US4836209A
Expired / Lapsed
US
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NMR imaging of moving material using variable spatially selected excitation
Assignee: Leland Stanford Junior University
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Filing: 1988-05-11
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Granted: 1989-06-06
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Expires: 2008-05-11
Abstract
Abstract A method of imaging material flowing through a slab in a body using magnetic resonance techniques includes placing the body in a magnetic field including a first magnetic (z) gradient for slab thickness selection. A first rf pulse (180°) is applied to the body at a frequency band and of sufficient strength to flip nuclear spins located essentially in the slab. After allowing moving material in the slab to flow from the slab, a second rf (90°) pulse is applied to the body at a frequency band of sufficient strength to flip the nuclear spins in the slab for generating a signal. First image date in an X-Z plane is obtained from the nuclear spins flipped by the second 90° rf pulse. Thereafter, a third 180° rf pulse is applied to the body. In one embodiment the third rf pulse is non-selective and is of sufficient strength to flip nuclear spins in the body including but not limited to the slab. Moving material is again allowed to flow from the slab, and a fourth 90° rf pulse is then applied to the body at a frequency band and of sufficient strength to flip nuclear spins in the slab. Second image data in an X-Z plane is obtained from nuclear spins flipped by the fourth 90° rf pulse. The first image data is subtracted from the second image data to obtain third image data of moving material through the slab. Alternatively, the first image data and the second image data can be gated to different portions of a cardiac cycle whereby the flow of moving material differs in obtaining the first image data from the flow of moving material in obtaining the second image data. Direction sensitivity can be obtained by selective spatial excitation of portions of the body.
Inventors
- 👤 Dwight G. Nishimura
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-25 05:45
CPC Classifications
G; G01; G01R; G01R33/00; G01R33/20; G01R33/44; G01R33/48; G01R33/54; G01R33/56; G01R33/563
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
264 words
A method of projection imaging moving material in a three-dimensional slab through a body using magnetic resonance techiniques comprising the steps of (a) placing said body in a magnetic field including a first magnetic gradient (z) for slab selection, (b) applying a first rf pulse to said body at a frequency band and of sufficient strength to flip by a first angle nuclear spins limited essentially to said slab, (c) allowing moving material outside of said slab to flow into said slab, (d) applying at least a second rf pulse to said body at a frequency band and of sufficient strength to flip nuclear spins in said slab by a second angle suitable for generating a signal, thereby flipping nuclear spins of moving material that moves into said slab during step c, (e) obtaining first projection image data in an X-Z plane from said nuclesr spins flipped by said second rf pulse, (f) applying a third rf pulse to said body at a frequency band and of sufficient strength to flip nuclear spins in said body, including said slab but not limited to said slab by said first angle, (g) repeating step c, (h) repeating step d with a fourth rf pulse identical to said second pulse, (i) obtaining second projection image data in said X-Z plane from said nuclear spins flipped by said fourth rf pulse, (j) subtracting said first projection image data from said second projection image data to obtain a third image data of moving material moved to said slab, and (k) imaging said X-Z plane with said third image data.
Claim 2
Independent Claim
264 words
A method of projection imaging moving material in a three-dimensional slab through a body using magnetic resonance techiniques comprising the steps of (a) placing said body in a magnetic field including a first magnetic gradient (z) for slab selection, (b) applying a first rf pulse to said body at a frequency band and of sufficient strength to flip by a first angle nuclear spins limited essentially to said slab, (c) allowing moving material outside of said slab to flow into said slab, (d) applying at least a second rf pulse to said body at a frequency band and of sufficient strength to flip nuclear spins in said slab by a second angle suitable for generating a signal, thereby flipping nuclear spins of moving material that moves into said slab during step c, (e) obtaining first projection image data in an X-Z plane from said nuclesr spins flipped by said second rf pulse, (f) applying a third rf pulse to said body at a frequency band and of sufficient strength to flip nuclear spins in said body, including said slab but not limited to said slab by said first angle, (g) repeating step c, (h) repeating step d with a fourth rf pulse identical to said second pulse, (i) obtaining second projection image data in said X-Z plane from said nuclear spins flipped by said fourth rf pulse, (j) subtracting said first projection image data from said second projection image data to obtain a third image data of moving material moved to said slab, and (k) imaging said X-Z plane with said third image data.
