US4803977A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method and apparatus for the diagnosis of respiratory diseases and allergies
Assignee: Mallinckrodt Inc
•
Filing: 1987-03-27
•
Granted: 1989-02-14
•
Expires: 2007-03-27
Abstract
Abstract Method and apparatus for coating the airways of the lung of a patient substantially uniformly with a mist formed by aspirating a liquid which includes restricting the maximum size of the particles of the mist to about 1.2 microns with the major portion of the particles being in the range of 0.056 microns to 1 micron causing the mist to behave as a gas, conduits for feeding the mist together with a gas containing oxygen to a patient to be inhaled during the normal breathing process, and valves connected with the conduits for diverting the exhaled mist and gas through a discharge path. By radioactively tagging the liquid prior to production of the mist, the uniform deposition of the mist throughout the entire lung without encountering heavy accumulations in the large airways and at branch points, enables the production of high definition image scans of the lung.
Inventors
- 👤 Carl P. Kremer, Jr.
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-24 10:08
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/41; A61B5/411; A61B5/08; A61B5/0813
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
280 words
A method of diagnosing diseases, comprising: (a) continuously producing a radioactive mist having particles that do not exceed about 1.2 microns in diameter with a major portion of the particles being within the range of about 0.056 microns to about 1 micron, by continuously aspirating a radioactive liquid utilizing gas under pressure; (b) continuously introducing the radioactive mist into a first conduit through a first inlet therein; (c) continuously admitting a gas containing oxygen into the first conduit through a second inlet therein; (d) continuously mixing the gas containing oxygen with said radioactive mist in said first conduit to form a radioactive aerosol mixture; (e) passing the radioactive aerosol mixture from the first conduit to a second conduit through a first unidirectional control valve that permits unidirectional flow from the first conduit to the second conduit; (f) feeding the radioactive aerosol mixture from the second conduit into a patient's airways during the patient's breathing to substantially uniformly distribute the radioactive aerosol mixture throughout the patient's airways and deposit the radioactive mist on surfaces therein; (g) receiving exhaled aerosol from the patient's airway into the second conduit during the patient's breathing; (h) passing exhaled aerosol from the second conduit through a second unidirectional flow valve to permit unidirectional flow of exhaled aerosol from inside the second conduit to outside the second conduit with the first unidirectional flow valve preventing exhaled aerosol in the second conduit from passing into the first conduit; (i) preventing development of excessive pressure within the first conduit while exhaled aerosol is being received into the second conduit during the patient's breathing; and (j) producing radioactive image scans of the patient's airways after depositing the radioactive mist therein.
Claim 2
Independent Claim
280 words
A method of diagnosing diseases, comprising: (a) continuously producing a radioactive mist having particles that do not exceed about 1.2 microns in diameter with a major portion of the particles being within the range of about 0.056 microns to about 1 micron, by continuously aspirating a radioactive liquid utilizing gas under pressure; (b) continuously introducing the radioactive mist into a first conduit through a first inlet therein; (c) continuously admitting a gas containing oxygen into the first conduit through a second inlet therein; (d) continuously mixing the gas containing oxygen with said radioactive mist in said first conduit to form a radioactive aerosol mixture; (e) passing the radioactive aerosol mixture from the first conduit to a second conduit through a first unidirectional control valve that permits unidirectional flow from the first conduit to the second conduit; (f) feeding the radioactive aerosol mixture from the second conduit into a patient's airways during the patient's breathing to substantially uniformly distribute the radioactive aerosol mixture throughout the patient's airways and deposit the radioactive mist on surfaces therein; (g) receiving exhaled aerosol from the patient's airway into the second conduit during the patient's breathing; (h) passing exhaled aerosol from the second conduit through a second unidirectional flow valve to permit unidirectional flow of exhaled aerosol from inside the second conduit to outside the second conduit with the first unidirectional flow valve preventing exhaled aerosol in the second conduit from passing into the first conduit; (i) preventing development of excessive pressure within the first conduit while exhaled aerosol is being received into the second conduit during the patient's breathing; and (j) producing radioactive image scans of the patient's airways after depositing the radioactive mist therein.
Claim 3
Dependent Claim
34 words
The method of claim 1 further including the step of filtering out large particles from the radioactive aerosol mixture prior to passing the radioactive aerosol mixture from the first conduit to the second conduit.
Claim 4
Dependent Claim
71 words
The method of claim 2 wherein the large particles are filtered out of the radioactive aerosol mixture by passing the radioactive aerosol mixture in a circuitous path past a plurality of inclined baffles in a large particle trap so as to remove particles colliding with the baffles by converting the particles that collide with the baffles to a liquid and draining the thus formed liquid into said radioactive liquid being aspirated.
Claim 5
Dependent Claim
47 words
The method of claim 1 further including the step of filtering exhaled gas passing from inside the second conduit to outside the second conduit through the second unidirectional flow valve so as to remove radioactive mist from the exhaled gas passing through the second unidirectional flow valve.
Claim 6
Dependent Claim
35 words
The method of claim 1 wherein the step of preventing development of excessive pressure within the first conduit includes the step providing an undulating bellows that forms at least a portion of the first conduit.
Claim 7
Dependent Claim
49 words
The method of claim 1 wherein the step of preventing development of excessive pressure within the first conduit includes the step of venting excess pressure from the first conduit through a unidirectional relief valve permitting unidirectional flow of gas from inside the first conduit to outside the first conduit.
Claim 8
Dependent Claim
24 words
The method of claim 6 further including the step of filtering radioactive mist from gas passing through said relief valve from said first conduit.
Claim 9
Dependent Claim
18 words
The method of claim 1 wherein approximately 90% of the mist particles are under 1 micron in size.
Claim 10
Dependent Claim
21 words
The method of claim 1 wherein said gas under pressure is applied at a rate of about 6-10 liters per minute.
References Cited (Backward Citations)
US2840074A
Cited
US3863630A
Cited
US3976050A
Cited
US4116387A
Cited
US4094317A
Cited
US4174712A
Cited
US4113809A
Cited
US4177945A
Cited
US4251033A
Cited
US4256100A
Cited
US4660547A
Cited
US4510929A
Cited
US4598704A
Cited
US4598704B1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-02-14 | 1992-08-15 | 1993-02-14 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-02-14 | 1996-08-15 | 1997-02-14 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-02-14 | 2000-08-15 | 2001-02-14 | $7700.00 | Window Closed / Lapsed |