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US4721730A Expired / Lapsed US ⏱️ 0.0 years remaining

Adsorbent for β2 -microglobulin and immunoglobulin L-chain

Assignee: Kanegafuchi Chemical Industry Co Ltd
•
Filing: 1987-05-29
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Granted: 1988-01-26
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Expires: 2007-05-29
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Abstract

Abstract An adsorbent for beta 2-microglobulin and immunoglobulin L-chain suitable for use in an extracorporeal circulation treatment, which comprises a porous water-insoluble carrier and a compound immobilized onto said carrier, said compound satisfying that the value of log P, in which P is a partition coefficient in an octanol-water system, is not less than 2.5. The adsorbent is inexpensive, and efficiently adsorb and remove beta 2-microglobulin and immunoglobulin L-chain contained in a body fluid.

Inventors

  • 👤 Shigeo Furuyoshi
  • 👤 Eiji Ogino
  • 👤 Nobutaka Tani

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-09 06:08
CPC Classifications
B; B01; B01J; B01J20/00; B01J20/28; B01J20/28014; B01J20/28047; B01J20/28054; B01J20/28057; B01J20/28078; B01J20/30; B01J20/3092; B01J20/32; B01J20/3202; B01J20/3206; B01J20/3208; B01J20/321; B01J20/3212; B01J20/3214; B01J20/3217; B01J20/3219; B01J20/3231; B01J20/3242; B01J20/3244; B01J20/3246; B01J20/3248; B01J20/3255; B01J2220/00; B01J2220/50; B01J2220/58

Claims Analysis

Total Claims: 4
Claim 1
Independent Claim 76 words
An adsorbent for β 2 -microglobulin and immunoglobulin L-chain suitable for use in an extracorporeal circulation treatment, which comprises a porous water-insoluble carrier, and carrier having molucular weight of the exclusion limit measured with a globular protein from 1×10 4 to 6×10 5 , and a compound immobilized onto said carrier, said compound satisfying that the value of log P, in which P is a partition coefficient in an octanol-water system, is not less than 2.5.
Claim 2
Dependent Claim 76 words
An adsorbent for β 2 -microglobulin and immunoglobulin L-chain suitable for use in an extracorporeal circulation treatment, which comprises a porous water-insoluble carrier, and carrier having molucular weight of the exclusion limit measured with a globular protein from 1×10 4 to 6×10 5 , and a compound immobilized onto said carrier, said compound satisfying that the value of log P, in which P is a partition coefficient in an octanol-water system, is not less than 2.5.
Claim 3
Dependent Claim 14 words
The adsorbent of claim 1, wherein said porous water-insoluble carrier is a hydrophilic carrier.
Claim 4
Dependent Claim 14 words
The adsorbent of claim 1, wherein said porous water-insoluble carrier is a hard carrier.

References Cited (Backward Citations)

US4411795A Cited
US4668706A Cited
US4654420A Cited
US4656261A Cited
US4678580A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-01-25 1991-07-27 1992-01-26 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-01-25 1995-07-27 1996-01-26 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-01-25 1999-07-27 2000-01-26 $7700.00 Window Closed / Lapsed

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