US4760071A
Expired / Lapsed
US
⏱️ 0.0 years remaining
17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
Assignee: Merck and Co Inc
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Filing: 1985-11-21
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Granted: 1988-07-26
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Expires: 2005-11-21
Abstract
Abstract This invention is for the compound 17 beta -(N-t-butylcarbamoyl)-4-aza-5 alpha -androst-1-en-3-one, pharmaceutical compositions containing the compound, methods of inhibiting testosterone 5 alpha -reductase with the compound and methods of treating hyperandrogenic conditions with the compound, particularly benign prostatic hypertrophy.
Inventors
- 👤 Gary H. Rasmusson
- 👤 Glenn F. Reynolds
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 21:06
CPC Classifications
C; C07; C07C; C07C62/00; C07C62/30; C07C62/38; C07J; C07J73/00; C07J73/001; C07J73/005; C07C2603/00; C07C2603/02; C07C2603/04; C07C2603/06; C07C2603/10; C07C2603/12; C07C2603/16
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
1 words
17β(N-t-butylcarbamoyl)-4-aza-5α-androst-1-en-3-one.
Claim 2
Dependent Claim
1 words
17β(N-t-butylcarbamoyl)-4-aza-5α-androst-1-en-3-one.
Claim 3
Dependent Claim
38 words
A method of treating the hyperandrogenic condition of acne vulgaris, seborrhea, femal hirsutism, and benign prostatic hypertrophy comprising administration to a patient in need of such treatment of a therapeutically effective amount of the compound of claim 1.
Claim 4
Dependent Claim
32 words
A method of inhibiting testosterone 5α-reductase in a patient in need of such inhibiting treatment, comprising administration to such a patient of a therapeutically effective amount of the compound of claim 1.
Claim 5
Dependent Claim
17 words
A pharmaceutical composition comprising a pharmaceutically acceptable carrier and an effective amount of the compound claim 1.
References Cited (Backward Citations)
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Cited
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Cited
US4377584A
Cited
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-26 | 1992-01-25 | 1992-07-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-26 | 1996-01-25 | 1996-07-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-26 | 2000-01-25 | 2000-07-26 | $7700.00 | Window Closed / Lapsed |