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US4745196A Expired / Lapsed US ⏱️ 0.0 years remaining

Orally active phosphonyl hydroxyacyl prolines

Assignee: ER Squibb and Sons LLC
•
Filing: 1986-01-06
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Granted: 1988-05-17
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Expires: 2006-01-06
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Abstract

Abstract This invention is directed to orally active antihypertensive agents of the formula <IMAGE> wherein R1 is certain alkyl or aralkyl groups.

Inventors

  • 👤 Donald S. Karanewsky
  • 👤 Edward W. Petrillo, Jr.

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-25 02:29
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/547; C07F9/553; C07F9/572; A; A61; A61P; A61P43/00; A61P9/00; A61P9/12

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 12 words
A compound of the formula ##STR25## or a pharmaceutically acceptable salt thereof.
Claim 2
Dependent Claim 12 words
A compound of the formula ##STR25## or a pharmaceutically acceptable salt thereof.
Claim 3
Dependent Claim 8 words
The compound of claim 1, (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline, dilithium salt.
Claim 4
Dependent Claim 6 words
The compound of claim 1, (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline.

References Cited (Backward Citations)

US4452791A Cited
EP0097534A2 Cited
US4452790A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-05-17 1991-11-16 1992-05-17 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-05-17 1995-11-16 1996-05-17 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-05-17 1999-11-16 2000-05-17 $7700.00 Window Closed / Lapsed

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