducting means from points other than said predetermined location within said body; and (iii) placing a nerve segment separate from the body in electroconductive relation with the predetermined location and at least partially within the insulating means, so as to facilitate the growth of neurites within the insulating means; and (c) securing said electrode in a biocompatible manner so as to favor the growing of neurites within said electrode; (d) closing said incision so that a portion of said electrode extends extracorporeally; and (e) using said extracorporeally extending portion of the electrode for receiving said electrical signals produced by said body or transmitting said electrical signals to said body.
Claim 21
Independent Claim 195 words
A method for receiving or transmitting electrical signals from or to a body, comprising: (a) making an incision in said body; (b) placing an electrode in proximity to viable neurons, said electrode prepared by the steps comprising: (i) preparing a conducting means insulated except for a predetermined area for conducting an electrical signal between a predetermined location within said body and a predetermined point outside said body; (ii) surrounding at least said predetermined are of said conducting means with an insulating means for electrically isolating said conducting means from points other than said predetermined location within said body; and (iii) placing a nerve segment separate from the body in electroconductive relation with the predetermined location and at least partially within the insulating means, so as to facilitate the growth of neurites within the insulating means; and (c) securing said electrode in a biocompatible manner so as to favor the growing of neurites within said electrode; (d) closing said incision so that a portion of said electrode extends extracorporeally; and (e) using said extracorporeally extending portion of the electrode for receiving said electrical signals produced by said body or transmitting said electrical signals to said body.
Claim 22
Dependent Claim 25 words
The method of claim 17, comprising the step of selecting said conducting means from the group consisting of a metallic and an essentially metallic material.
Claim 23
Dependent Claim 12 words
The method of claim 18, wherein said conducting means comprises gold wire.
Claim 24
Dependent Claim 119 words
A neural electrode capable of being implanted in a body, comprising: (a) signal generating means for generating signals in response to nerve fiber activity proximate thereto; (b) an insulative structure having at least one opening and an interior cavity having a nerve fiber segment separate from the body disposed therein in proximity to said signal generating means; (c) an electrical wire connected to said signal generating means for conducting said signals between said signal generating means within said body and a predetermined point outside said body; and (d) a portion of said signal generating means is in proximity to said nerve fiber segment within said insulative structure, so as to facilitate the growth of neurites within the insulative structure.
Claim 25
Dependent Claim 119 words
A neural electrode capable of being implanted in a body, comprising: (a) signal generating means for generating signals in response to nerve fiber activity proximate thereto; (b) an insulative structure having at least one opening and an interior cavity having a nerve fiber segment separate from the body disposed therein in proximity to said signal generating means; (c) an electrical wire connected to said signal generating means for conducting said signals between said signal generating means within said body and a predetermined point outside said body; and (d) a portion of said signal generating means is in proximity to said nerve fiber segment within said insulative structure, so as to facilitate the growth of neurites within the insulative structure.
Claim 26
Dependent Claim 20 words
The neural electrode of claim 20, further comprising a signal recording and generating means in communication with said electrical wire.

References Cited (Backward Citations)

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-07-31 1993-01-30 1993-08-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-07-31 1997-01-30 1997-08-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-07-31 2001-01-30 2001-08-01 $7700.00 Window Closed / Lapsed

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