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US4743247A Expired / Lapsed US ⏱️ 0.0 years remaining

Process for manufacturing dosage form

Assignee: Alza Corp
•
Filing: 1986-03-31
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Granted: 1988-05-10
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Expires: 2006-03-31
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Abstract

Abstract A device is disclosed with an internal space for receiving a beneficial agent. The device comprises a wall surrounding a compartment provided with an internal space and a hydrogel. A passageway in the wall connects the exterior of the device with the internal space. The passageway is used for filling the space with a beneficial agent, and then for dispensing the beneficial agent from the device.

Inventors

  • 👤 Patrick S. Wong

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-28 01:00
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0002; A61K9/0004

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 81 words
An article of manufacture useful as a dosage form for dispensing a beneficial agent formulation, the article comprising: (a) a shaped wall comprising in at least a part a semipermeable composition permeable to the passage of an exterior fluid, the wall surrounding and forming: (b) a compartment comprising an internal empty space, a layer of a wax and a layer of a hydrogel; and, (c) means in the wall for communicating the exterior of the article of manufacture with the compartment.
Claim 2
Dependent Claim 81 words
An article of manufacture useful as a dosage form for dispensing a beneficial agent formulation, the article comprising: (a) a shaped wall comprising in at least a part a semipermeable composition permeable to the passage of an exterior fluid, the wall surrounding and forming: (b) a compartment comprising an internal empty space, a layer of a wax and a layer of a hydrogel; and, (c) means in the wall for communicating the exterior of the article of manufacture with the compartment.
Claim 3
Dependent Claim 75 words
An article of manufacture useful as a dosage form for dispensing a beneficial agent formulation, the article comprising: (a) shaped wall comprising in at least a part a semipermeable composition permeable to the passage of an exterior fluid, the wall surrounding and forming: (b) a compartment comprising a layer of wax and a layer of a hydrogel; and, (c) means in the wall for communicating the exterior of the article of manufacture with the compartment.
Claim 4
Dependent Claim 75 words
An article of manufacture useful as a dosage form for dispensing a beneficial agent formulation, the article comprising: (a) shaped wall comprising in at least a part a semipermeable composition permeable to the passage of an exterior fluid, the wall surrounding and forming: (b) a compartment comprising a layer of wax and a layer of a hydrogel; and, (c) means in the wall for communicating the exterior of the article of manufacture with the compartment.
Claim 5
Dependent Claim 87 words
A process for manufacturing a dispensing device provided with an internal empty space for receiving beneficial agent formulation, the process comprising: (a) forming a layer of wax; (b) surrounding the layer of wax with a wall comprising in at least a part a semipermeable composition; (c) forming at least one passageway in the wall connecting the exterior with the interior of the device; (d) heating the wax; and, (e) draining the wax through a passageway from the device, thereby providing an internal empty space in the device.
Claim 6
Dependent Claim 87 words
A process for manufacturing a dispensing device provided with an internal empty space for receiving beneficial agent formulation, the process comprising: (a) forming a layer of wax; (b) surrounding the layer of wax with a wall comprising in at least a part a semipermeable composition; (c) forming at least one passageway in the wall connecting the exterior with the interior of the device; (d) heating the wax; and, (e) draining the wax through a passageway from the device, thereby providing an internal empty space in the device.
Claim 7
Dependent Claim 107 words
A process for the manufacture of a dosage form provided with an internal space for receiving a beneficial agent formulation, the process comprising: (a) forming a layer of a hydrogel; (b) forming a layer of wax in contact with the hydrogel; (c) surrounding the layers with a wall comprising in at least a part a semipermeable composition; (d) forming at least one passageway in the wall connecting the exterior with the interior of the dosage form; (e) heating the dosage form to melt the wax; and, (f) draining the wax through a passageway from the dosage form to provide an internal empty space in the dosage form.
Claim 8
Dependent Claim 107 words
A process for the manufacture of a dosage form provided with an internal space for receiving a beneficial agent formulation, the process comprising: (a) forming a layer of a hydrogel; (b) forming a layer of wax in contact with the hydrogel; (c) surrounding the layers with a wall comprising in at least a part a semipermeable composition; (d) forming at least one passageway in the wall connecting the exterior with the interior of the dosage form; (e) heating the dosage form to melt the wax; and, (f) draining the wax through a passageway from the dosage form to provide an internal empty space in the dosage form.

References Cited (Backward Citations)

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US4361545A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-05-10 1991-11-09 1992-05-10 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-05-10 1995-11-09 1996-05-10 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-05-10 1999-11-09 2000-05-10 $7700.00 Window Closed / Lapsed

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