US4753794A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of mullerian inhibiting substance as a contraceptive agent
Assignee: General Hospital Corp
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Filing: 1986-06-24
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Granted: 1988-06-28
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Expires: 2006-06-24
Abstract
Abstract The invention discloses a novel use of Mullerian Inhibiting Substances (MIS) as a contraceptive agent. MIS has been found to inhibit the maturation of oocytes in vitro. Additionally, the invention provides a means for restoring the fertility of females who are infertile due to abnormal production of MIS.
Inventors
- 👤 Patricia Donahoe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 22:43
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/18; A61K38/1808; C; C07; C07K; C07K16/00; C07K16/18; C07K16/26; Y; Y10; Y10S; Y10S424/00; Y10S424/811
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
21 words
A method of contraception which comprises providing to a female an effective amount of a composition which comprises Mullerian Inhibiting Substance.
Claim 2
Independent Claim
21 words
A method of contraception which comprises providing to a female an effective amount of a composition which comprises Mullerian Inhibiting Substance.
Claim 3
Dependent Claim
16 words
The method of claim 1 wherein said Mullerian Inhibiting Substance is substantially free of natural contaminants.
Claim 4
Dependent Claim
24 words
The method of claim 1 wherein said Mullerian Inhibiting Substance is produced by expression of a recombinant Mullerian Inhibiting Substance gene in a host.
Claim 5
Dependent Claim
17 words
The method of claim 1 wherein said administration is by oral, local, intravenous, intramuscular or parenteral route.
Claim 6
Independent Claim
36 words
A method of inducing fertility in a female suffering from infertility caused by abnormally high levels of Mullerian Inhibiting Substance, which comprises administering to said female an effective amount of an antibody to Mullerian Inhibiting Substance.
Claim 7
Independent Claim
36 words
A method of inducing fertility in a female suffering from infertility caused by abnormally high levels of Mullerian Inhibiting Substance, which comprises administering to said female an effective amount of an antibody to Mullerian Inhibiting Substance.
Claim 8
Dependent Claim
10 words
The method of claim 5 wherein said antibody is monoclonal.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-06-28 | 1991-12-28 | 1992-06-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-06-28 | 1995-12-28 | 1996-06-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-06-28 | 1999-12-28 | 2000-06-28 | $7700.00 | Window Closed / Lapsed |