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US4753654A Expired / Lapsed US ⏱️ 0.0 years remaining

Ultraviolet radiation absorbing intraocular lens

Assignee: Ciba Vision AG
•
Filing: 1986-12-31
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Granted: 1988-06-28
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Expires: 2006-12-31
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Abstract

Abstract An intraocular lens capable of absorbing ultraviolet radiation and, additionally, a method for forming the lens is provided. The intraocular lens comprises a polymer matrix that is biocompatible with body tissue and fluids and comprises polymethylmethacrylate and a chromophoric compound. The intraocular lens preferably has about the same capability for absorbing ultraviolet radiation as does the natural crystalline lens of the eye. In one embodiment, the intraocular lens is formed by co-polymerizing a polymerizable derivate of 2,4-dihydroxybenzophenone and methyl methacrylate monomer to form an ultraviolet light absorbing co-polymer additive. The co-polymer additive is mixed with methyl methacrylate monomer for forming a prepolymer solution that is then cured. The intraocular lens is formed from the solid cured co-polymer.

Inventors

  • 👤 Thomas Posin
  • 👤 Daniel D. Lawson

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-30 05:28
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/14; A61F2/16; A61L; A61L27/00; A61L27/14; A61L27/16; A61L27/50; A61F2002/16965; A61L2430/00; A61L2430/16

Claims Analysis

Total Claims: 14
Claim 1
Independent Claim 80 words
A method for forming an intraocular lens comprising the steps of: (a) co-polymerizing by solution polymerization a polymerizable derivative of dihydroxybenzophenone and methyl methacrylate monomer to form a solid ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 2
Independent Claim 80 words
A method for forming an intraocular lens comprising the steps of: (a) co-polymerizing by solution polymerization a polymerizable derivative of dihydroxybenzophenone and methyl methacrylate monomer to form a solid ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 3
Dependent Claim 14 words
The method according to claim 1 wherein the polymerizable derivative of dihydroxybenzophenone comprises 2-hydroxy-4-(2-hydroxy-3-methacrylyloxy)propoxybenzophenone.
Claim 4
Dependent Claim 14 words
The method according to claim 1 wherein the polymerizable derivative of dihydroxybenzophenone is monofunctional.
Claim 5
Independent Claim 78 words
A method for forming an intraocular lens comprising the steps of: (a) co-polymerizing a monofunctional polymerizable derivative of dihydroxybenzophenone and methyl methacrylate monomer to form a solid ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 6
Independent Claim 78 words
A method for forming an intraocular lens comprising the steps of: (a) co-polymerizing a monofunctional polymerizable derivative of dihydroxybenzophenone and methyl methacrylate monomer to form a solid ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 7
Dependent Claim 14 words
The method according to claim 4 wherein the polymerizable derivative of dihydroxybenzophenone comprises 2-hydroxy-4-(2-hydroxy-3-methacrylyloxy)propoxybenzophenone.
Claim 8
Dependent Claim 99 words
An intraocular lens for implantation into the human eye comprising an ultraviolet radiation absorbing co-polymer physically trapped within a polymethylmethacrylate polymer matrix, said lens being formed by the steps of: (a) co-polymerizing by solution polymerization a polymerizable derivative of dihydroxybenzophenone with methyl methacrylate monomer to thereby form an ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 9
Dependent Claim 99 words
An intraocular lens for implantation into the human eye comprising an ultraviolet radiation absorbing co-polymer physically trapped within a polymethylmethacrylate polymer matrix, said lens being formed by the steps of: (a) co-polymerizing by solution polymerization a polymerizable derivative of dihydroxybenzophenone with methyl methacrylate monomer to thereby form an ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 10
Dependent Claim 21 words
An intraocular lens for implantation into the human eye according to claim 6 wherein the polymerizable derivative of dihydroxybenzophenone comprises 2-hydroxy-4-(2-hydroxy-3-methacrylyloxy)propoxybenzophenone.
Claim 11
Dependent Claim 21 words
An intraocular lens for implantation into the human eye according to claim 6 wherein the polymerizable derivative of dihydroxybenzophenone is monofunctional.
Claim 12
Dependent Claim 97 words
An intraocular lens for implantation into the human eye comprising an ultraviolet radiation absorbing co-polymer physically trapped within a polymethylmethacrylate polymer matrix, said lens being formed by the steps of: (a) co-polymerizing a monofunctional polymerizable derivative of dihydroxybenzophenone with methyl methacrylate monomer to thereby form an ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 13
Dependent Claim 97 words
An intraocular lens for implantation into the human eye comprising an ultraviolet radiation absorbing co-polymer physically trapped within a polymethylmethacrylate polymer matrix, said lens being formed by the steps of: (a) co-polymerizing a monofunctional polymerizable derivative of dihydroxybenzophenone with methyl methacrylate monomer to thereby form an ultraviolet radiation absorbing co-polymer additive; (b) dissolving the ultraviolet radiation absorbing co-polymer additive in methyl methacrylate monomer to thereby form a prepolymer solution; (c) curing the prepolymer solution in a mold to thereby form an intraocular lens comprising the ultraviolet radiation absorbing co-polymer additive physically trapped within a polymethylmethacrylate polymer matrix.
Claim 14
Dependent Claim 21 words
An intraocular lens for implantation into the human eye according to claim 9 wherein the polymerizable derivative of dihydroxybenzophenone comprises 2-hydroxy-4-(2-hydroxy-3-methacrylyloxy)propoxybenzophenone.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-06-28 1991-12-28 1992-06-28 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-06-28 1995-12-28 1996-06-28 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-06-28 1999-12-28 2000-06-28 $7700.00 Window Closed / Lapsed

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