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US4806316A Expired / Lapsed US ⏱️ 0.0 years remaining

Disposable device for use in chemical, immunochemical and microorganism analysis

Assignee: Becton Dickinson and Co
•
Filing: 1987-03-17
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Granted: 1989-02-21
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Expires: 2007-03-17
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Abstract

Abstract A substantially rigid, multi-well, self-pipetting device for use in chemical, immunochemical and microorganism analysis is provided. It includes a frame and a plurality of test wells disposed within the frame. A filing manifold communicates with each of the test wells through a filling passageway. A docking port on the periphery of the device receives a reservoir holding a fluid specimen. The docking port communicates with the filling manifold through a filling port and a filling channel. A vent control system also communicates with the test wells and is comprised of one or more vent manifolds, and/or valves to a vent manifold, and/or one or more vent holes to the ambient atmosphere. Any vent holes present are temporarily closed. With the device in its operational position, the test wells, filling channel, filling manifold and filling port are located at a level lower than the surface of the fluid in the reservoir, and the vent manifold and/or vent holes are positioned higher than the surface of the fluid in the reservoir. The test wells are connected to the filling manifold and the vent control system according to the filling sequence. The reservoir is also connected to the vent control system through a vent port and a vent channel. In use, the fluid specimen in the reservoir flows to the filling manifold and fills the test wells vented to the reservoir or to the ambient atmosphere.

Inventors

  • 👤 Raymond Johnson
  • 👤 Dwight Livingston
  • 👤 Robert C. Tite
  • 👤 Sheila J. Wood-Helie

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-26 14:52
CPC Classifications
B; B01; B01L; B01L3/00; B01L3/50; B01L3/502; C; C12; C12M; C12M23/00; C12M23/02; C12M23/12; C12M33/00; C12M33/04; G; G01; G01N; G01N35/00; G01N35/00029; G01N2035/00099; G01N2035/00148; Y; Y10; Y10S; Y10S435/00; Y10S435/81

