US4765973A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polymers containing pendant acid functionalities and labile backbone bonds
Assignee: Merck and Co Inc
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Filing: 1986-10-06
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Granted: 1988-08-23
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Expires: 2006-10-06
Abstract
Abstract The instant invention is directed to a polymer with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units. The instant invention is also directed to a controlled release device which comprises: (A) a polymer with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units; and (B) a beneficial substance incorporated within or surrounded by the matrix of said polymer.
Inventors
- 👤 Jorge Heller
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 15:20
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2031; A61K9/204; C; C08; C08G; C08G65/00; C08G65/34; C08G85/00
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
65 words
A controlled release device which comprises: (A) a polymer selected from the group consisting of polyorthoesters, polyacetals, polyketals, polyesters and polyphosphazenes with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units; and (B) a beneficial substance capable of being released to an aqueous atmosphere incorporated within or surrounded by the matrix of said polymer.
Claim 2
Dependent Claim
65 words
A controlled release device which comprises: (A) a polymer selected from the group consisting of polyorthoesters, polyacetals, polyketals, polyesters and polyphosphazenes with at least one labile backbone bond per repeat unit and at least one pendant acid functionality per thousand repeat units; and (B) a beneficial substance capable of being released to an aqueous atmosphere incorporated within or surrounded by the matrix of said polymer.
Claim 3
Dependent Claim
24 words
The controlled release device of claim 1, wherein the pendant acid functionality is selected from the group consisting of carboxylic, phosphoric, sulfonic and sulfenic.
Claim 4
Dependent Claim
63 words
The controlled release device of claim 1, prepared from a diol containing a pendant acid functionality selected from the group consisting of 9,10-dihydroxystearic acid; 3,6-dihydroxynaphthalene 2,7-disulfonic acid; 2,4-dihydroxybenzoic acid; 3,4-dihydroxycinnamic acid; 6,7-dihydroxy-2-napthalene sulfenic acid; 6,7-dihydroxy-2-naphthalene sulfonic acid; 2,5-dihydroxyphenylacetic acid; 2,4-dihydroxypyrimidine-5-carboxylic acid; 4,8-dihydroxyquinoline-2-carboxylic acid; and mixtures thereof; and at least one additional monomer selected from the group consisting of esters, acetals and mixtures thereof.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-08-23 | 1992-02-22 | 1992-08-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-08-23 | 1996-02-22 | 1996-08-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-08-23 | 2000-02-22 | 2000-08-23 | $7700.00 | Window Closed / Lapsed |