US4716179A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of non-irritating or slightly irritating and/or promoting diterpene alcohol and of derivatives thereof as antineoplastic preparations
Assignee: German Cancer Research Center
•
Filing: 1984-02-29
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Granted: 1987-12-29
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Expires: 2004-02-29
Abstract
Abstract The present invention is directed to a method of inhibiting the growth of cancer cells in a lower animal host through the use of phorbol.
Inventors
- 👤 Erich Hecker
- 👤 Hans Osswald
- 👤 Rainer Schmidt
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 16:54
CPC Classifications
C; C07; C07C; C07C49/00; C07C49/587; C07C49/703; C07C49/723; C07C49/727; A; A61; A61P; A61P31/00; A61P31/04; C07C49/743
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
29 words
The method of treating transplanted tumor-afflicted animal subjects which comprises administering to said subjects an anti-transplanted tumor effective amount of phorbol, said phorbol being incorporated in a carrier material.
Claim 2
Independent Claim
29 words
The method of treating transplanted tumor-afflicted animal subjects which comprises administering to said subjects an anti-transplanted tumor effective amount of phorbol, said phorbol being incorporated in a carrier material.
Claim 3
Dependent Claim
25 words
The method of claim 1, wherrein said carrier material is selected from the group consisting of polyethylene glycol, ethanol, sesame oil, cremophor and isopropyl myristate.
Claim 4
Independent Claim
34 words
The method of treating transplanted tumor-afflicted animal subjects, which comprises administering to said subjects phorbol in a weekly dose lower than 20% of the DL 50, said phorbol being incorporated in a carrier material.
Claim 5
Independent Claim
34 words
The method of treating transplanted tumor-afflicted animal subjects, which comprises administering to said subjects phorbol in a weekly dose lower than 20% of the DL 50, said phorbol being incorporated in a carrier material.
Claim 6
Dependent Claim
25 words
The method of claim 3, wherein said carrier material is selected from the group consisting of polyethylene glycol, ethanol, sesame oil, Cremophor and isopropyl myristate.
Claim 7
Independent Claim
40 words
A method for inhibiting the growth of cancer cells in a lower animal host which comprises the administration to the host of a cancer cell growth-inhibiting effective amount of a pharmaceutical composition which comprises phorbol and a pharmaceutically acceptable carrier.
Claim 8
Independent Claim
40 words
A method for inhibiting the growth of cancer cells in a lower animal host which comprises the administration to the host of a cancer cell growth-inhibiting effective amount of a pharmaceutical composition which comprises phorbol and a pharmaceutically acceptable carrier.
Claim 9
Dependent Claim
24 words
The method of claim 5 wherein said carrier is selected from the group consisting of polyethylene glycol, ethanol, sesame oil, cremophor and isopropyl myristate.
Claim 10
Dependent Claim
20 words
The method of claim 5 wherein a weekly dose of phorbol lower than 20% of the DL 50 is administered.
Claim 11
Dependent Claim
20 words
The method of claim 6 wherein a weekly dose of phorbol lower than 20% of the DL 50 is adminitered.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-12-28 | 1991-06-29 | 1991-12-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-12-28 | 1995-06-29 | 1995-12-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-12-28 | 1999-06-29 | 1999-12-29 | $7700.00 | Window Closed / Lapsed |