US4760093A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Spray dried acetaminophen
Assignee: Wyeth LLC
•
Filing: 1986-10-21
•
Granted: 1988-07-26
•
Expires: 2006-10-21
Abstract
Abstract A therapeutic taste-neutral powder form of acetaminophen obtained by spray-drying a suspension of acetaminophen in a solution of a particular copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters.
Inventors
- 👤 Robert G. Blank
- 👤 Dhiraj S. Mody
- 👤 Gary R. Agism
- 👤 Richard J. Kenny
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 23:55
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1605; A61K9/1629; A61K9/1635; A61K31/00; A61K31/16; A61K31/165; A61K9/0012; A61K9/0053; A61K9/0056; A61P; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
82 words
A therapeutic taste neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 74% by weight acetaminophen and about 26% to 40% by weight of a copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters having a mean molecular weight of 150,000, the powder having been spray dried from a suspension of the acetaminophen in a solution of the copolymer in an organic solvent selective for the copolymer.
Claim 2
Dependent Claim
82 words
A therapeutic taste neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 74% by weight acetaminophen and about 26% to 40% by weight of a copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters having a mean molecular weight of 150,000, the powder having been spray dried from a suspension of the acetaminophen in a solution of the copolymer in an organic solvent selective for the copolymer.
Claim 3
Dependent Claim
116 words
In a pharmaceutical dosage form for oral administration as a solid, which dosage form can be disintegrated by water within ten seconds, the improvement which comprises incorporating into such dosage form as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 74% by weight acetaminophen and about 26% to 40% by weight of a copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters having a mean molecular weight of 150,000, the powder having been spray dried from a suspension of the acetaminophen in a solution of the copolymer in an organic solvent selective for the copolymer.
Claim 4
Dependent Claim
116 words
In a pharmaceutical dosage form for oral administration as a solid, which dosage form can be disintegrated by water within ten seconds, the improvement which comprises incorporating into such dosage form as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 74% by weight acetaminophen and about 26% to 40% by weight of a copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters having a mean molecular weight of 150,000, the powder having been spray dried from a suspension of the acetaminophen in a solution of the copolymer in an organic solvent selective for the copolymer.
Claim 5
Dependent Claim
109 words
In a pharmaceutical dosage form for oral administration as a solid chewable taste-neutral tablet containing acetaminophen, the improvement which comprises incorporating into such tablet as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 74% by weight acetaminophen and about 26% to 40% by weight of a copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters having a mean molecular weight of 150,000, the powder having been spray dried from a suspension of the acetaminophen in a solution of the copolymer in an organic solvent selective for the copolymer.
Claim 6
Dependent Claim
109 words
In a pharmaceutical dosage form for oral administration as a solid chewable taste-neutral tablet containing acetaminophen, the improvement which comprises incorporating into such tablet as the pharmaceutical substance a therapeutic taste-neutral powder form of spray-dried acetaminophen which consists essentially of, based upon the weight of the powder, about 60% to 74% by weight acetaminophen and about 26% to 40% by weight of a copolymer, cationic in character, based on dimethylaminoethyl methacrylate and neutral methacrylic acid esters having a mean molecular weight of 150,000, the powder having been spray dried from a suspension of the acetaminophen in a solution of the copolymer in an organic solvent selective for the copolymer.
Claim 7
Dependent Claim
13 words
The spray-dried acetaminophen of claim 1 wherein the organic solvent is methylene chloride.
Claim 8
Dependent Claim
14 words
The pharmaceutical dosage form of claim 2 wherein the organic solvent is methylene chloride.
Claim 9
Dependent Claim
14 words
The pharmaceutical dosage form of claim 3 wherein the organic solvent is methylene chloride.
References Cited (Backward Citations)
US4562024A
Cited
US4631284A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-26 | 1992-01-25 | 1992-07-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-26 | 1996-01-25 | 1996-07-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-26 | 2000-01-25 | 2000-07-26 | $7700.00 | Window Closed / Lapsed |