US4772285A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Collagen coated soft tissue prostheses
Assignee: Leland Stanford Junior University
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Filing: 1986-10-30
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Granted: 1988-09-20
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Expires: 2006-10-30
Abstract
Abstract An improved soft tissue implant which resists capsule formation and contracture is described. The implant is coated with a non-immunogenic collagen preparation optionally stabilized by crosslinking.
Inventors
- 👤 George Ksander
- 👤 Leonard Gray
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:59
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; A61F; A61F2/00; A61F2/0059; A61F2/02; A61F2/12; Y; Y10; Y10S; Y10S128/00; Y10S128/08
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
38 words
An improved breast implant which is resistant to encapsulation comprising an alloplastic breast prosthesis encased in an integral coating consisting essentially of atelopeptide collagen, wherein said integral coating directly adheres the solid surface of said alloplastic breast prosthesis.
Claim 2
Dependent Claim
38 words
An improved breast implant which is resistant to encapsulation comprising an alloplastic breast prosthesis encased in an integral coating consisting essentially of atelopeptide collagen, wherein said integral coating directly adheres the solid surface of said alloplastic breast prosthesis.
Claim 3
Dependent Claim
10 words
The implant of claim 1 wherein the collagen is reconstituted.
Claim 4
Dependent Claim
14 words
The implant of claim 1 wherein the alloplastic prosthesis is a silicone gel prosthesis.
Claim 5
Dependent Claim
11 words
The implant of claim 1 wherein the collagen coating is crosslinked.
Claim 6
Dependent Claim
14 words
The implant of claim 4 wherein the crosslinking is effected by fomaldehyde or glutaraldehyde.
Claim 7
Independent Claim
41 words
A method of making a breast implant resistant to encapsulation comprising coating an alloplastic breast prosthesis with reconstituted atelopeptide collagen, whereby said reconstituted atelopeptide collagen forms an integral coating that directly adheres to the solid surface of said alloplastic breast prosthesis.
Claim 8
Independent Claim
41 words
A method of making a breast implant resistant to encapsulation comprising coating an alloplastic breast prosthesis with reconstituted atelopeptide collagen, whereby said reconstituted atelopeptide collagen forms an integral coating that directly adheres to the solid surface of said alloplastic breast prosthesis.
Claim 9
Dependent Claim
10 words
The method of claim 6 wherein the collagen is reconstituted.
Claim 10
Dependent Claim
13 words
The method of claim 6 wherein the alloplastic prosthesis is a silicone prosthesis.
Claim 11
Dependent Claim
14 words
The method of claim 6 which includes the step of crosslinking the collagen coating.
Claim 12
Dependent Claim
14 words
The method of claim 9 wherein the crosslinking is effected by glutaraldehyde or formaldehyde.
Claim 13
Dependent Claim
15 words
The method of claim 6 wherein the collagen coating is applied in 2 sequential layers.
Claim 14
Dependent Claim
17 words
A method of supplementing mammary tissue which comprises surgical implantation of the improved prosthesis of claim 1.
Claim 15
Dependent Claim
17 words
A method of supplementing mammary tissue which comprises surgical implantation of the improved prosthesis of claim 1.
Claim 16
Dependent Claim
13 words
The implant of claim 1 wherein the alloplastic prosthesis is a silicone prosthesis.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-09-20 | 1992-03-21 | 1992-09-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-09-20 | 1996-03-21 | 1996-09-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-09-20 | 2000-03-21 | 2000-09-20 | $7700.00 | Window Closed / Lapsed |