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Vessel and prosthesis impregnated with diisocyanate crosslinked gelatin

Assignee: Intermedicat GmbH
•
Filing: 1987-03-03
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Granted: 1988-11-15
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Expires: 2007-03-03
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Abstract

Abstract The invention relates to vessel prostheses formed from a porous vascular prosthesis impregnated with diisocyanate crosslinked gelatin for sealing the pores.

Inventors

  • 👤 Peter Fleckenstein
  • 👤 Heinz-Helmut Werner

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 14:31
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/507; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/28; A61L27/34; Y; Y10; Y10S; Y10S128/00; Y10S128/08; Y10S623/00; Y10S623/901; Y10S623/92; Y10S623/921; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31551; Y10T428/31565

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 51 words
An implantable vessel prosthesis comprising a porous tubular structure sealed by impregnation with a material containing gelatin which is crosslinked with a diisocyanate so that pores of the structure are filled with an insoluble crosslinked gelatin/diisocyanate decomposable at a rate of tissue growth into the pores on implantation of the prosthesis.
Claim 2
Dependent Claim 51 words
An implantable vessel prosthesis comprising a porous tubular structure sealed by impregnation with a material containing gelatin which is crosslinked with a diisocyanate so that pores of the structure are filled with an insoluble crosslinked gelatin/diisocyanate decomposable at a rate of tissue growth into the pores on implantation of the prosthesis.
Claim 3
Dependent Claim 15 words
The vessel prosthesis defined in claim 1 wherein said tubular structure is a textile structure.
Claim 4
Dependent Claim 33 words
The vessel prosthesis defined in claim 1 wherein portions of the tubular structure bounding the pores are coated with a thin film of crosslinked gelatin and the pores are closed by gelatin membranes.
Claim 5
Dependent Claim 23 words
The vessel prosthesis defined in claim 1 wherein the weight ratio of the tubular structure to the impregnating material is 1:0.2 to 1:3.
Claim 6
Dependent Claim 15 words
The vessel prosthesis defined in claim 1 wherein the impregnating material contains a hydrophilic plasticizer.
Claim 7
Dependent Claim 20 words
The vessel prosthesis defined in claim 1 wherein the impregnating material contains 10 to 30 % by weight of water.
Claim 8
Dependent Claim 14 words
The vessel prosthesis defined in claim 1 wherein the diisocyanate is an aliphatic diisocyanate.
Claim 9
Dependent Claim 18 words
The vessel prosthesis defined in claim 1, wherein the impregnating material includes at least one therapeutically active material.
Claim 10
Dependent Claim 16 words
The vessel prosthesis defined in claim 8 wherein the impregnating material contains constituents with exchanger characteristics.
Claim 11
Dependent Claim 21 words
The vessel prosthesis according to claim 8 wherein the therapeutical active material is incorporated in a manner producing a delayed-release effect.

References Cited (Backward Citations)

US3057782A Cited
US3106483A Cited
US4464468A Cited
US4060081A Cited
US4167045A Cited
GB2153235A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-11-15 1992-05-16 1992-11-15 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-11-15 1996-05-16 1996-11-15 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-11-15 2000-05-16 2000-11-15 $7700.00 Window Closed / Lapsed

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