US4767746A
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Method for enhancement of healing of epithelial wounds in mammals
Assignee: ANGIO-MEDICAL Corp A CORP OF DE
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Filing: 1985-12-04
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Granted: 1988-08-30
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Expires: 2005-12-04
Abstract
Abstract Omental lipid fractions accelerate wound healing especially as to epithelialization in mammals.
Inventors
- 👤 Nicholas Catsimpoolas
- 👤 Robert S. Sinn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 22:14
CPC Classifications
A; A61; A61K; A61K38/00; A61K31/00; A61K35/00; A61K35/12; A61K35/37; Y; Y10; Y10S; Y10S424/00; Y10S424/13
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
35 words
Method for enhanced wound epithelialization in mammals having epithelial wounds which comprises: treating epithelial wounds systemically or topically with pharmacologically active doses of mammalian omental lipid fractions capable of promoting angiogenic activity and comprising ganglioside.
Claim 2
Dependent Claim
35 words
Method for enhanced wound epithelialization in mammals having epithelial wounds which comprises: treating epithelial wounds systemically or topically with pharmacologically active doses of mammalian omental lipid fractions capable of promoting angiogenic activity and comprising ganglioside.
Claim 3
Dependent Claim
13 words
Method of claim 1 wherein the pharmacologically active angiogenic material further comprises triglyceride.
Claim 4
Dependent Claim
9 words
Method of claim 1 further comprising an anti-bacterial effect.
Claim 5
Dependent Claim
9 words
Method of claim 3 further comprising a fungicidal effect.
Claim 6
Dependent Claim
39 words
Method for enhanced wound epithelializaiton in mammals having epithelial wounds which comprises: treating epithelial wounds systemically or topically with pharmacologically active doses of mammalian omental lipid fractions capable of promoting angiogenic activity and consisting essentially of lipids comprising triglyceride.
Claim 7
Dependent Claim
39 words
Method for enhanced wound epithelializaiton in mammals having epithelial wounds which comprises: treating epithelial wounds systemically or topically with pharmacologically active doses of mammalian omental lipid fractions capable of promoting angiogenic activity and consisting essentially of lipids comprising triglyceride.
Claim 8
Dependent Claim
25 words
Method of claim 1, 2 or 5 wherein the pharmacologically active angiogenic omental lipid fraction is obtained by extraction with at least one organic solvent.
Claim 9
Dependent Claim
11 words
Method of claim 6 wherein the extraction is a chloroform-methanol extraction.
Claim 10
Dependent Claim
18 words
Method of claim 7 wherein the pharmacologically active lipid fraction is a hexane extract of the chloroform-methanol fraction.
Claim 11
Dependent Claim
22 words
Method of claim 1, 2 or 5 wherein the pharmacologically active angiogenic omental lipid fraction is a supercritical gas extract of omentum.
Claim 12
Dependent Claim
13 words
Method of claim 1, 2, or 5 for treatment of autologous skin grafts.
Claim 13
Dependent Claim
21 words
Composition from mammalian omentum for enhancing wound healing and epithelialization comprising a mammlaian omental lipid fraction consisting essentially of isolated ganglioside.
Claim 14
Dependent Claim
21 words
Composition from mammalian omentum for enhancing wound healing and epithelialization comprising a mammlaian omental lipid fraction consisting essentially of isolated ganglioside.
Claim 15
Dependent Claim
24 words
Composition from mammalian ometum for enhancing wound healing and epithelialization comprising a mammalian omental lipid fraction wherein the lipid material comprises ganglioside and triglyceride.
Claim 16
Dependent Claim
24 words
Composition from mammalian ometum for enhancing wound healing and epithelialization comprising a mammalian omental lipid fraction wherein the lipid material comprises ganglioside and triglyceride.
Claim 17
Dependent Claim
10 words
Composition of claim 12 wherein the lipid material comprises triglyceride.
References Cited (Backward Citations)
US4476119A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-08-30 | 1992-02-29 | 1992-08-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-08-30 | 1996-02-29 | 1996-08-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-08-30 | 2000-02-29 | 2000-08-30 | $7700.00 | Window Closed / Lapsed |