US4849223A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antimicrobial compositions consisting of metallic silver combined with titanium oxide or tantalum oxide
Assignee: Johnson Matthey PLC
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Filing: 1985-12-30
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Granted: 1989-07-18
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Expires: 2005-12-30
Abstract
Abstract An antimicrobial composition which includes silver as the antimicrobial agent also includes a hydratable or hydrated oxide as a promoter to enhance the antimicrobial effect. Such compositions may be used to coat appliances such as catheters or may be incorporated in bone cements.
Inventors
- 👤 Allin S. Pratt
- 👤 Peter R. Smith
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-27 23:00
CPC Classifications
A; A61; A61L; A61L31/00; A61L31/14; A61L31/16; A01; A01N; A01N59/00; A01N59/16; A61L24/00; A61L24/001; A61L24/0015; A61L27/00; A61L27/50; A61L27/54; A61L29/00; A61L29/14; A61L29/16; A61L2300/00; A61L2300/10; A61L2300/102; A61L2300/104; A61L2300/40; A61L2300/404; A61L2300/80; A61L2300/802; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
62 words
An antimicrobial composition for use in contact with materials which cause or are susceptible to bacterial infection by body fluids or tissue, said composition comprising metallic silver as the antimicrobial agent together with an oxide component selected from the group consisting of titanium and tantalum oxides present in an amount effective to provide release of silver ions into surrounding tissue or fluid.
Claim 2
Dependent Claim
62 words
An antimicrobial composition for use in contact with materials which cause or are susceptible to bacterial infection by body fluids or tissue, said composition comprising metallic silver as the antimicrobial agent together with an oxide component selected from the group consisting of titanium and tantalum oxides present in an amount effective to provide release of silver ions into surrounding tissue or fluid.
Claim 3
Dependent Claim
17 words
An antimicrobial composition according to claim 1, in which the composition is dispersed in a polymeric material.
Claim 4
Dependent Claim
28 words
An antimicrobial composition according to claim 2, in which the composition constitutes from 1 to 75% by weight, based on the total of antimicrobial composition and cured polymer.
Claim 5
Dependent Claim
16 words
An antimicrobial composition according to in which the silver is deposited on particles of titanium dioxide.
Claim 6
Dependent Claim
16 words
An antimicrobial composition according to in which the silver is deposited on particles of titanium dioxide.
Claim 7
Dependent Claim
19 words
An antimicrobial composition according to claim 4, which the mean particle size of the oxide is below 5 microns.
Claim 8
Dependent Claim
25 words
An antimicrobial composition according to 5, in which the surface area of the oxide particles is between 1 and 100 m 2 g -1 inclusive.
Claim 9
Dependent Claim
25 words
An antimicrobial composition according to 5, in which the surface area of the oxide particles is between 1 and 100 m 2 g -1 inclusive.
Claim 10
Dependent Claim
21 words
A medical or other appliance, characterized in that it is coated or impregnated with an antimicrobial composition according to claim 1.
Claim 11
Dependent Claim
27 words
A bone cement mixture comprising an acrylic powder, an acrylic monomer and a filler, characterized in that the filler includes an antimicrobial composition according to claim 1.
Claim 12
Dependent Claim
43 words
In an antimicrobial composition comprising metallic silver as the antimicrobial agent and wherein the activity of said agent is undesirably affected in contact with body fluids, the improvement which comprises including in said composition titanium dioxide to enhance the activity of said agent.
Claim 13
Dependent Claim
43 words
In an antimicrobial composition comprising metallic silver as the antimicrobial agent and wherein the activity of said agent is undesirably affected in contact with body fluids, the improvement which comprises including in said composition titanium dioxide to enhance the activity of said agent.
Claim 14
Dependent Claim
65 words
In a method wherein metallic silver is used as an antimicrobial agent in the presence of fluids which tend to undesirably affect the antimicrobial activity of the silver, the improvement which comprises including titanium dioxide with the metallic silver to stabilize the activity of the silver against said fluids and to provide release of silver ions into the fluid to produce a sustained antimicrobial effect.
Claim 15
Dependent Claim
65 words
In a method wherein metallic silver is used as an antimicrobial agent in the presence of fluids which tend to undesirably affect the antimicrobial activity of the silver, the improvement which comprises including titanium dioxide with the metallic silver to stabilize the activity of the silver against said fluids and to provide release of silver ions into the fluid to produce a sustained antimicrobial effect.
Claim 16
Dependent Claim
16 words
A composition according to claim 1 including 110% silver, the balance consisting essentially of titanium dioxide.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-17 | 1993-01-16 | 1993-07-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-17 | 1997-01-16 | 1997-07-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-17 | 2001-01-16 | 2001-07-18 | $7700.00 | Window Closed / Lapsed |