US4797260A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antibody testing system
Assignee: HUNTINGTON-CHASE Ltd
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Filing: 1987-01-27
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Granted: 1989-01-10
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Expires: 2007-01-27
Abstract
Abstract A compound is bound to a membrane which is reactive to a component in a fluid sample which is being tested. Under the membrane a porous support is added. The fluid sample suspected of containing a specific component is drawn over the membrane and into the porous support by a piston and cylinder arrangement.
Inventors
- 👤 James E. Parker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 09:00
CPC Classifications
B; B01; B01D; B01D61/00; B01D61/14; B01D61/18; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54366; Y; Y10; Y10S; Y10S436/00; Y10S436/807
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
111 words
An apparatus for testing, comprising: a membrane having a component reactive with a specific compound bound to the membrane, said membrane allowing the passage of liquid; a body member having: an internal piston housing; and a porous membrane support mounted adjacent said piston housing having a first side adjacent to and contacting said membrane and a second side defining the upper surface of said piston housing; and a piston, sealingly engaged with said piston housing for movement from a first position to a second position within said piston housing to create a zone of reduced pressure below said porous membrane support to facilitate passage of liquid through said porous membrane support.
Claim 2
Independent Claim
111 words
An apparatus for testing, comprising: a membrane having a component reactive with a specific compound bound to the membrane, said membrane allowing the passage of liquid; a body member having: an internal piston housing; and a porous membrane support mounted adjacent said piston housing having a first side adjacent to and contacting said membrane and a second side defining the upper surface of said piston housing; and a piston, sealingly engaged with said piston housing for movement from a first position to a second position within said piston housing to create a zone of reduced pressure below said porous membrane support to facilitate passage of liquid through said porous membrane support.
Claim 3
Dependent Claim
28 words
The apparatus of claim 1 further comprising means for externally manipulating said piston said means comprises a pair of oppositely disposed piston handles, extending through the body member.
Claim 4
Dependent Claim
11 words
The apparatus of claim 1 wherein the piston is molded plastic.
Claim 5
Dependent Claim
22 words
The apparatus of claim 1 wherein said membrane support is a filter member having a support surface supported within said body member.
Claim 6
Dependent Claim
16 words
The apparatus of claim 4 wherein said member is in intimate contact with said support surface.
Claim 7
Dependent Claim
49 words
The apparatus of claim 5 wherein said means comprises a cap mated to said body member, having an upward extension beyond the surface of said filter member, forming a depression for receiving a volume of the fluid to be tested, with the membrane forming the bottom of said depression.
Claim 8
Dependent Claim
12 words
The apparatus of claim 5 wherein said support surface is slightly convex.
Claim 9
Dependent Claim
23 words
The apparatus of claim 5 further comprising specific compound is an antigen and said component reactive with the specific compound is an antibody.
Claim 10
Dependent Claim
10 words
The apparatus of claim 8 wherein the antibody is anti-hCG.
Claim 11
Independent Claim
169 words
An apparatus for testing comprising: a porous member having a first surface and a second surface; a membrane having at least one antibody bound to the membrane, and positioned in intimate contact with the first surface of said porous member; a body member having: an internal piston housing; a means for mounting the porous member within the body member, the second surface of said porous member defining the upper surface of said piston housing; a piston sealingly engaged for movement from a first position to a second position within said piston housing to create a zone of reduced pressure below said porous member to facilitate the passage of liquid through the porous member; a cap mated to said body securing said membrane across said first surface of said porous member, having an upward extension beyond the level of said first surface forming a depression for receiving a volume of a fluid suspected of containing an antigen reactive with said antibody with the membrane forming the bottom of the depression.
Claim 12
Independent Claim
169 words
An apparatus for testing comprising: a porous member having a first surface and a second surface; a membrane having at least one antibody bound to the membrane, and positioned in intimate contact with the first surface of said porous member; a body member having: an internal piston housing; a means for mounting the porous member within the body member, the second surface of said porous member defining the upper surface of said piston housing; a piston sealingly engaged for movement from a first position to a second position within said piston housing to create a zone of reduced pressure below said porous member to facilitate the passage of liquid through the porous member; a cap mated to said body securing said membrane across said first surface of said porous member, having an upward extension beyond the level of said first surface forming a depression for receiving a volume of a fluid suspected of containing an antigen reactive with said antibody with the membrane forming the bottom of the depression.
Claim 13
Dependent Claim
16 words
The apparatus of claim 10 wherein said cap is mated by snap fit to said body.
Claim 14
Dependent Claim
32 words
The apparatus of claim 10 wherein said membrane has at least two antibodies bound thereto, a first for testing the viability of the reagents and a second for reacting with an antigen.
Claim 15
Dependent Claim
12 words
The apparatus of claim 10 wherein said body member is substantially cylindrical.
Claim 16
Dependent Claim
33 words
The apparatus of claim 10 wherein the piston has a molded base plate having handles extending outwardly therefrom, and a centrally positioned circumferal wall extending upwardly, terminating in a peripheral lip extending outwardly.
Claim 17
Dependent Claim
28 words
The apparatus of claim 10 wherein said body has two slots disposed on opposite sides of said body, and said piston having two handles, extending through the slots.
Claim 18
Dependent Claim
26 words
The apparatus of claim 15 wherein said slots have means for retaining said handles when said handles are depressed to the bottom of said body member.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1992-01-10 | 1992-07-11 | 1993-01-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1996-01-10 | 1996-07-11 | 1997-01-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2000-01-10 | 2000-07-11 | 2001-01-10 | $7700.00 | Window Closed / Lapsed |