US4846650A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Oral compositions and methods for reducing dental calculus
Assignee: Procter and Gamble Co
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Filing: 1987-08-17
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Granted: 1989-07-11
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Expires: 2007-08-17
Abstract
Abstract The present invention relates to oral compositions, such as dentrifices, toothpastes and mounthwashes, which provide an anticalculus benefit. These compositions comprise a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salts, along with a pharmaceutically-acceptable carrier. The present invention also relates to a method for inhibiting or reducing the development of dental calculus by contacting the oral cavity with a safe and effective amount of an anticalculus agent which is a polyepoxysuccinic acid, or its pharmaceutically-acceptable salt.
Inventors
- 👤 James J. Benedict
- 👤 Rodney D. Bush
- 👤 Richard J. Sunberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 01:25
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/72; A61K8/81; A61K8/8164; A61K8/30; A61K8/33; A61K8/36; A61K8/365; A61Q; A61Q11/00
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
73 words
A method of retarding dental calculus formation, which method comprises the step of contacting, by brushing or rinsing or masticating, the oral cavity and orgal surfaces with from about 0.01 grams to about 5 grams of an anticalculus agent which is a polyepoxysuccinic acid, or a pharmaceutically-accepted salt thereof, of the formula: ##STR3## wherein M is hydrogen or a pharmaceutically-acceptable cation, and n is an integer of from about 2 to about 25.
Claim 2
Independent Claim
73 words
A method of retarding dental calculus formation, which method comprises the step of contacting, by brushing or rinsing or masticating, the oral cavity and orgal surfaces with from about 0.01 grams to about 5 grams of an anticalculus agent which is a polyepoxysuccinic acid, or a pharmaceutically-accepted salt thereof, of the formula: ##STR3## wherein M is hydrogen or a pharmaceutically-acceptable cation, and n is an integer of from about 2 to about 25.
Claim 3
Dependent Claim
28 words
A method according to claim 1 wherein in the formula for the polyepoxysuccinic acid, or its pharmaceutically-acceptable salt, n is an integer from about 4 to about 10.
Claim 4
Dependent Claim
26 words
A method according to claim 2 wherein the amount of the anticalculus agent is within the range of from about 0.025 grams to about 1.0 grams.
Claim 5
Dependent Claim
22 words
A method according to claim 3 wherein the average molecular weight of the polyepoxysuccinic acid, or its pharmaceutically-acceptable salt, is about 650.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-10 | 1993-01-09 | 1993-07-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-10 | 1997-01-09 | 1997-07-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-10 | 2001-01-09 | 2001-07-11 | $7700.00 | Window Closed / Lapsed |