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US4774329A Expired / Lapsed US ⏱️ 0.0 years remaining

Controlled release agent for cetylpyridinium chloride

Assignee: Cerestar USA Inc
•
Filing: 1987-08-04
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Granted: 1988-09-27
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Expires: 2007-08-04
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Abstract

Abstract A complex of cyclodextrin and cetylpyridinium chloride is disclosed as a controlled release agent of cetylpyridinium chloride. The cyclodextrin can be either cyclodextrin molecule, a polymer of cyclodextrin or modified cyclodextrin. The method of forming the complex is also disclosed.

Inventors

  • 👤 Robert B. Friedman

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 18:25
CPC Classifications
B; B82; B82Y; B82Y5/00; A; A61; A61K; A61K47/00; A61K47/50; A61K47/69; A61K47/6949; A61K47/6951; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; C; C08; C08B; C08B37/00; C08B37/0006; C08B37/0009; C08B37/0012; C08B37/0015

Claims Analysis

Total Claims: 13
Claim 1
Independent Claim 16 words
A controlled release agent for cetylpyridinium chloride comprising a complex formed between cyclodextrin and cetylpyridinium chloride.
Claim 2
Dependent Claim 16 words
A controlled release agent for cetylpyridinium chloride comprising a complex formed between cyclodextrin and cetylpyridinium chloride.
Claim 3
Dependent Claim 14 words
The controlled release agent of claim 1 wherein the cyclodextrin is a beta cyclodextrin.
Claim 4
Dependent Claim 31 words
The controlled release agent of claim 1 wherein the cyclodextrin is produced by reaction of cyclodextrin with a crosslinking agent or by reaction of cyclodextrin with a previously formed polymer backbone.
Claim 5
Dependent Claim 37 words
The controlled release agent of claim 1 wherein the cyclodextrin has been modified in a manner such that the cavity of the cyclodextrin is not too restricted or capped to prevent complex formation with said cetylpyridinium chloride.
Claim 6
Independent Claim 46 words
A method for making a controlled release agent for cetylpyridinium chloride comprising the steps of: (a) mixing cyclodextrin and cetylpyridinium chloride together in water for a sufficient period of time to form a complex; (b) recovering said complex from water; and (c) drying said recovered complex.
Claim 7
Independent Claim 46 words
A method for making a controlled release agent for cetylpyridinium chloride comprising the steps of: (a) mixing cyclodextrin and cetylpyridinium chloride together in water for a sufficient period of time to form a complex; (b) recovering said complex from water; and (c) drying said recovered complex.
Claim 8
Dependent Claim 12 words
The method of claim 5 wherein the cyclodextrin is a beta cyclodextrin.
Claim 9
Dependent Claim 29 words
The method of claim 5 wherein the cyclodextrin is produced by reaction of cyclodextrin with a cross-linking agent or by reaction of cyclodextrin with a previously formed polymer backbone.
Claim 10
Dependent Claim 35 words
The method of claim 5 wherein the cyclodextrin has been modified in a manner such that the cavity of the cyclodextrin is not too restricted or capped to prevent complex formation with said cetylpyridinium chloride.
Claim 11
Dependent Claim 30 words
The method of claim 5 wherein the temperature is about 85° C. during the mixing step and the period of time sufficient to form the complex is about 12 hours.
Claim 12
Dependent Claim 30 words
The method of claim 7 wherein the temperature during the mixing step is about room temperature and the period of time sufficient to form the complex is about 3 hours.
Claim 13
Dependent Claim 31 words
The method of claim 5 wherein the amount of cetylpyridinium chloride and cyclodextrin is in a ratio of about 0.5:1 to about 4:1 of moles of cetylpyridinium chloride:moles of cyclodextrin molecule.

References Cited (Backward Citations)

US3420789A Cited
US3472835A Cited
US4274985A Cited
US4357468A Cited
US4472373A Cited
US4576950A Cited
US4727064A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-09-27 1992-03-28 1992-09-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-09-27 1996-03-28 1996-09-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-09-27 2000-03-28 2000-09-27 $7700.00 Window Closed / Lapsed

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