US4845128A
Expired / Lapsed
US
⏱️ 0.0 years remaining
N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
Assignee: Eli Lilly and Co
•
Filing: 1985-05-02
•
Granted: 1989-07-04
•
Expires: 2005-05-02
Abstract
Abstract This invention provides the use of certain benzenesulfonamide derivatives in the treatment of susceptible neoplasms in mammals. Also provided are certain novel benzenesulfonamide derivatives and their pharmaceutical formulations.
Inventors
- 👤 Richard W. Harper
- 👤 Gerald A. Poore
- 👤 Brent J. Rieder
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:50
CPC Classifications
C; C07; C07C; C07C303/00; C07C303/36; C07C311/00; C07C311/50; C07C311/52; C07C311/54; C07C311/57; C07C311/60; A; A61; A61P; A61P35/00; A61P35/02
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
36 words
A compound of the formula ##STR8## wherein: R 1 and R 3 are independently hydrogen, C 1 -C 3 alkyl, halo, or C 1 -C 3 alkoxy; and R 4 is hydrogen, halo, methyl, or trifluoromethyl.
Claim 2
Dependent Claim
36 words
A compound of the formula ##STR8## wherein: R 1 and R 3 are independently hydrogen, C 1 -C 3 alkyl, halo, or C 1 -C 3 alkoxy; and R 4 is hydrogen, halo, methyl, or trifluoromethyl.
Claim 3
Dependent Claim
8 words
The compound of claim 1 which is 4-methyl-N-([(4-trifluoromethylphenyl)amino]carbonyl)benzenesulfonamide.
Claim 4
Dependent Claim
8 words
The compound of claim 1 which is 4-methoxy-N-([(4-trifluoromethylphenyl)amino]carbonyl)benzenesulfonamide.
Claim 5
Dependent Claim
8 words
The compound of claim 1 which is 4-chloro-N-([(4-trifluoromethylphenyl)amino]carbonyl)benzenesulfonamide.
Claim 6
Dependent Claim
17 words
A pharmaceutical formulation which comprises a compound of claim 1 and a pharmaceutically acceptable carrier or diluent.
Claim 7
Dependent Claim
8 words
A formulation according to claim 5 employing 4-methyl-N-([(4-trifluoromethylphenyl)amino]carbonyl)benzenesulfonamide.
Claim 8
Dependent Claim
8 words
A formulation according to claim 5 employing 4-methoxy-N-([(4-trifluoromethylphenyl)amino]carbonyl)benzenesulfonamide.
Claim 9
Dependent Claim
8 words
A formulation accordaing to claim 5 employing 4-chloro-N-([(4-trifluoromethylphenyl)amino]carbonyl)benzenesulfonamide.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-07-03 | 1993-01-02 | 1993-07-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-07-03 | 1997-01-02 | 1997-07-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-07-03 | 2001-01-02 | 2001-07-04 | $7700.00 | Window Closed / Lapsed |