US4806621A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
Assignee: Massachusetts Institute of Technology
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Filing: 1986-01-21
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Granted: 1989-02-21
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Expires: 2006-01-21
Abstract
Abstract A novel series of articles useful as medical devices, implants and protheses are provided which utilize poly(iminocarbonate) polymeric matrices. These articles are biocompatible, have excellent mechanical properties and degrade into non-toxic residues after introduction in vivo. The articles may be formed in any desired dimensions and configuration and may take specific shape as biodegradable sutures or as orthopedic appliances such as bone plates and the like.
Inventors
- 👤 Joachim Kohn
- 👤 Robert S. Langer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:41
CPC Classifications
C; C08; C08G; C08G64/00; C08G64/04; C08G64/06; C08G64/08; C08G64/12; A; A61; A61L; A61L17/00; A61L17/06; A61L17/10; A61L27/00; A61L27/14; A61L27/18; A61L31/00; A61L31/04; A61L31/06
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
59 words
An article useful for implantation in an animal comprising a mixture of (a) a solid biocompatible, bioerodible, hydrophobic polyiminocarbonate composition having the recurring structrual unit: ##STR8## wherein R is a divalent aromatic group comprising a non-fused ring and n is at least 2, said article degrading into non-toxic residues after introduction in vivo and (b) a pharmacologically active composition.
Claim 2
Dependent Claim
59 words
An article useful for implantation in an animal comprising a mixture of (a) a solid biocompatible, bioerodible, hydrophobic polyiminocarbonate composition having the recurring structrual unit: ##STR8## wherein R is a divalent aromatic group comprising a non-fused ring and n is at least 2, said article degrading into non-toxic residues after introduction in vivo and (b) a pharmacologically active composition.
Claim 3
Dependent Claim
10 words
The article recited in claim 1 wherein R is phenylene.
Claim 4
Dependent Claim
10 words
The article recited in claim 1 wherein R is: ##STR9##
Claim 5
Dependent Claim
11 words
The article as recited in claim 1 wherein R is: ##STR10##
Claim 6
Dependent Claim
18 words
The article as recited in claim 1 wherein R is: ##STR11## and R' is C,-C 6 lower alkylene.
Claim 7
Dependent Claim
21 words
The article of claim 1 wherein R is: ##STR12## X is a heteroatom and n is an integer greater than 1.
Claim 8
Dependent Claim
9 words
The article of claim 1 wherein R is: ##STR13##
Claim 9
Dependent Claim
32 words
The process for administering a pharmacologically active composition to an animal which comprises implanting in said animal the article of any one of claims 2, 3, 4, 5, 6, 7 or 1.
References Cited (Backward Citations)
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US3887699A
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US4419340A
Cited
US4554155A
Cited
US4131648A
Cited
US4122158A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-02-21 | 1992-08-22 | 1993-02-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-02-21 | 1996-08-22 | 1997-02-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-02-21 | 2000-08-22 | 2001-02-21 | $7700.00 | Window Closed / Lapsed |