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US4810246A Expired / Lapsed US ⏱️ 0.0 years remaining

Disposable cell culture chamber with remote access

Assignee: L Vad Technology Inc
•
Filing: 1987-11-04
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Granted: 1989-03-07
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Expires: 2007-11-04
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Abstract

Abstract A combination is provided of a percutaneous lead designed for implantation in the human body, which lead has a surface which is adapted to pass through and be exposed to the dermis of a patient when the device is implanted. Said surface is adapted to receive the growth of a cultured autogenous fibroblast coating on an etched, nanoporous surface. A liquid tight sealed removable, disposable chamber encloses said surface, said chamber being provided with openings for introduction therein of finely divided living dermal tissue suspended in a liquid carrier, thus providing a means for formation of the cultured surfaces which can be easily handled. The disposable chamber is removed and discarded at the time of surgery.

Inventors

  • 👤 Eldon E. Frisch
  • 👤 Adrian Kantrowitz
  • 👤 Paul S. Freed

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 00:52
CPC Classifications
A; A61; A61M; A61M39/00; A61M39/02; A61M39/0247; A61M2039/0261; A61M2039/0291

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 118 words
In combination: A. a percutaneous access device designed for implantation in the human body, said device having a component adapted to extend through the skin to provide access from outside of the body to a subcutaneous location within the body and having a peridermal component with a surface which is adapted to be implanted immediately beneath the dermis of a patient, said surface having a porous texture and thus being adapted to receive the growth thereon of a cultured autogenous fibroblast coating thereon, and B. a liquid tight sealed removable, disposable chamber enclosing said surface, said chamber being provided with a remotely accessible opening for introduction therein of finely divided living dermal tissue suspended in a liquid carrier.
Claim 2
Dependent Claim 118 words
In combination: A. a percutaneous access device designed for implantation in the human body, said device having a component adapted to extend through the skin to provide access from outside of the body to a subcutaneous location within the body and having a peridermal component with a surface which is adapted to be implanted immediately beneath the dermis of a patient, said surface having a porous texture and thus being adapted to receive the growth thereon of a cultured autogenous fibroblast coating thereon, and B. a liquid tight sealed removable, disposable chamber enclosing said surface, said chamber being provided with a remotely accessible opening for introduction therein of finely divided living dermal tissue suspended in a liquid carrier.
Claim 3
Dependent Claim 15 words
A device according to claim 1 wherein said chamber is formed of a silicone elastomer.
Claim 4
Dependent Claim 32 words
A device according to claim 1 wherein a tube is provided through said opening for addition of said dermal tissue and a second tube is provided to permit venting of said chamber.
Claim 5
Dependent Claim 11 words
A device according to claim 1 wherein said surface is nanoporous.
Claim 6
Dependent Claim 51 words
A device according to claim 1 wherein said component is a conduit attached to the top thereof adapted to extend exteriorly of the body of the patient and a conduit tube in fluid communication therewith extending from the bottom thereof which is adapted to be surgically implanted within the patients body.
Claim 7
Dependent Claim 47 words
A device according to claim 5 wherein a sterile plastic container surrounds said chamber and said catheters, said container being hermetically enclosed with the exception of an opening through which a tube connected to the opening in the chamber extends for addition of a dermal tissue suspension.

References Cited (Backward Citations)

US4605007A Cited
US4634422A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-03-06 1992-09-05 1993-03-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-03-06 1996-09-05 1997-03-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-03-06 2000-09-05 2001-03-07 $7700.00 Window Closed / Lapsed

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