Kidney preservation machine

Claim 2

Apparatus for maintaining extracorporeal organs in a viable state during transportation and storage comprising, in combination: a readily manually transportable insulated enclosure including separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interior of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein said thermoelectric means includes a cooling plate supported in an upwardly facing position on the baes portion, and means supporting the perfusate reservoir in direct heat transfer juxtaposition atop the cooling plate.

Claim 3

The invention defined by claim 1 characterized in that the perfusate pump is disposed on the base portion outside of said enclosure.

Claim 4

The invention defined by claim 1 wherein said control means includes alarm means connected to said sensing meeans for signalling variation of perfusate temperature or pressure beyond predetermined limits.

Claim 5

The invention defined by claim 1 wherein said control means includes means for setting temperature limits to include upper, lower and control set point.

Claim 6

The invention defined by claim 1 wherein said control means includes means for adjusting the perfusate flow rate and operable to disually display the same.

Claim 7

The invention defined by claim 1 wherein said control means includes display means for visually displaying temperature of the perfusate being pumped.

Claim 8

The invention defined by claim 1 wherein said control means includes display means for visually displaying pressure of the perfusate being pumped.

Claim 9

The invention defined by claim 1 wherein said control means includes alarm means for signalling variations of perfusate flow rate beyond predetermined limits.

Claim 10

The invention defined by claim 1 wherein said thermoelectric means comprise a plurality of Peltier effect modules disposed on the base, each such module having a cool side and a warm side, and means in the hollow base for transferring heat from the warm side of the modules to the exterior of the hollow base.

Claim 11

The invention defined by claim 1 wherein there is a heat sink cooling plate on said hollow base for heat transfer juxtapositioned against the reservoir and against said Peltier effect modules.

Claim 12

The invention defined by claim 1 wherein said control means includes alarm means connected to said sensing means for signalling variation of perfusate temperature, flow, pressure and supply voltage beyond predetermined limits.

Claim 13

Apparatus for maintaining extracoporeal organs in a viable state during transportation and storage comprising, in combination; a readily manually transportable insulated enclosure including a separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interior of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein said base portion includes a console portion disposed outside said enclosure including a pump control display and a temperature control display.

Claim 14

Apparatus for maintaining extracoporeal organs in a viable state during transportation and storage comprising, in combination; a readily manually transportable insulated enclosure including a separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interior of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein said base portion includes a console portion disposed outside said enclosure including a pump control display and a temperature control display.

Claim 15

Apparatus for maintaining extracorporeal organs in a viable state during transportation and storage comprising, in combination: a readily manually transportable insulated enclosure including separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interor of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein said perfusate reservoir includes a pair of individual reservoirs and said means for supporting an organ comprises means for supporting one organ above each reservoir, and said pump includes separate pumping chambers for each reservoir and organ, said chambers comprising flexible pump tubes for connection between the reservoir and the respective organ.

Claim 16

Apparatus for maintaining extracorporeal organs in a viable state during transportation and storage comprising, in combination: a readily manually transportable insulated enclosure including separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interor of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein said perfusate reservoir includes a pair of individual reservoirs and said means for supporting an organ comprises means for supporting one organ above each reservoir, and said pump includes separate pumping chambers for each reservoir and organ, said chambers comprising flexible pump tubes for connection between the reservoir and the respective organ.

Claim 17

Apparatus for maintaining extracorporeal organs in a viable state during transportation and storage comprising, in combination: a readily manually transportable insulated enclosure including separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interior of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein means are provided in the hollow base for connection to either a source of low voltage direct current or a source of 110 V alternating current and for converting the latter to a low voltage direct current for supplying the pump and thermoelectric means.

Claim 18

Apparatus for maintaining extracorporeal organs in a viable state during transportation and storage comprising, in combination: a readily manually transportable insulated enclosure including separable cover and base portions; means for releasably securing the base and cover portions together; a perfusate reservoir in the enclosure; thermoelectric means in the base portion for cooling the reservoir and interior of the enclosure; means in the enclosure for supporting an organ for perfusing; means in the enclosure for directing perfusate expelled from the organ to the perfusate reservoir; a perfusate pump on the base portion for fluid connection between the reservoir and an organ supported within the enclosure; control means including means for sensing the temperature and pressure of perfusate being pumped, said control means being connected to said pump and to said thermoelectric means for varying the operation of the pump and thermoelectric means to maintain the temperature and flow or pressure of the perfusate being pumped within predetermined limits; and wherein means are provided in the hollow base for connection to either a source of low voltage direct current or a source of 110 V alternating current and for converting the latter to a low voltage direct current for supplying the pump and thermoelectric means.