US4724238A
Expired / Lapsed
US
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Method of treating inflammatory diseases with labdan derivatives
Assignee: Hoechst AG
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Filing: 1986-04-03
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Granted: 1988-02-09
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Expires: 2006-04-03
Abstract
Abstract The present invention relates to a process for the isolation of labdan derivatives from the plant Coleus forskohlii, and their use as medicaments having anti-inflammatory and analgesic activity.
Inventors
- 👤 Alihussein N. Dohadwalla
- 👤 Sadashiv S. Mandrekar
- 👤 Nandkumar K. Dadkar
- 👤 Yatendra Khandelwal
- 👤 Richard H. Rupp
- 👤 Noel J. DE Souza
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 01:12
CPC Classifications
C; C07; C07D; C07D311/00; C07D311/02; C07D311/78; C07D311/92; A; A61; A61K; A61K31/00; A61K31/33; A61K31/335; A61K31/35; A61P; A61P25/00; A61P25/04; A61P29/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
86 words
A method of treating inflammatory diseases which comprises administering to a mammal in need of such treatment an effective amount of a compound of the formula III ##STR10## wherein R 1 is in the 1-position and represents H, OH, or --OCO--C 1 -C 3 -alkyl, R 2 is H or OH, R 3 is H, R 4 stands for --CHO, --CH═CH 2 , --CHOHCH 2 H or ##STR11## and X and Y stand for H or ##STR12## where R stands for C 1 -C 3 -alkyl.
Claim 2
Independent Claim
86 words
A method of treating inflammatory diseases which comprises administering to a mammal in need of such treatment an effective amount of a compound of the formula III ##STR10## wherein R 1 is in the 1-position and represents H, OH, or --OCO--C 1 -C 3 -alkyl, R 2 is H or OH, R 3 is H, R 4 stands for --CHO, --CH═CH 2 , --CHOHCH 2 H or ##STR11## and X and Y stand for H or ##STR12## where R stands for C 1 -C 3 -alkyl.
Claim 3
Dependent Claim
44 words
The method as defined in claim 1 wherein a compound of the formula III is administered wherein R 1 represents the 1-OH-group, R 2 represents OH, R 3 and X represent H, Y represents the residue ##STR13## and R 4 represents the vinyl group.
Claim 4
Dependent Claim
41 words
The method as defined in claim 1 wherein a compound of the formula III is administered where R 1 , R 2 , R 3 and X represents H, Y represents the group ##STR14## and R 4 represents the vinyl group.
Claim 5
Independent Claim
23 words
A method for treating pain wich comprises the administration to a host in need of such treatment a therapeutically effective amount of 1,9-dideoxyforskolin.
Claim 6
Independent Claim
23 words
A method for treating pain wich comprises the administration to a host in need of such treatment a therapeutically effective amount of 1,9-dideoxyforskolin.
References Cited (Backward Citations)
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Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1991-02-08 | 1991-08-10 | 1992-02-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1995-02-08 | 1995-08-10 | 1996-02-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1999-02-08 | 1999-08-10 | 2000-02-09 | $7700.00 | Window Closed / Lapsed |