US4758433A
Expired / Lapsed
US
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Oil extract of Tanacetum parthenium for treating migraine
Assignee: Catalent Pharma Solutions Inc
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Filing: 1985-06-26
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Granted: 1988-07-19
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Expires: 2005-06-26
Abstract
Abstract A preparation for pharmaceutical use, especially in the treatment of migraine, arthritis and bronchial complaints contains a sesquiterpene lactone and is recovered from the plant Tanacetum parthenium by extraction using a pharmaceutically acceptable oil.
Inventors
- 👤 Edward S. Johnson
- 👤 Peter J. Hylands
- 👤 Deborah M. Hylands nee Jessup
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-08 02:10
CPC Classifications
C; C07; C07D; C07D493/00; C07D493/02; C07D493/04; A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/365; C07D307/00; C07D307/77; C07D307/93; C07D493/12; C07D493/14
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
109 words
A method of alleviating migraine in a human being which method comprises administering to the human being, a spasomolytically active composition comprising a solution of a spasmolitically effective amount of an extract of the plant Tanacetum parthemium in a pharmacuetically acceptable oil, comprising at least one sesquiterpene lactone and which solution is obtained by extraction of the dried said plant with the said pharmaceutically acceptable oil, the oil being selected from the group consisting of saturated and un-saturated long chain hydrocarbons and fatty acids, vegetable and animal oils and ployoxeyethylated derivatives thereof and reconstituted glycerides and esters thereof, wherein said hydrocarbon chain comprises between 10 and 25 carbon atoms.
Claim 2
Independent Claim
109 words
A method of alleviating migraine in a human being which method comprises administering to the human being, a spasomolytically active composition comprising a solution of a spasmolitically effective amount of an extract of the plant Tanacetum parthemium in a pharmacuetically acceptable oil, comprising at least one sesquiterpene lactone and which solution is obtained by extraction of the dried said plant with the said pharmaceutically acceptable oil, the oil being selected from the group consisting of saturated and un-saturated long chain hydrocarbons and fatty acids, vegetable and animal oils and ployoxeyethylated derivatives thereof and reconstituted glycerides and esters thereof, wherein said hydrocarbon chain comprises between 10 and 25 carbon atoms.
Claim 3
Dependent Claim
23 words
A method according to claim 1, wherein the oil is selected from the group consisting of coconut oil soybean oil and fish oil.
Claim 4
Dependent Claim
26 words
A method according to claim 1, which comprises administering to the human being an effective amount of an encapsulated preparation comprising the said spasomolytically active composition.
Claim 5
Dependent Claim
11 words
A method according to claim 1, wherein the extract contains parthenolide.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-07-19 | 1992-01-18 | 1992-07-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-07-19 | 1996-01-18 | 1996-07-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-07-19 | 2000-01-18 | 2000-07-19 | $7700.00 | Window Closed / Lapsed |