US4839174A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Novel transdermal nicotine patch
Assignee: McNeil AB
•
Filing: 1987-10-05
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Granted: 1989-06-13
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Expires: 2007-10-05
Abstract
Abstract A controlled release transdermal delivery system for nicotine administration. The system comprises an impermeable backing layer, a polyurethane matrix layer containing between about 5 wt % and 50 wt % nicotine, and an adhesive skin-contacting layer. The system is designed to administer nicotine for smoking cessation therapy or other uses over a period of 24 hours or more.
Inventors
- 👤 Richard W. Baker
- 👤 Frank Kochinke
- 👤 Carl Huang
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 16:23
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/70; A61K9/7023; A61K9/703; A61K9/7038; A61K9/7046; A61K9/7069; A61F; A61F5/00; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/465; A61K9/7084
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
57 words
A transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyurethane, said matrix layer having a first and second face; (b) an impermeable and opaque backing layer contacting said first face; and (c) an amine-resistant bioadhesive layer contacting said second face.
Claim 2
Dependent Claim
57 words
A transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyurethane, said matrix layer having a first and second face; (b) an impermeable and opaque backing layer contacting said first face; and (c) an amine-resistant bioadhesive layer contacting said second face.
Claim 3
Dependent Claim
58 words
A transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyester-type polyurethane, said matrix layer having a first and second face; (b) an impermeable and opaque backing layer contacting said first face; and (c) an amine-resistant bioadhesive layer contacting said second face.
Claim 4
Dependent Claim
58 words
A transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyester-type polyurethane, said matrix layer having a first and second face; (b) an impermeable and opaque backing layer contacting said first face; and (c) an amine-resistant bioadhesive layer contacting said second face.
Claim 5
Dependent Claim
27 words
The transdermal device of claim 1 or claim 2, wherein said matrix layer comprises between about 5% and 25% nicotine and between about 95% and 75% polyurethane.
Claim 6
Dependent Claim
19 words
The transdermal device of claim 1 or claim 2, wherein said amine-resistant bioadhesive layer comprises double-sided medical adhesive tape.
Claim 7
Dependent Claim
25 words
The transdermal device of claim 1 or claim 2, wherein said amine-resistant bioadhesive layer has a nicotine flux between 25 and 300 μg/cm 2 ·h.
Claim 8
Independent Claim
74 words
A method for prolonged transdermal delivery of nicotine to a patient, comprising applying to said patient a transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyether-type polyurethane, said matrix layer having a first and second face; (b) am impermeable and opaque backing layer contacting said first face; and (c) an amine-resistant bioadhesive layer contacting said second face.
Claim 9
Independent Claim
74 words
A method for prolonged transdermal delivery of nicotine to a patient, comprising applying to said patient a transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyether-type polyurethane, said matrix layer having a first and second face; (b) am impermeable and opaque backing layer contacting said first face; and (c) an amine-resistant bioadhesive layer contacting said second face.
Claim 10
Independent Claim
88 words
A method for prolonged transdermal delivery of nicotine to a patient, comprising applying to said patient a transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyether-type polyurethane, said matrix layer having a first and second face; (b) an impermeable and opaque backing layer contacting said first face, (c) an amine-resistant bioadhesive layer contacting said second face, said transdermal nicotine device remaining active on the skin for a period of one day.
Claim 11
Independent Claim
88 words
A method for prolonged transdermal delivery of nicotine to a patient, comprising applying to said patient a transdermal nicotine delivery device, comprising a laminate of: (a) a matrix layer comprising between about 5% and 50% nicotine and between about 95% and 50% polyether-type polyurethane, said matrix layer having a first and second face; (b) an impermeable and opaque backing layer contacting said first face, (c) an amine-resistant bioadhesive layer contacting said second face, said transdermal nicotine device remaining active on the skin for a period of one day.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-06-12 | 1992-12-12 | 1993-06-13 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-06-12 | 1996-12-12 | 1997-06-13 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-06-12 | 2000-12-12 | 2001-06-13 | $7700.00 | Window Closed / Lapsed |