US4726381A
Expired / Lapsed
US
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Dialysis system and method
Assignee: Solutech Inc
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Filing: 1986-06-04
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Granted: 1988-02-23
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Expires: 2006-06-04
Abstract
Abstract An apparatus and a method of use for removing specified dialyzable components from a complex reference fluid such as, for example, blood. The invention includes a semi-permeable tubular dialysis membrane, which is inserted into the reference fluid. An equilibration fluid is injected into the tubular membrane and allowed to equilibrate with the outside reference fluid. The equilibrated fluid is then removed for analysis.
Inventors
- 👤 Jeffrey S. Jones
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 23:53
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/0002; A61B5/0031; A61B5/07; A61B5/145; A61B5/14525; A61B5/14528; A61B5/68; A61B5/6846; A61B5/6847; A61B5/686; B; B01; B01D; B01D61/00; B01D61/24; B01D61/28; G; G01; G01N; G01N33/00; G01N33/48; G01N33/483; G01N33/487; G01N33/49; G01N33/491
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
164 words
An apparatus for equilibrating dialyzable components from a complex fluid for analysis or for adding specified components to a fluid, comprising: (1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane; (2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and (3) fluid communication means adapted to pass a membrane solution to and from said body portion wherein said fluid communication means comprises a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other.
Claim 2
Independent Claim
164 words
An apparatus for equilibrating dialyzable components from a complex fluid for analysis or for adding specified components to a fluid, comprising: (1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane; (2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and (3) fluid communication means adapted to pass a membrane solution to and from said body portion wherein said fluid communication means comprises a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other.
Claim 3
Dependent Claim
18 words
The apparatus according to claim 1, wherein said second end of said tubular conduit includes a self-sealing membrane.
Claim 4
Dependent Claim
13 words
The apparatus according to claim 1, wherein said dialyzing membrane is gas permeable.
Claim 5
Dependent Claim
36 words
The apparatus according to claim 1, wherein said body portion is substantially of uniform cross-section and the permeability of said body portion extends along the length of said tubular membrane between its proximal and distal end.
Claim 6
Dependent Claim
24 words
The apparatus according to claim 1, wherein the tubular dialyzing membrane is an equilibration membrane which allows specified components to pass through said membrane.
Claim 7
Dependent Claim
28 words
The apparatus according to claim 1, wherein said tubular dialyzing membrane is selected from the group consisting of cellulose, dimethylsilicone, methyl-vinyl-polysiloxane, polycarbonate/silicone copolymers, expanded tetrafluoroethylene and expanded polypropylene.
Claim 8
Dependent Claim
42 words
The apparatus according to claim 1, wherein said apparatus adapted to be inserted percutaneously in a blood vessel approximately 3 mm in diameter and said body portion is approximately 2.2 mm in diameter, allowing approximately a 40% opening in the blood vessel.
Claim 9
Dependent Claim
28 words
The apparatus according to claim 1, wherein said lumen of said body portion is adapted to contain from about 0.2 milliliters to 4.0 milliliters of said membrane solution.
Claim 10
Dependent Claim
196 words
A dialysis system having a size and shape to fit within a blood vessel for equilibrating dialyzable components in a blood stream, said system comprising: (1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane, wherein said body portion is substantially of uniform cross-section and the permeability of said body portion extends along the length of said tubular membrane between its proximal and distal ends; (2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and (3) fluid communication means adapted to pass a membrane solution and from said body portion, said fluid communication means comprising a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other.
Claim 11
Dependent Claim
196 words
A dialysis system having a size and shape to fit within a blood vessel for equilibrating dialyzable components in a blood stream, said system comprising: (1) a body portion including a flexible, elongated tubular semi-permeable dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzable membrane, wherein said body portion is substantially of uniform cross-section and the permeability of said body portion extends along the length of said tubular membrane between its proximal and distal ends; (2) a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion; and (3) fluid communication means adapted to pass a membrane solution and from said body portion, said fluid communication means comprising a tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first and a second end, wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portion and said conduit communicate directly with each other.
Claim 12
Independent Claim
246 words
A method for equilibrating dialyzable components in a complex fluid for analysis comprising: (1) placing a dialysis apparatus into said fluid, said apparatus comprising a body portion including a flexible elongated tubular dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzing membrane, a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion, an elongated tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first end and a second end wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portions and said conduit communicate directly with each other, and said conduit being adapted to receive a means for injecting and withdrawing a membrane solution into said body portion lumen in such a manner that the distal portion of said injecting means is in adjacent and direct communication with said body portion lumen; (2) injecting a membrane solution through said conduit into said lumen of said tubular membrane, said membrane solution being adapted to equilibrate with said complex fluid, (3) maintaining said membrane solution in said lumen of said tubular membrane for a time sufficient to equilibrate said membrane solution; and (4) withdrawing said equilibrated membrane solution from said lumens for analysis.
Claim 13
Independent Claim
246 words
A method for equilibrating dialyzable components in a complex fluid for analysis comprising: (1) placing a dialysis apparatus into said fluid, said apparatus comprising a body portion including a flexible elongated tubular dialyzing membrane having a closed distal end and a proximal end, said body portion further including a single lumen within said tubular dialyzing membrane, a wire stylet within said lumen for maintaining the longitudinal integrity of said body portion, said wire stylet extending substantially parallel along the length of said body portion, an elongated tubular conduit having a lumen along the longitudinal axis of said conduit, said conduit having a first end and a second end wherein said first end of said conduit is attached to said proximal end of said body portion such that the lumens of each of said body portions and said conduit communicate directly with each other, and said conduit being adapted to receive a means for injecting and withdrawing a membrane solution into said body portion lumen in such a manner that the distal portion of said injecting means is in adjacent and direct communication with said body portion lumen; (2) injecting a membrane solution through said conduit into said lumen of said tubular membrane, said membrane solution being adapted to equilibrate with said complex fluid, (3) maintaining said membrane solution in said lumen of said tubular membrane for a time sufficient to equilibrate said membrane solution; and (4) withdrawing said equilibrated membrane solution from said lumens for analysis.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-02-22 | 1991-08-24 | 1992-02-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-02-22 | 1995-08-24 | 1996-02-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-02-22 | 1999-08-24 | 2000-02-23 | $7700.00 | Window Closed / Lapsed |