US4784991A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Heavy metal salts of hyaluronic acid and their use as antimicrobial agents
Assignee: Savient Pharmaceuticals Inc
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Filing: 1987-03-09
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Granted: 1988-11-15
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Expires: 2007-03-09
Abstract
Abstract Heavy metal salts of hyaluronic acid have been prepared. In particular, this invention is directed to silver, gold, cerium and tungsten salts of hyaluronic acid. These heavy metal salts of hyaluronic acid are useful as antimicrobial agents. Gold hyaluronate may also be used to treat arthritis. This invention also concerns methods of making the silver salt of hyaluronic acid as well as compositions containing silver hyaluronate or gold hyaluronate. The invention also concerns composition containing heavy metal salts having radioactively labelled hyaluronate moieties.
Inventors
- 👤 Abraham Nimrod
- 👤 Benjamin Greenman
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 14:31
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/70; A61K31/715; A01; A01N; A01N43/00; A01N43/02; A01N43/04; A01N43/14; A01N43/16; C; C08; C08B; C08B37/00; C08B37/006; C08B37/0063; C08B37/0072
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
29 words
A method of treating a subject having keratitis which method comprises topically applying to an infection causing the keratitis an effective amount of a silver salt of hyaluronic acid.
Claim 2
Independent Claim
29 words
A method of treating a subject having keratitis which method comprises topically applying to an infection causing the keratitis an effective amount of a silver salt of hyaluronic acid.
Claim 3
Dependent Claim
19 words
A method of claim 1, wherein an antibiotic is used in conjunction with the silver salt of hyaluronic acid.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-11-15 | 1992-05-16 | 1992-11-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-11-15 | 1996-05-16 | 1996-11-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-11-15 | 2000-05-16 | 2000-11-15 | $7700.00 | Window Closed / Lapsed |