Claims Analysis

Total Claims: 25
Claim 1
Independent Claim 137 words
A multi-well, self-pipetting device for use in chemical, immunochemical and microorganism analysis, said device comprising: (1) a frame having in operational orientation a body and a periphery; (2) a plurality of test wells disposed within said body; (3) a filling manifold located within said frame, said filling manifold being in fluid communication with each of said plurality of test wells; (4) a venting manifold located within said frame in a position above the filling manifold and above the plurality of test wells, said venting manifold being in fluid communication with each of said plurality of test wells; and (5) a docking port for receiving a container holding a fluid specimen, said docking port being located on the periphery of said frame, said docking port being in fluid communication with said filling manifold and with said venting manifold.
Claim 2
Dependent Claim 137 words
A multi-well, self-pipetting device for use in chemical, immunochemical and microorganism analysis, said device comprising: (1) a frame having in operational orientation a body and a periphery; (2) a plurality of test wells disposed within said body; (3) a filling manifold located within said frame, said filling manifold being in fluid communication with each of said plurality of test wells; (4) a venting manifold located within said frame in a position above the filling manifold and above the plurality of test wells, said venting manifold being in fluid communication with each of said plurality of test wells; and (5) a docking port for receiving a container holding a fluid specimen, said docking port being located on the periphery of said frame, said docking port being in fluid communication with said filling manifold and with said venting manifold.
Claim 3
Dependent Claim 25 words
A device in accordance with claim 1 wherein said docking port is located in an intermediate position between said filling manifold and said venting manifold.
Claim 4
Dependent Claim 21 words
A device in accordance with claim 1 wherein a reservoir for containing a fluid specimen is affixed to said docking port.
Claim 5
Dependent Claim 17 words
A kit including the device of claim 1 having reagents disposed in said plurality of test wells.
Claim 6
Dependent Claim 23 words
A device in accordance with claim 1 comprising at least a base layer, a passageway circuit layer and a cover layer laminated together.
Claim 7
Dependent Claim 20 words
A device in accordance with claim 1 wherein a reservoir for containing a fluid reagent is disposed within said frame.
Claim 8
Dependent Claim 14 words
A device in accordance with claim 1 which is formed in a curvilinear shape.
Claim 9
Dependent Claim 23 words
A device in accordance with claim 1 wherein predetermined groups of the plurality of test wells are coupled in sequence by interconnecting passageways.
Claim 10
Dependent Claim 67 words
A device in accordance with claim 8 wherein an auxiliary venting passageway is in fluid communication with at least one of said plurality of test wells of one of said groups, said auxiliary passageway being isolated from said venting manifold and said auxiliary passageway leading to a venting port and means for exposing said venting port to ambient pressure or to fluid communication with said venting manifold.
Claim 11
Dependent Claim 16 words
A device in accordance with claim 1 comprising a base and a second piece laminated together.
Claim 12
Dependent Claim 92 words
A device in accordance with claim 10 further comprising a third piece laminated together with the base and the second piece, and the base is substantially planar having a first surface and a second surface, and has said plurality of test wells bored therethrough; said manifolds and passageways are formed on the first surface of the base; the second piece is a mating cover which is secured to the first surface of said base; and the third piece is a mating cover which is secured to the second surface of said base.
Claim 13
Dependent Claim 46 words
A device in accordance with claim 10 wherein the base is substantially planar; said plurality of test wells, manifolds and passageways are formed on a surface of the base; and the second piece is a mating cover which is secured to the surface of said base.
Claim 14
Dependent Claim 21 words
A device in accordance with claim 12 having an axis in the substantially planar base about which the device is folded.
Claim 15
Dependent Claim 125 words
A multi-well, self pipetting device for use in chemical, immunochemical and microoroganism analysis, said device comprising: (1) a frame having in operational orientation a body and a periphery; (2) a plurality of test wells disposed within said body; (3) a filling manifold located within said frame, said filling manifold being in fluid communication with each of said plurality of test wells; (4) a venting manifold located within said frame in a position above the filling manifold and above the plurality of test wells, said venting manifold being in fluid communication with each of said plurality of test wells; and (5) a reservoir for containing a fluid reagent disposed within said frame, said reservoir being in fluid communication with said filling manifold and said venting manifold.
Claim 16
Dependent Claim 125 words
A multi-well, self pipetting device for use in chemical, immunochemical and microoroganism analysis, said device comprising: (1) a frame having in operational orientation a body and a periphery; (2) a plurality of test wells disposed within said body; (3) a filling manifold located within said frame, said filling manifold being in fluid communication with each of said plurality of test wells; (4) a venting manifold located within said frame in a position above the filling manifold and above the plurality of test wells, said venting manifold being in fluid communication with each of said plurality of test wells; and (5) a reservoir for containing a fluid reagent disposed within said frame, said reservoir being in fluid communication with said filling manifold and said venting manifold.
Claim 17
Dependent Claim 17 words
A kit including the device of claim 14 having reagents disposed in said plurality of test wells.
Claim 18
Dependent Claim 23 words
A device in accordance with claim 14 comprising at least a base layer, a passageway circuit layer and a cover layer laminated together.
Claim 19
Dependent Claim 14 words
A device in accordance with claim 14 which is formed in a curvilinear shape.
Claim 20
Dependent Claim 23 words
A device in accordance with claim 14 wherein predetermined groups of the plurality of test wells are coupled in sequence by interconnecting passageways.
Claim 21
Dependent Claim 67 words
A device in accordance with claim 18 wherein an auxiliary venting passageway is in fluid communication with at least one of said plurality of test wells of one of said groups, said auxiliary passageway being isolated from said venting manifold and said auxiliary passageway leading to a venting port and means for exposing said venting port to ambient pressure or to fluid communication with said venting manifold.
Claim 22
Dependent Claim 16 words
A device in accordance with claim 14 comprising a base and a second piece laminated together.
Claim 23
Dependent Claim 92 words
A device in accordance with claim 20 further comprising a third piece laminated together with the base and the second piece, and the base is substantially planar having a first surface and a second surface, and having said plurality of test wells bored therethrough; said manifolds and passageways are formed on the first surface of the base; the second piece is a mating cover which is secured to the first surface of said base; and the third piece is a mating cover which is secured to the second surface of said base.
Claim 24
Dependent Claim 44 words
A device in accordance with claim 20 wherein the base is substantially planar having said plurality of test wells, manifolds and passageways formed on a surface thereof and the second piece is a mating cover which is secured to the surface of said base.
Claim 25
Dependent Claim 21 words
A device in accordance with claim 22 having an axis in the substantially planar base about which the device is folded.

References Cited (Backward Citations)

US3957583A Cited
US4018652A Cited
US4207394A Cited
US4116775A Cited
US4318994A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1992-02-21 1992-08-22 1993-02-21 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1996-02-21 1996-08-22 1997-02-21 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2000-02-21 2000-08-22 2001-02-21 $7700.00 Window Closed / Lapsed

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