US4784157A — Method and apparatus for taking samples from or a…

Claim 1

Independent Claim 149 words

A method of taking a plurality of blood samples from a blood vessel of a patient, using a like plurality of syringes therefor, said method comprising: (a) connecting a manifold to said blood vessel; (b) pumping at a slow rate anticoagulant through said manifold into said blood vessel; (c) interrupting pumping step (b) and then drawing from said patient into said manifold at a rapid rate blood for said sampling; (d) actuating a separate one of said plurality of syringes to remove from said manifold a sampling of blood; (e) discontinuing the actuation of each such syringe prior to the complete filling thereof with blood; (f) then flushing said manifold of blood by pumping therein at a rapid rate anticoagulant; (g) then reactuating the partially filled syringe to draw from said manifold anticoagulant; and (h) then returning to step (b) to operate another syringe to take another blood sample.

Claim 2

Independent Claim 149 words

A method of taking a plurality of blood samples from a blood vessel of a patient, using a like plurality of syringes therefor, said method comprising: (a) connecting a manifold to said blood vessel; (b) pumping at a slow rate anticoagulant through said manifold into said blood vessel; (c) interrupting pumping step (b) and then drawing from said patient into said manifold at a rapid rate blood for said sampling; (d) actuating a separate one of said plurality of syringes to remove from said manifold a sampling of blood; (e) discontinuing the actuation of each such syringe prior to the complete filling thereof with blood; (f) then flushing said manifold of blood by pumping therein at a rapid rate anticoagulant; (g) then reactuating the partially filled syringe to draw from said manifold anticoagulant; and (h) then returning to step (b) to operate another syringe to take another blood sample.

Claim 3

Dependent Claim 28 words

The method of claim 1 wherein the anticoagulant being pumped through said manifold into said blood vessel is pumped at a perfusion rate about two milliliters per hour.

Claim 4

Dependent Claim 35 words

A method according to claim 1 wherein the flushing of said manifold of blood by pumping therein at a rapid rate anticoagulant is carried out at a perfusion rate of about 20 milliliters per hour.

Claim 5

Dependent Claim 30 words

The method according to claim 3 wherein the anticoagulant is pumped through said manifold into said blood vessel during step (b) at a rate of about two milliliters per hour.

Claim 6

Dependent Claim 137 words

Apparatus for taking a blood sample comprising a manifold, means for connecting said manifold to a blood vessel of a patient, a syringe connected to said manifold for drawing a blood sample therefrom and fluid flow means operatively connected to the manifold for drawing blood into the manifold before sampling and for flushing said manifold afterwards with anticoagulant liquid, wherein said fluid flow means includes a reservoir for anticoagulant liquid and a reversible pump therefor, said apparatus further comprising control means for controlling the reversible pump and syringe so that before sampling blood with the syringe the reversible pump slowly pumps anticoagulant liquid into the patient, during sampling with the syringe the reversible pump rapidly pumps blood into the manifold, and after sampling blood with the syringe the reversible pump flushes the manifold rapidly with anticoagulant liquid.

Claim 7

Dependent Claim 137 words

Apparatus for taking a blood sample comprising a manifold, means for connecting said manifold to a blood vessel of a patient, a syringe connected to said manifold for drawing a blood sample therefrom and fluid flow means operatively connected to the manifold for drawing blood into the manifold before sampling and for flushing said manifold afterwards with anticoagulant liquid, wherein said fluid flow means includes a reservoir for anticoagulant liquid and a reversible pump therefor, said apparatus further comprising control means for controlling the reversible pump and syringe so that before sampling blood with the syringe the reversible pump slowly pumps anticoagulant liquid into the patient, during sampling with the syringe the reversible pump rapidly pumps blood into the manifold, and after sampling blood with the syringe the reversible pump flushes the manifold rapidly with anticoagulant liquid.

Claim 8

Dependent Claim 13 words

The apparatus of claim 5 wherein the reversible pump is a peristaltic pump.

