US4776334A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Catheter for treatment of tumors
Assignee: Leland Stanford Junior University
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Filing: 1987-03-03
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Granted: 1988-10-11
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Expires: 2007-03-03
Abstract
Abstract A catheter for use in treating tumors is flexible and relatively small in diameter so that it can be inserted interstitially into the tumor mass. A conductor is provided about a length of the catheter and is electrically insulated except for a small length or small lengths thereof which are adapted to be received within the tumor volume. By connecting the conductor to a high frequency power source a heat producing current can be generated through the tumor tissue adjacent the exposed portions of the catheter to damage the tumor cells. One or more temperature sensing devices are included in the catheter and are located adjacent to the exposed conductor or conductors for monitoring the temperature of the adjacent tumor tissue. The signals from these devices, which are picked up from a connector at one end of the catheter, can then be used to control the current to the conductor or conductors so as to maintain the tumor volume at a constant and uniform desired temperature.
Inventors
- 👤 Stavros D. Prionas
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 20:26
CPC Classifications
A; A61; A61B; A61B18/00; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B17/00; A61B2017/00017; A61B2017/00022; A61B2017/00084; A61B2017/00092; A61B2017/00101; A61B17/00234; A61B2017/00292
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
163 words
A catheter for use in treating tumors or the like within the body of a patient comprising an elongate flexible supporting member of a size and flexibility adapting it to be interstitially implanted in the patient, a plurality of conductors provided about said supporting member in spaced positions along a predetermined length of the supporting member adapted to correspond to the length of the catheter passage through the tumor to be treated, means for individually connecting each of said conductors to a source of high frequency current, electrical insulation extending about said supporting member over the length thereof and between said conductors to leave only said conductors exposed to permit conduction of current therefrom through the tissue of the patient, and means for separately sensing the temperature at each of said conductors and for providing signals indicative thereof whereby each of said conductors can be monitored and the power delivered thereto adjusted so as to provide a continuous uniform temperature through said tumor.
Claim 2
Dependent Claim
163 words
A catheter for use in treating tumors or the like within the body of a patient comprising an elongate flexible supporting member of a size and flexibility adapting it to be interstitially implanted in the patient, a plurality of conductors provided about said supporting member in spaced positions along a predetermined length of the supporting member adapted to correspond to the length of the catheter passage through the tumor to be treated, means for individually connecting each of said conductors to a source of high frequency current, electrical insulation extending about said supporting member over the length thereof and between said conductors to leave only said conductors exposed to permit conduction of current therefrom through the tissue of the patient, and means for separately sensing the temperature at each of said conductors and for providing signals indicative thereof whereby each of said conductors can be monitored and the power delivered thereto adjusted so as to provide a continuous uniform temperature through said tumor.
Claim 3
Dependent Claim
26 words
A catheter as set forth in claim 1 wherein said means for connecting comprises conductive leads embedded within said flexible supporting member and extending longitudinally thereof.
Claim 4
Dependent Claim
37 words
A catheter as set forth in claim 1 wherein said means for sensing comprises a plurality of temperature sensing elements positioned adjacent to said conductors and electrical leads extending from each of said elements along said insulation.
Claim 5
Dependent Claim
88 words
A catheter according to claim 1 wherein there are provided a plurality of said conductors arranged at longitudinally spaced positions along said catheter and a plurality of means for individually connecting the conductors to a source of high frequency current, said insulation serving to space said conductors from each other and from exposure for a predetermined distance from said one end of the catheter, and a plurality of said temperature sensing means for separately sensing the temperature of the tissue of the patient adjacent each exposed conductor portion.
Claim 6
Dependent Claim
176 words
A catheter for use in treating tumors or the like within the body of a patient, comprising: an elongate supporting member adapted to be interstitially implanted in the patient, a plurality of conductive wires wound about the axis of the supporting member including one set of wires wound in one direction about the supporting member, and a second set of wires wound in the other direction, each set including at least two wires, at least one wire of each set being joined to one wire of the other to form a thermocouple, temperature sensing means comprising at least one of the wires being joined to another of the wires at a temperature sensing position, the joined wires being made of different materials to form said thermocouple at their juncture, and an insulating layer extending over the conductive wires for a portion of the length of the catheter, with another portion of the catheter being free of insulation to expose the wires and form a tumor heating portion, said thermocouple being associated with the tumor heating portion.
Claim 7
Dependent Claim
176 words
A catheter for use in treating tumors or the like within the body of a patient, comprising: an elongate supporting member adapted to be interstitially implanted in the patient, a plurality of conductive wires wound about the axis of the supporting member including one set of wires wound in one direction about the supporting member, and a second set of wires wound in the other direction, each set including at least two wires, at least one wire of each set being joined to one wire of the other to form a thermocouple, temperature sensing means comprising at least one of the wires being joined to another of the wires at a temperature sensing position, the joined wires being made of different materials to form said thermocouple at their juncture, and an insulating layer extending over the conductive wires for a portion of the length of the catheter, with another portion of the catheter being free of insulation to expose the wires and form a tumor heating portion, said thermocouple being associated with the tumor heating portion.
Claim 8
Dependent Claim
32 words
A catheter according to claim 5 wherein a plurality of thermocouples are formed across the exposed portion by joining selected wires from the first set to selected wires from the second set.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-10-11 | 1992-04-11 | 1992-10-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-10-11 | 1996-04-11 | 1996-10-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-10-11 | 2000-04-11 | 2000-10-11 | $7700.00 | Window Closed / Lapsed |