Claim 3
Dependent Claim
43 words
The method as defined by claim 1 wherein step b further includes flippin nuclear spins on one side of said slab, and step j obtains third image data of moving material flowing into said slab from a side opposite from said one side.
Claim 4
Dependent Claim
21 words
The method as defined by claim 1 wherein said first angle is approximately 180° and said second angle is approximately 90°.
Claim 5
Dependent Claim
25 words
The method as defined by claim 3 wherein said steps (d) and h) occur when the longitudinal magnetization of excited static material is approximately zero.
Claim 6
Dependent Claim
25 words
The method as defined by claim 1 wherein step (d) includes applying a 90° rf pulse and a 180° pulse for spin echo signal detection.
Claim 7
Dependent Claim
23 words
The method as defined by claim 1 wherein steps (a) through (k) are repeated for other slabs to increase the field of view.
Claim 8
Independent Claim
212 words
A method of imaging moving material in a slab through a body using magnetic resonance techniques comprising the steps of (a) placing said body in a magnetic field including a first magnetic gradient (z) for slab selection, (b) applying a first rf pulst to said body at a frequency band and of sufficient strength to flip by a first angle nuclear spins limited to the region on one side of said slab, (c) allowing moving material in said slab to flow from said slab and material from said one region to flow into said slab, (d) applying a second rf pulse to said body at a frequency band and of sufficient strength to flip nuclear spins in said slab by a second angle suitable for generating a signal, (e) obtaining first image data in an X-Z plane from said nuclear spins flipped by said second rf pulse, (f) repeating step c without exciting said region, (h) repeating step d, (i) obtaining second image data in an X-Z plane in said slab from said nuclear spins flipped by the step h rf pulse, (j) subtracting said first image data from said second image data to obtain a third image data of moving material to said slab, and (k) imaging said third image data.
Claim 9
Independent Claim
212 words
A method of imaging moving material in a slab through a body using magnetic resonance techniques comprising the steps of (a) placing said body in a magnetic field including a first magnetic gradient (z) for slab selection, (b) applying a first rf pulst to said body at a frequency band and of sufficient strength to flip by a first angle nuclear spins limited to the region on one side of said slab, (c) allowing moving material in said slab to flow from said slab and material from said one region to flow into said slab, (d) applying a second rf pulse to said body at a frequency band and of sufficient strength to flip nuclear spins in said slab by a second angle suitable for generating a signal, (e) obtaining first image data in an X-Z plane from said nuclear spins flipped by said second rf pulse, (f) repeating step c without exciting said region, (h) repeating step d, (i) obtaining second image data in an X-Z plane in said slab from said nuclear spins flipped by the step h rf pulse, (j) subtracting said first image data from said second image data to obtain a third image data of moving material to said slab, and (k) imaging said third image data.
Claim 10
Dependent Claim
26 words
The method as defined by claim 7 wherein said step d) includes applying a 90° rf pulse and a 180° pulse for spin echo signal detection.
Claim 11
Dependent Claim
21 words
The method as defined by claim 7 wherein said first angle is approximately 180° and said second angle is approximately 90°.
Claim 12
Dependent Claim
23 words
The method as defined by claim 7 wherein steps (a) through (k) are repeated for other slabs to increase the field of view.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-06-05 | 1992-12-05 | 1993-06-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-06-05 | 1996-12-05 | 1997-06-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-06-05 | 2000-12-05 | 2001-06-06 | $7700.00 | Window Closed / Lapsed |