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US4718022A Expired / Lapsed US ⏱️ 0.0 years remaining

Dialysis machine which anticipates concentration changes

Assignee: Individual
•
Filing: 1985-02-21
•
Granted: 1988-01-05
•
Expires: 2005-02-21
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Abstract

Abstract A dialysis machine has control circuit which detects changes in input water temperature and compensates the water heater. The control circuit detects changes in the conductivity of the dialysate concentrate and compensates the concentrate pump. Changes in supply voltage are detected and the outputs of the several sensors and the inputs to the pumps and heater compensated. The control circuit periodically calibrates the blood leak detector. In each of the feedback loops which service the heater and each of the pumps, the control circuit varies both the loop response time and the loop gain to compensate for changes in the dialysate flow rate. The resolution of the D/A converters which drive the pumps are enhanced by the control circuit by time modulating the LSB of the respective digital drive value. If any of the several sensed operating conditions varies significantly from the expected value, the control circuit terminates dialysis.

Inventors

  • 👤 Michael J. Cochran

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 16:01
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1654; A61M1/1656; A61M1/166; A61M1/1664

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 227 words
In a dialysis machine for supplying dialysate to an artificial kidney at a selected flow rate, comprising: water supply means for supplying water at a water flow rate related to the selected flow rate; concentrate supply means for supplying dialysate concentrate at a rate proportional to a concentrate flow rate signal; mixing means for supplying the dialysate to the artificial kidney by mixing the water supplied by the water supply means with the concentrate supplied by the concentrate supply means; dialysate conductivity sensing means for providing a dialysate conductivity signal having a value proportional to the conductivity of the dialysate supplied to the artificial kidney by the mixing means; and concentrate flow rate control means for providing the concentrate flow rate signal to the concentrate supply means in proportion to a concentrate flow rate control signal the value of the concentrate flow rate control signal being selectively varied in response to changes in the value of the dialysate conductivity signal; the improvement comprising: concentrate conductivity sensing means for providing a concentrate conductivity signal having a value proportional to the conductivity of the concentrate supplied by the concentrate supply means; and conductivity compensation means for selectively varying the value of the dialysate conductivity signal provided to the concentrate flow rate control means by the dialysate conductivity sensing means in proportion to the value of the concentrate conductivity signal.
Claim 2
Dependent Claim 227 words
In a dialysis machine for supplying dialysate to an artificial kidney at a selected flow rate, comprising: water supply means for supplying water at a water flow rate related to the selected flow rate; concentrate supply means for supplying dialysate concentrate at a rate proportional to a concentrate flow rate signal; mixing means for supplying the dialysate to the artificial kidney by mixing the water supplied by the water supply means with the concentrate supplied by the concentrate supply means; dialysate conductivity sensing means for providing a dialysate conductivity signal having a value proportional to the conductivity of the dialysate supplied to the artificial kidney by the mixing means; and concentrate flow rate control means for providing the concentrate flow rate signal to the concentrate supply means in proportion to a concentrate flow rate control signal the value of the concentrate flow rate control signal being selectively varied in response to changes in the value of the dialysate conductivity signal; the improvement comprising: concentrate conductivity sensing means for providing a concentrate conductivity signal having a value proportional to the conductivity of the concentrate supplied by the concentrate supply means; and conductivity compensation means for selectively varying the value of the dialysate conductivity signal provided to the concentrate flow rate control means by the dialysate conductivity sensing means in proportion to the value of the concentrate conductivity signal.
Claim 3
Dependent Claim 75 words
The dialysis machine of claim 1 further comprising: dialysate temperature sensing means for providing a dialysate temperature signal having a value proportional to the temperature of the dialysate supplied by the mixing means to the artificial kidney; and dialysate temperature compensation means for selectively varying the value of the dialysate conductivity signal provided to the concentrate flowrate control means by the dialysate conductivity sensing means in proportion to the value of the dialysate temperature signal.
Claim 4
Dependent Claim 75 words
The dialysis machine of claim 2 further comprising: concentrate temperature sensing means for providing a concentrate temperature signal having a value proportional to the temperature of the concentrate supplied to the mixing means by the concentrate supply means; and concentrate temperature compensation means for selectively varying the value of the concentrate conductivity signal provided to the conductivity compensation means by the concentrate conductivity sensing means in proportion to the value of the concentrate temperature signal.
Claim 5
Dependent Claim 37 words
The dialysis machine of claim 3 further comprising: concentrate ratio control means for varying by a predetermined ratio the value of the concentrate conductivity signal provided to the conductivity compensation means by the concentrate conductivity sensing means.
Claim 6
Dependent Claim 82 words
The dialysis machine of claim 4 wherein the values of the dialysate conductivity signal and the concentrate conductivity signal are related to the value of a supply voltage, the dialysis machine further comprising: supply voltage sensing means for providing a voltage reference signal having a value proportional to the value of the supply voltage; and voltage compensation means for selectively varying the values of the dialysate conductivity signal and the concentrate conductivity signal in proportion to changes in the voltage reference signal.