Claim 9

Dependent Claim 21 words

The apparatus of claim 5 wherein the reservoir has a self-sealing cap to permit refilling of the reservoir with anticoagulant liquid.

Claim 10

Dependent Claim 13 words

The apparatus of claim 7 wherein the reversible pump is a peristaltic pump.

Claim 11

Dependent Claim 143 words

Apparatus for taking a blood sample comprising a manifold which is adapted to receive a blood sampling syringe, means for connecting said manifold to a blood vessel of a patient, and fluid flow means operatively connected to the manifold for drawing blood into the manifold before sampling and for flushing said manifold afterwards with anticoagulant liquid, wherein said fluid flow means includes a reservoir for anticoagulant liquid and a reversible pump therefor, said apparatus further comprising control means for controlling the reversible pump and the syringe when a syringe is connected to the manifold so that before sampling blood with the syringe the reversible pump slowly pumps anticoagulant liquid into the patient, during sampling with the syringe the reversible pump rapidly pumps blood into the manifold, and after sampling blood with the syringe the reversible pump flushes the manifold rapidly with anticoagulant liquid.

Claim 12

Dependent Claim 143 words

Apparatus for taking a blood sample comprising a manifold which is adapted to receive a blood sampling syringe, means for connecting said manifold to a blood vessel of a patient, and fluid flow means operatively connected to the manifold for drawing blood into the manifold before sampling and for flushing said manifold afterwards with anticoagulant liquid, wherein said fluid flow means includes a reservoir for anticoagulant liquid and a reversible pump therefor, said apparatus further comprising control means for controlling the reversible pump and the syringe when a syringe is connected to the manifold so that before sampling blood with the syringe the reversible pump slowly pumps anticoagulant liquid into the patient, during sampling with the syringe the reversible pump rapidly pumps blood into the manifold, and after sampling blood with the syringe the reversible pump flushes the manifold rapidly with anticoagulant liquid.

Claim 13

Dependent Claim 13 words

The apparatus of claim 9 wherein the reversible pump is a peristaltic pump.

Claim 14

Dependent Claim 21 words

The apparatus of claim 9 wherein the reservoir has a self-sealing cap to permit refilling of the reservoir with anticoagulant liquid.

Claim 15

Dependent Claim 13 words

The apparatus of claim 11 wherein the reversible pump is a peristaltic pump.

Claim 16

Independent Claim 127 words

A method of taking a blood sample comprising: (a) connecting a manifold to a blood vessel of a patient; (b) drawing blood from the patient into the manifold for sampling; (c) drawing a blood sample from said manifold with a syringe; and (d) flushing said manifold with anticoagulant after taking said blood sample; wherein, before blood sampling steps (b) and (c), anticoagulant liquid is pumped slowly into the patient; during step (b), the blood is drawn rapidly from the patient's blood vessel into the manifold; and wherein flushing is carried out immediately after blood sampling steps (b) and (c) by pumping at a rapid rate anticoagulant into the manifold to displace the blood therein, and after said flushing anticoagulant liquid is again pumped slowly into the patient.

Claim 17

Independent Claim 127 words

A method of taking a blood sample comprising: (a) connecting a manifold to a blood vessel of a patient; (b) drawing blood from the patient into the manifold for sampling; (c) drawing a blood sample from said manifold with a syringe; and (d) flushing said manifold with anticoagulant after taking said blood sample; wherein, before blood sampling steps (b) and (c), anticoagulant liquid is pumped slowly into the patient; during step (b), the blood is drawn rapidly from the patient's blood vessel into the manifold; and wherein flushing is carried out immediately after blood sampling steps (b) and (c) by pumping at a rapid rate anticoagulant into the manifold to displace the blood therein, and after said flushing anticoagulant liquid is again pumped slowly into the patient.

