US4797368A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Adeno-associated virus as eukaryotic expression vector
Assignee: HEALTH AND HUMAN SERVICES United States, AS REPRESENTED BY DEPARTMENT OF
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Filing: 1985-03-15
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Granted: 1989-01-10
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Expires: 2005-03-15
Abstract
Abstract The present invention relates to a vector comprising part of AAV DNA contained in a plasmid and capable of being packaged into AAV particles and functioning as a vector for stable integration and expression of a gene in eukaryotic cells when under control of an AAV transcription promoter. A method of preparing such plasmids which are packagable and rescuable is also described.
Inventors
- 👤 Barrie J. Carter
- 👤 Jon D. Tratschin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 12:31
CPC Classifications
C; C12; C12N; C12N15/00; C12N15/09; C12N15/63; C12N15/79; C12N15/85; C12N15/86; C07; C07K; C07K14/00; C07K14/005; C12N2750/00; C12N2750/00011; C12N2750/14011; C12N2750/14111; C12N2750/14122; C12N2750/14141; C12N2750/14143
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
47 words
A vector comprising part of AAV DNA contained in a plasmid and capable of being packaged into AAV particles and functioning as a vector for stable maintenance or expression of a gene or a DNA sequence in eukaryotic cells when under control of an AAV transcription promotor.
Claim 2
Dependent Claim
47 words
A vector comprising part of AAV DNA contained in a plasmid and capable of being packaged into AAV particles and functioning as a vector for stable maintenance or expression of a gene or a DNA sequence in eukaryotic cells when under control of an AAV transcription promotor.
Claim 3
Dependent Claim
13 words
The vector of claim 1 wherein said AAV DNA containing plasmid is pAVdlK12.
Claim 4
Dependent Claim
26 words
The vector of claim 1 being rescuable from eukaryotic cells either by infection with helper adenovirus or by infection with helper adenovirus and wily type AAV.
Claim 5
Dependent Claim
14 words
The plasmid of claim 2 having an American Type Culture Collection accession number 39999.
References Cited (Backward Citations)
US4419446A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-01-10 | 1992-07-11 | 1993-01-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-01-10 | 1996-07-11 | 1997-01-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-01-10 | 2000-07-11 | 2001-01-10 | $7700.00 | Window Closed / Lapsed |