US4842866A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Slow release solid preparation
Assignee: Abbott Laboratories Ltd
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Filing: 1987-12-14
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Granted: 1989-06-27
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Expires: 2007-12-14
Abstract
Abstract A controlled, slow release, solid pharmaceutical preparation includes at least one active ingredient and a blend of sodium alginate and sodium-calcium alginate.
Inventors
- 👤 Rodney Horder
- 👤 Michael Banks
- 👤 Thomas H. Hoadley
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 18:43
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/205
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
22 words
A controlled, slow release, solid preparation comprising sodium alginate, sodium-calcium alginate and a therapeutically effective amount of at least one active ingredient.
Claim 2
Dependent Claim
22 words
A controlled, slow release, solid preparation comprising sodium alginate, sodium-calcium alginate and a therapeutically effective amount of at least one active ingredient.
Claim 3
Dependent Claim
12 words
The preparation of claim 1 further comprising lubricating, bulking, and binding agents.
Claim 4
Dependent Claim
8 words
The preparation of claim 1 in tablet form.
Claim 5
Dependent Claim
19 words
The preparation of claim 1 wherein the active ingredient is a pharmaceutical exceeding 50% by weight of the preparation.
Claim 6
Dependent Claim
31 words
The preparation of claim 1 wherein the pharmaceutical active ingredient is capable of releasing no more than 50% of the pharmaceutical active ingredient in the first five hours following oral administration.
Claim 7
Dependent Claim
31 words
A controlled, slow release, solid preparation comprising 600 mg of buflomedil hydrochloride, 25 to 150mg of sodium-calcium alginate, 160 to 400 mg sodium alginate and lubricating and binding agents as needed.
Claim 8
Dependent Claim
31 words
A controlled, slow release, solid preparation comprising 600 mg of buflomedil hydrochloride, 25 to 150mg of sodium-calcium alginate, 160 to 400 mg sodium alginate and lubricating and binding agents as needed.
Claim 9
Dependent Claim
26 words
The preparation of claim 6 comprising 80 mg of sodium-calcium alginate, 160 mg of sodium alginate, 4-5 mg of magnesium stearate and 30 mg of povidone.
Claim 10
Dependent Claim
34 words
A solid slow release preparation comprising 4 to 6 mg of tulobuterol hydrochloride, 75 to 400 mg of sodium-calcium alginate, 75 to 400 mg sodium alginate and lubricating, binding and bulking agents as needed.
Claim 11
Dependent Claim
34 words
A solid slow release preparation comprising 4 to 6 mg of tulobuterol hydrochloride, 75 to 400 mg of sodium-calcium alginate, 75 to 400 mg sodium alginate and lubricating, binding and bulking agents as needed.
Claim 12
Dependent Claim
23 words
The preparation of claim 8 wherein said lubricating agent is magnesium stearate, said binding agent is povidone and said bulking agent is lactose.
Claim 13
Dependent Claim
53 words
The process for the production of a controlled, slow release pharmaceutical preparation, said process comprising blending in the presence of water, sodium alginate, sodium-calcium alginate, a therapeutically effective amount of at least one pharmaceutically active ingredient and binders, lubricants and bulking agents as needed; and then forming the resultant preparation into a tablet.
Claim 14
Dependent Claim
53 words
The process for the production of a controlled, slow release pharmaceutical preparation, said process comprising blending in the presence of water, sodium alginate, sodium-calcium alginate, a therapeutically effective amount of at least one pharmaceutically active ingredient and binders, lubricants and bulking agents as needed; and then forming the resultant preparation into a tablet.
References Cited (Backward Citations)
FR985218A
Cited
US3640741A
Cited
GB1355985A
Cited
EP0188040A1
Cited
JPH05176415A
Cited
JPH05176413A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-06-26 | 1992-12-26 | 1993-06-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-06-26 | 1996-12-26 | 1997-06-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-06-26 | 2000-12-26 | 2001-06-27 | $7700.00 | Window Closed / Lapsed |