Claim 18

Dependent Claim 41 words

A method as claimed in claim 13, wherein the syringe is activated twice for drawing a sample, once to collect the blood sample without completely filling the syringe with blood and a second time to aspirate anticoagulant liquid into the syringe.

Claim 19

Dependent Claim 162 words

Apparatus for taking blood samples from an ambulatory patient, said apparatus including housing means adapted to be carried on the patient, and further including: a manifold for connection with the patient, a plurality of syringes for successively drawing blood from said manifold, and fluid flow means for drawing blood into the manifold before sampling and for flushing it afterwards with anticoagulant liquid, wherein the fluid flow means includes a reservoir for anticoagulant liquid, a reversible pump therefor and control means for controlling the pump and syringes, so that the pump (a) between samples pumps anticoagulant liquid into the patients blood vessel, (b) pumps blood into the manifold for each successive sampling of blood, and (c) after each said sampling flushes the manifold with said anticoagulant liquid, wherein the control means further activates in sequence said syringes to collect samples from the manifold when blood is present therein, and wherein the manifold, syringes and fluid flow means are housed in said housing means.

Claim 20

Dependent Claim 162 words

Apparatus for taking blood samples from an ambulatory patient, said apparatus including housing means adapted to be carried on the patient, and further including: a manifold for connection with the patient, a plurality of syringes for successively drawing blood from said manifold, and fluid flow means for drawing blood into the manifold before sampling and for flushing it afterwards with anticoagulant liquid, wherein the fluid flow means includes a reservoir for anticoagulant liquid, a reversible pump therefor and control means for controlling the pump and syringes, so that the pump (a) between samples pumps anticoagulant liquid into the patients blood vessel, (b) pumps blood into the manifold for each successive sampling of blood, and (c) after each said sampling flushes the manifold with said anticoagulant liquid, wherein the control means further activates in sequence said syringes to collect samples from the manifold when blood is present therein, and wherein the manifold, syringes and fluid flow means are housed in said housing means.

Claim 21

Dependent Claim 28 words

Apparatus as claimed in claim 15, wherein after sampling by each such syringe, said last activated syringe is again activated to draw in anticoagulant liquid from the manifold.

Claim 22

Dependent Claim 20 words

Apparatus as claimed in claim 15 further comprising means for injecting fluid into said patient for treatment of the patient.

Claim 23

Dependent Claim 125 words

A method of taking a plurality of blood samples from an ambulatory patient using the apparatus of claim 15, comprising: connecting the manifold to a blood vessel of said patient; activating the series of syringes in succession at predetermined intervals of time to draw samples from the manifold; and drawing blood from the patient into the manifold before sampling and flushing said manifold after blood sampling with anticoagulant liquid, wherein between samples anticoagulant liquid is pumped slowly into the vein; immediately before each sampling, blood is drawn rapidly from the vein into the manifold; and immediately after each sampling anticoagulant liquid is pumped into the manifold to pump the liquid in the manifold into the patient to displace the blood in the manifold with anticoagulant.

Claim 24

Dependent Claim 32 words

A method as claimed in claim 18, wherein after each sampling, the syringe last employed for blood sampling is again activated to draw in anticoagulant liquid from the manifold into the syringe.

Claim 25

Dependent Claim 42 words

A method as claimed in claim 18, further including the step of at least after one sampling injecting fluid for treatment of the patient into the liquid in the manifold prior to said liquid in the manifold being pumped into the patient.

Annuity Stage	Window Opens	Payment Deadline	Surcharge Period Until	Estimated Fee	Status
3.5 Years (Year 4)	1991-11-15	1992-05-16	1992-11-15	$2000.00	Window Closed / Lapsed
7.5 Years (Year 8)	1995-11-15	1996-05-16	1996-11-15	$3760.00	Window Closed / Lapsed
11.5 Years (Year 12)	1999-11-15	2000-05-16	2000-11-15	$7700.00	Window Closed / Lapsed

Method and apparatus for taking samples from or administering medication to a patient

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