Claim 7
Dependent Claim 74 words
The dialysis machine of claim 5 further comprising: performance estimating means for estimating the conductivity of the dialysate based upon the water flow rate and the concentrate flow rate; performance measuring means for measuring the conductivity of the dialysate based upon the value of the dialysate conductivity signal; and performance verification means for preventing the dialysis machine from supplying dialysate to the artificial kidney if the estimated conductivity differs significantly from the measured conductivity.
Claim 8
Dependent Claim 75 words
The dialysis machine of claim 1 further comprising: concentrate temperature sensing means for providing a concentrate temperature signal having a value proportional to the temperature of the concentrate supplied to the mixing means by the concentrate supply means; and concentrate temperature compensation means for selectively varying the value of the concentrate conductivity signal provided to the conductivity compensation means by the concentrate conductivity sensing means in proportion to the value of the concentrate temperature signal.
Claim 9
Dependent Claim 37 words
The dialysis machine of claim 7 further comprising: concentrate ratio control means for varying by a predetermined ratio the value of the concentrate conductivity signal provided to the conductivity compensation means by the concentrate conductivity sensing means.
Claim 10
Dependent Claim 82 words
The dialysis machine of claim 8 wherein the values of the dialysate conductivity signal and the concentrate conductivity signal are related to the value of a supply voltage, the dialysis machine further comprising: supply voltage sensing means for providing a voltage reference signal having a value proportional to the value of the supply voltage; and voltage compensation means for selectively varying the values of the dialysate conductivity signal and the concentrate conductivity signal in proportion to changes in the voltage reference signal.
Claim 11
Dependent Claim 74 words
The dialysis machine of claim 9 further comprising: performance estimating means for estimating the conductivity of the dialysate based upon the water flow rate and the concentrate flow rate; performance measuring means for measuring the conductivity of the dialysate based upon the value of the dialysate conductivity signal; and performance verification means for preventing the dialysis machine from supplying dialysate to the artificial kidney if the estimated conductivity differs significantly from the measured conductivity.
Claim 12
Dependent Claim 37 words
The dialysis machine of claim 1 further comprising: concentrate ratio control means for varying by a predetermined ratio the value of the concentrate conductivity signal provided to the conductivity compensation means by the concentrate conductivity sensing means.
Claim 13
Dependent Claim 82 words
The dialysis machine of claim 11 wherein the values of the dialysate conductivity signal and the concentrate conductivity signal are related to the value of a supply voltage, the dialysis machine further comprising: supply voltage sensing means for providing a voltage reference signal having a value proportional to the value of the supply voltage; and voltage compensation means for selectively varying the values of the dialysate conductivity signal and the concentrate conductivity signal in proportion to changes in the voltage reference signal.
Claim 14
Dependent Claim 74 words
The dialysis machine of claim 12 further comprising: performance estimating means for estimating the conductivity of the dialysate based upon the water flow rate and the concentrate flow rate; performance measuring means for measuring the conductivity of the dialysate based upon the value of the dialysate conductivity signal; and performance verification means for preventing the dialysis machine from supplying dialysate to the artificial kidney if the estimated conductivity differs significantly from the measured conductivity.
Claim 15
Dependent Claim 82 words
The dialysis machine of claim 1 wherein the values of the dialysate conductivity signal and the concentrate conductivity signal are related to the value of a supply voltage, the dialysis machine further comprising: supply voltage sensing means for providing a voltage reference signal having a value proportional to the value of the supply voltage; and voltage compensation means for selectively varying the values of the dialysate conductivity signal and the concentrate conductivity signal in proportion to changes in the voltage reference signal.
Claim 16
Dependent Claim 74 words
The dialysis machine of claim 14 further comprising: performance estimating means for estimating the conductivity of the dialysate based upon the water flow rate and the concentrate flow rate; performance measuring means for measuring the conductivity of the dialysate based upon the value of the dialysate conductivity signal; and performance verification means for preventing the dialysis machine from supplying dialysate to the artificial kidney if the estimated conductivity differs significantly from the measured conductivity.
Claim 17
Dependent Claim 74 words
The dialysis machine of claim 1 further comprising: performance estimating means for estimating the conductivity of the dialysate based upon the water flow rate and the concentrate flow rate; performance measuring means for measuring the conductivity of the dialysate based upon the value of the dialysate conductivity signal; and performance verification means for preventing the dialysis machine from supplying dialysate to the artificial kidney if the estimated conductivity differs significantly from the measured conductivity.

References Cited (Backward Citations)

US3878095A Cited
US4060485A Cited
US4366051A Cited
US4153554A Cited
US4138639A Cited
US4464172A Cited
US4601830A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1991-01-04 1991-07-06 1992-01-05 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1995-01-04 1995-07-06 1996-01-05 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1999-01-04 1999-07-06 2000-01-05 $7700.00 Window Closed / Lapsed

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