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US4749722A Expired / Lapsed US ⏱️ 0.0 years remaining

Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs

Assignee: Analgesic Associates
•
Filing: 1987-02-19
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Granted: 1988-06-07
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Expires: 2007-02-19
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Abstract

Abstract Pharmaceutical compositions and methods of using same comprising a non-steroidal anti-inflammatory drug in combination with at least one other active component selected from an antihistamine, decongestant, cough suppressant (antitussive) or expectorant are provided for the relief of cough, cold and cold-like symptoms.

Inventors

  • 👤 Abraham Sunshine
  • 👤 Eugene M. Laska
  • 👤 Carole E. Siegel

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-04 11:28
CPC Classifications
A; A61; A61K; A61K45/00; A61K45/06; A61K31/00; A61K31/185; A61K31/19; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/455; A61K31/47; A61K31/485; A61K31/54; A61K31/60; A61P; A61P11/00; A61P11/10; A61P11/14; A61P25/00; A61P25/02; A61P25/04; A61P29/00; A61P43/00

Claims Analysis

Total Claims: 18
Claim 1
Independent Claim 70 words
A method for the treatment of cough, cold, cold-like and/or flu symptoms in a mammalian organism in need of such treatment, comprising administering to such organism a sympton relieving, sympathomimetically, analgesically and anti-inflammatorily effective amount of (i) at least one of the fenamic acid NSAIDs, mefenamic acid, meclofenamate, or pharmaceutically acceptable salt thereof, in combinatory immixture with (ii) at least one sympathomimetic decongestant or bronchodilator, or pharmaceutically acceptable salt thereof.
Claim 2
Independent Claim 70 words
A method for the treatment of cough, cold, cold-like and/or flu symptoms in a mammalian organism in need of such treatment, comprising administering to such organism a sympton relieving, sympathomimetically, analgesically and anti-inflammatorily effective amount of (i) at least one of the fenamic acid NSAIDs, mefenamic acid, meclofenamate, or pharmaceutically acceptable salt thereof, in combinatory immixture with (ii) at least one sympathomimetic decongestant or bronchodilator, or pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim 34 words
A method for the treatment of cough, cold, cold-like and/or flu symptoms in a mammalian organism in need of such treatment, comprising administering to such organism the pharmaceutical composition as defined by claim 1.
Claim 4
Dependent Claim 34 words
A method for the treatment of cough, cold, cold-like and/or flu symptoms in a mammalian organism in need of such treatment, comprising administering to such organism the pharmaceutical composition as defined by claim 2.
Claim 5
Dependent Claim 69 words
A pharmaceutical composition of matter for use in the treatment of cough, cold, cold-like and/or flu symptoms in a mammalian organism, said composition comprising a sympathomimetically, analgesically and anti-inflammatorily effective amount of (i) at least one of the fenamic acid NSAIDs, mefenamic acid, meclofenamate, or pharmaceutically acceptable salt thereof, in combinatory immixture with (ii) at least one of the sympathomimetic amines, pseudoephedrine, phenylpropanolamine, phenylephrine, or pharmaceutically acceptable salt thereof.
Claim 6
Dependent Claim 69 words
A pharmaceutical composition of matter for use in the treatment of cough, cold, cold-like and/or flu symptoms in a mammalian organism, said composition comprising a sympathomimetically, analgesically and anti-inflammatorily effective amount of (i) at least one of the fenamic acid NSAIDs, mefenamic acid, meclofenamate, or pharmaceutically acceptable salt thereof, in combinatory immixture with (ii) at least one of the sympathomimetic amines, pseudoephedrine, phenylpropanolamine, phenylephrine, or pharmaceutically acceptable salt thereof.
Claim 7
Dependent Claim 19 words
The pharmaceutical composition as defined by claim 4, said NSAID (i) comprising mefenamic acid or pharmaceutically acceptable salt thereof.
Claim 8
Dependent Claim 18 words
The pharmaceutical composition as defined by claim 4, said NSAID (i) comprising meclofenamate or pharmaceutically acceptable salt thereof.
Claim 9
Dependent Claim 17 words
The pharmaceutical composition as defined by claim 4, comprising at least 125 mg of said NSAID (i).
Claim 10
Dependent Claim 19 words
The pharmaceutical composition as defined by claim 7, comprising from 125 mg to 250 mg of said NSAID (i).
Claim 11
Dependent Claim 23 words
The pharmaceutical composition as defined by claim 4, comprising (ii) from 60 mg to 120 mg of pseudoephedrine or pharmaceutically acceptable salt thereof.
Claim 12
Dependent Claim 23 words
The pharmaceutical composition as defined by claim 4, comprising (ii) from 25 mg to 50 mg of phenylpropanolamine or pharmaceutically acceptable salt thereof.
Claim 13
Dependent Claim 23 words
The pharmaceutical composition as defined by claim 4, comprising (ii) from 5 mg to 25 mg of phenylephrine or pharmaceutically acceptable salt thereof.
Claim 14
Dependent Claim 16 words
The pharmaceutical composition as defined by claim 4, further comprising (iii) a pharmaceutically acceptable non-toxic carrier.
Claim 15
Dependent Claim 12 words
The pharmaceutical composition as defined by claim 4, in oral dosage form.
Claim 16
Dependent Claim 15 words
The pharmaceutical composition as defined by claim 13, said oral dosage form comprising a tablet.
Claim 17
Dependent Claim 15 words
The pharmaceutical composition as defined by claim 14, said oral dosage form comprising a capsule.
Claim 18
Dependent Claim 15 words
The pharmaceutical composition as defined by claim 14, said oral dosage form comprising an elixir.

References Cited (Backward Citations)

US4322427A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-06-07 1991-12-07 1992-06-07 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-06-07 1995-12-07 1996-06-07 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-06-07 1999-12-07 2000-06-07 $7700.00 Window Closed / Lapsed

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