3-(acylaminomethyl)imidazo[1,2-a]pyridine derivatives and pharmaceutical compositions

Claim 1

A compound which is a 3-(acylaminomethyl)imidazo[1,2-a]pyridine derivative of formula (I) ##STR8## in which R 1 denotes hydrogen; linear or branched C 1 -C 4 alkyl; or benzyl: R 2 denotes linear or branched C 1 -C 6 alkyl; cyclohexyl; trichloromethyl; 1-propenyl; allyl; phenyl; 4-chlorophenyl; or benzyl: or R 1 and R 2 together denote a C 3 -C 5 aliphatic chain: X denotes halogen; C 1 -C 3 alkyl; methylthio; trifluoromethyl; optionally esterified carboxy of formula --COOR in which R denotes hydrogen or C 1 -C 6 alkyl; cyano; or optionally mono- or dialkylated aminocarbonyl of formula --CONR 3 R 4 in which R 3 and R 4 independently denote hydrogen or C 1 -C 4 alkyl or together denote a chain of formula --(CH 2 ) 2 --Z--(CH 2 ) 2 -- in which Z denotes a direct bond, oxygen, sulphur, or a divalent group of formula --CH 2 --, --NH-- or --N(C 1 -C 4 alkyl)--; alkylamino of formula NHR 5 in which R 5 denotes C 2 -C 6 alkyl; or dialkylamino of formula --NR 6 R 7 in which R 6 and R 7 independently denote C 2 -C 6 alkyl or together denote a chain of formula --(CH 2 ) 2 --Z--(CH 2 ) 2 -- in which Z denotes a direct bond, oxygen, sulphur, or a divalent group of formula --CH 2 --, --NH-- or --N(C 1 -C 4 alkyl)--: and Y denotes optionally esterified carboxy of formula --COOR 8 in which R 8 denotes hydrogen or C 1 -C 6 alkyl; cyano; or optionally mono- or dialkylated aminocarbonyl of formula --CONR 9 R 10 in which R 9 and R 10 independently hydrogen or C 1 -C 4 alkyl; or a pharmacologically acceptable acid addition salt.