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US4807620A Expired / Lapsed US ⏱️ 0.0 years remaining

Apparatus for thermal angioplasty

Assignee: Spectranetics LLC
•
Filing: 1987-05-22
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Granted: 1989-02-28
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Expires: 2007-05-22
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Abstract

Abstract An interventional therapeutic apparatus is described which includes a probe in the form of a transmission line such as coaxial cable. The probe is adapted to pass through the interior of a body cavity such as a blood vessel and includes an inductive load such as a ferrite bead at the remote end of the cable. Radio frequency energy is applied to the cable and converted into heat by a ferrite bead. As a result of the heat conversion by the ferrite bead, the remote end of the coaxial cable is heated to a sufficient temperature to provide the effect desired, for example to melt or otherwise remove plaque deposits in blood vessels.

Inventors

  • 👤 Bruno Strul
  • 👤 Tsvi Goldenberg

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 01:23
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/08; A61B17/00; A61B17/22; A61B2017/22001

Claims Analysis

Total Claims: 28
Claim 1
Independent Claim 144 words
In an interventional therapeutic apparatus for remote delivery of heat to body tissue, the combination which comprises: (a) a oscillator for providing an r.f. output signal within the range of 10 MHz to 2 GHz; (b) a transmission line having a proximal end connected to the oscillator for receiving the output signal and a distal end, the transmission line being constructed and arranged to pass through the interior of a body cavity; and (c) an inductive load dispose at the distal end of the transmission line, the inductive load comprising a magnetic material and operating to convert the r.f. signal transmitted through the transmission line into heat, the conversion being optimized at a predetermined frequency, the frequency of the output signal from the oscillator being set at substantially said predetermined frequency, whereby the inductive load is heated to a temperature sufficient for therapeutic effects.
Claim 2
Dependent Claim 144 words
In an interventional therapeutic apparatus for remote delivery of heat to body tissue, the combination which comprises: (a) a oscillator for providing an r.f. output signal within the range of 10 MHz to 2 GHz; (b) a transmission line having a proximal end connected to the oscillator for receiving the output signal and a distal end, the transmission line being constructed and arranged to pass through the interior of a body cavity; and (c) an inductive load dispose at the distal end of the transmission line, the inductive load comprising a magnetic material and operating to convert the r.f. signal transmitted through the transmission line into heat, the conversion being optimized at a predetermined frequency, the frequency of the output signal from the oscillator being set at substantially said predetermined frequency, whereby the inductive load is heated to a temperature sufficient for therapeutic effects.
Claim 3
Dependent Claim 37 words
The apparatus of claim 1 adapted for thermal angioplasty wherein the transmission line is constructed and arranged to pass through a blood vessel so that the occlusive effect of plaque residing within the vessel may be reduced.
Claim 4
Dependent Claim 29 words
The invention of claim 1 further including means for measuring the power reflected from the distal end of transmission line back to the proximal end of the transmission line.
Claim 5
Dependent Claim 35 words
The invention of claim 3 further including means for measuring the incident power applied to the proximal end of the transmission line by the oscillator, and means for adjusting the magnitude of the incident power.
Claim 6
Dependent Claim 68 words
The invention of claim 4 wherein the inductive load is characterized by a temperature rise up to a maximum value which is proportional to the magnitude of the difference between the incident and reflected power, whereby the temperature of the load and distal end of the transmission line can be controlled by adjusting the magnitude of the incident power while maintaining the reflected power at a predetermined level.
Claim 7
Dependent Claim 28 words
The invention of claim 5 wherein the inductive load is further characterized by a loss of ability to convert r.f. energy into heat at a preset maximum temperature.
Claim 8
Dependent Claim 11 words
The invention of claim 3 wherein the inductive load is ferrite.
Claim 9
Dependent Claim 43 words
The invention of claim 7 wherein the reflected power measuring means includes reflected power signal generating means for producing a reflected power signal representative of the magnitude of the power reflected from the distal end to the proximal end of the transmission line.
Claim 10
Dependent Claim 40 words
The invention of claim 8 wherein the oscillator further includes means for adjusting the frequency of said output signal and further including means responsive to the reflected power signal for controlling the frequency adjusting means to minimize the reflected power.
Claim 11
Dependent Claim 23 words
The invention of claim 9 further including incident power adjustment means for controlling the magnitude of the power delivered to the transmission line.
Claim 12
Dependent Claim 51 words
The invention of claim 10 further including means for providing an incident power signal representative of the magnitude of the power delivered to the transmission line by the oscillator and wherein the power adjustment means is responsive to the incident power signal for maintaining the delivered power at a present level.
Claim 13
Dependent Claim 19 words
The apparatus of claim 1 wherein the oscillator further includes means for adjusting the frequency of said output signal.
Claim 14
Dependent Claim 66 words
The invention of claim 12 further including means for measuring the power reflected from the distal end of the transmission line back to the proximal end of the transmission line, the reflected power measuring means being arranged to produce a reflected power signal and wherein the frequency adjusting means is responsive to the reflected power signal and arranged to minimize the magnitude of the reflected power.
Claim 15
Dependent Claim 158 words
