Derivatives of alpha-(2-oxo 2,4,5,6,7,7a-hexahydro thieno[3,2-c]5-pyridyl) phenyl acetic acid, and their use as platelet and thrombotic aggregation inhibitors

Claim 1

A compound of the formula ##STR26## in which Y represents hydroxyl (--OH): or Y represents (--OR) in which R is a linear or branched C 1 -C 4 alkyl radical or a benzyl or phenylethyl radical, or a phenyl- substituted benzyl of phenylethyl radical, or a dialkyl amino group of the formula: ##STR27## in which n represents a whole number from 0 to 4, R 1 and R 2 are each a C 1 -C 4 alkyl radical or Y represents an amino group of the formula ##STR28## in which R 3 and R 4 may be the same or different and are each hydrogen or a linear or branched C 1 -C 4 alkyl group, a phenyl, benzyl, phenylthyl, substituted benzyl or substituted phenylethyl group, a (3-pyridyl) methyl or (4-pyridyl) methyl group, or R 3 and R 4 from together with the nitrogn atom to which they are attached, a pyrrolidiono or morpholino group, these being unsubstituted or substituted by C 1 -C 4 alkyl radical, a phenyl radical, or a phenyl radical substituted by at least one member of the group consisting of halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, or trifluoromethyl; where X represent hydrogen, halogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, trifluoromethyl, nitro, cyano, carboxy or a C 1 -C 4 alkoxy carbonyl; and the acid addition salts with pharmaceutically acceptable inorganic and organic acids.