A delivery system for thermal angioplasty comprising: (a) a coaxial transmission line having distal and proximal ends with a center conductor and an outer conducting shield and being arranged to pass through the interior of a blood vessel, the proximal end of the transmission line being adapted to be coupled to a source of r.f. energy; (b) a core of magnetic material disposed between the center conductor and outer shield at the distal end of the transmission line, the magnetic material being arranged to convert r.f. energy into heat; (c) a heat conductive cap closing the distal end of the transmission line and in heat conducting relationship to said core, whereby the application of r.f. energy to the proximal end of the transmission line will cause the core and cap to heat sufficiently to allow the distal end of the transmission line to be forced through plaque restricting deposits in the vessels and reduce the occlusive effect thereof.
Claim 16
Dependent Claim 158 words
A delivery system for thermal angioplasty comprising: (a) a coaxial transmission line having distal and proximal ends with a center conductor and an outer conducting shield and being arranged to pass through the interior of a blood vessel, the proximal end of the transmission line being adapted to be coupled to a source of r.f. energy; (b) a core of magnetic material disposed between the center conductor and outer shield at the distal end of the transmission line, the magnetic material being arranged to convert r.f. energy into heat; (c) a heat conductive cap closing the distal end of the transmission line and in heat conducting relationship to said core, whereby the application of r.f. energy to the proximal end of the transmission line will cause the core and cap to heat sufficiently to allow the distal end of the transmission line to be forced through plaque restricting deposits in the vessels and reduce the occlusive effect thereof.
Claim 17
Dependent Claim 58 words
The invention of claim 13 wherein the magnetic core is characterized by a temperature rise up to a predetermined maximum level which is proportional to the magnitude of the r.f. power applied to the proximal end of the transmission line with substantially minimum power being reflected back to the proximal end from the distal end of the line.
Claim 18
Dependent Claim 12 words
The delivery system of claim 15 wherein said magnetic material is ferrite.
Claim 19
Dependent Claim 21 words
The delivery system of claim 16 wherein the diameter of the distal end of the transmission line is approximately 2 mm.
Claim 20
Independent Claim 201 words
A device for reducing the occlusive effect of plaque in blood vessels in living tissue which comprises: (a) a coaxial transmission line having proximal and distal ends and a center conductor and outer conducting shield, the line being adapted to pass through the interior of a blood vessel; (b) a ferrite core disposed between the center conductor and outer shield at the distal end of the transmission line; (c) an electrically and heat conducting cap closing the distal end of the transmission line in electrical contact with the center conductor and outer shield and in heat conducting relationship with the ferrite core for providing a closed electrical circuit at the distal end of the transmission line and for receiving and dissipating heat generated in the ferrite core; and (d) power supply means coupled to the proximal end of the transmission line for applying r.f. energy thereto, whereby the r.f. energy is converted into heat by the ferrite core which heat is transmitted to the cap thereby enabling the distal end of the transmission line to ablate plaque deposits in contact with the cap and reduce the occlusive effect of such plaque within the vessel in which the transmission line is inserted.
Claim 21
Independent Claim 201 words
A device for reducing the occlusive effect of plaque in blood vessels in living tissue which comprises: (a) a coaxial transmission line having proximal and distal ends and a center conductor and outer conducting shield, the line being adapted to pass through the interior of a blood vessel; (b) a ferrite core disposed between the center conductor and outer shield at the distal end of the transmission line; (c) an electrically and heat conducting cap closing the distal end of the transmission line in electrical contact with the center conductor and outer shield and in heat conducting relationship with the ferrite core for providing a closed electrical circuit at the distal end of the transmission line and for receiving and dissipating heat generated in the ferrite core; and (d) power supply means coupled to the proximal end of the transmission line for applying r.f. energy thereto, whereby the r.f. energy is converted into heat by the ferrite core which heat is transmitted to the cap thereby enabling the distal end of the transmission line to ablate plaque deposits in contact with the cap and reduce the occlusive effect of such plaque within the vessel in which the transmission line is inserted.
Claim 22
Dependent Claim 42 words
The device as defined in claim 18 including means to adjust the frequency of the r.f. energy output from the power supply means to minimize the magnitude of energy reflected back to the proximal end from the distal end of the line.
Claim 23
Dependent Claim 21 words
The device as defined in claim 19 further including reflected power measuring means for measuring the magnitude of the reflected power.
Claim 24
Dependent Claim 43 words
The device as defined in claim 20 wherein the reflected power measuring means is further arranged to produce a reflected power signal representative of the magnitude of the reflected power and wherein the frequency adjusting means is responsive to the reflected power signal.
Claim 25
Dependent Claim 38 words
The device as defined in claim 21 further including means to adjust the magnitude of incident r.f. power applied to the proximal end of the transmission line and means to measure the magnitude of the incident r.f. power.
Claim 26
Dependent Claim 58 words
The device as defined in claim 22 wherein the incident power measuring means is further arranged to produce an incident power signal representative of the magnitude of the incident power and wherein the power adjustment means is responsive to the incident power signal and arranged to maintain the magnitude of the incident r.f. power at a preset level.
Claim 27
Dependent Claim 33 words
The device as defined in claim 18 wherein the power supply means is further arranged to apply r.f. energy to the transmission line within the frequency range of 1 MHz to 3 GHz.
Claim 28
Dependent Claim 28 words
The device as defined in claim 24 wherein the frequency of r.f. energy applied to the transmission line is within the range of 500 MHz to 1.2 GHz.

References Cited (Backward Citations)

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US3934115A Cited
US4154246A Cited
US4256945A Cited
US4701587A Cited
US4582057A Cited
US4446874A Cited
US4534347A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-02-28 1992-08-29 1993-02-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-02-28 1996-08-29 1997-02-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-02-28 2000-08-29 2001-02-28 $7700.00 Window Closed / Lapsed

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