US4714673A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for measurement of concentration of substance
Assignee: Individual
•
Filing: 1984-09-10
•
Granted: 1987-12-22
•
Expires: 2004-09-10
Abstract
Abstract A method for measurement of the concentration of a substance diffusable through inert membranes has a measuring electrode of metal, an electrolyte chamber containing electrolyte, a lipophilous membrane partially covering the measuring electrode and located between the measuring electrode and the electrolyte, and a reference electrode, wherein the substance is H 2 O 2 , the combined membrane contains lipophilous ions and/or carrier-bound ions, the base membrane is proton impermeable, and the measuring electrode is formed as anode.
Inventors
- 👤 Manfred Kessler
- 👤 Jens Hoper
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-31 02:33
CPC Classifications
C; C12; C12M; C12M41/00; C12M41/30; C12M41/32; C12Q; C12Q1/00; C12Q1/001; C12Q1/005; C12Q1/006; Y; Y10; Y10S; Y10S435/00; Y10S435/817
Claims Analysis
Total Claims: 24
Claim 1
Independent Claim
116 words
A method for determining the concentration of H 2 O 2 by the steps of: providing a metal measuring electrode, a reference electrode, a proton impermeable lipophilious base membrane containing both a carrier and ions selected form the group consisting of lipophilious ions, carrier bound ions, and both lipophilious and carrier bound ions, and an electrolyte chamber containing an electrolyte; and locating said electrodes adjacent said chamber wherein said base membrane seals said measuring electrode from direct contact with said electrolyte; providing a polorization voltage across said electrodes; providing circuit indicating means operationaly connected to said electrodes; providing H 2 O 2 in said electrolyte; and determining H 2 O 2 concentration from said indicating means.
Claim 2
Independent Claim
116 words
A method for determining the concentration of H 2 O 2 by the steps of: providing a metal measuring electrode, a reference electrode, a proton impermeable lipophilious base membrane containing both a carrier and ions selected form the group consisting of lipophilious ions, carrier bound ions, and both lipophilious and carrier bound ions, and an electrolyte chamber containing an electrolyte; and locating said electrodes adjacent said chamber wherein said base membrane seals said measuring electrode from direct contact with said electrolyte; providing a polorization voltage across said electrodes; providing circuit indicating means operationaly connected to said electrodes; providing H 2 O 2 in said electrolyte; and determining H 2 O 2 concentration from said indicating means.
Claim 3
Dependent Claim
13 words
A method as defined in claim 1, wherein said ions provided are anions.
Claim 4
Dependent Claim
15 words
A method as defined in claim 1, wherein said carrier bound ions provided are cations.
Claim 5
Dependent Claim
16 words
A method as defined in claim 3, wherein said carrier bound ions provided are potassium ions.
Claim 6
Dependent Claim
13 words
A method as defined in claim 1, wherein said carrier provided is valinomycin.
Claim 7
Dependent Claim
22 words
A method as defined in claim 1, wherein said carrier provided is a cation carrier of high mobility and specific for protons.
Claim 8
Dependent Claim
13 words
A method as defined in claim 6, wherein said carrier provided is tri-ni-dodecylamine.
Claim 9
Dependent Claim
26 words
A method as defined in claim 1, wherein said voltage provided is by a polarization voltage source having a plus pole connected with said measuring electrode.
Claim 10
Dependent Claim
21 words
A method as defined in claim 1, and further providing a closure membrane arranged to close said electrolyte chamber from outside.
Claim 11
Dependent Claim
20 words
A method as defined in claim 9, wherein said closure membrane provided is permeable to H 2 O 2 .
Claim 12
Dependent Claim
42 words
A method as defined in claim 9, wherein said electrolyte chamber provided is also formed as a reaction chamber which contains an enzyme converting a substance diffusable through said closure membrane into said electrolyte with formation of H 2 O 2 .
Claim 13
Dependent Claim
16 words
A method as defined in claim 11, wherein said enzyme provided is in a water solution.
Claim 14
Dependent Claim
14 words
A method as defined in claim 11, wherein said enzyme provided is structure bound.
Claim 15
Dependent Claim
22 words
A method as defined in claim 11, wherein said closure membrane provided is permeable for small molecules and impermeable for large molecules.
Claim 16
Dependent Claim
23 words
A method as defined in claim 11, wherein said enzyme provided is glucose-oxidase, said closure membrane provided being permeable to glucose and glucon-acid-lactone.
Claim 17
Dependent Claim
23 words
A method as defined in claim 1, wherein said electrodes, said base membrane and said chamber provided, together form an integrated implantable unit.
Claim 18
Dependent Claim
31 words
A method as defined in claim 1, wherein said electrodes with said base membrane and said chamber are provided with a polarization voltage source and together form an integrated implantable unit.
Claim 19
Dependent Claim
27 words
A method as define in claim 1, wherein said reference electrode provided is composed of a noble metal and formed as a cathode covered with a membrane.
Claim 20
Dependent Claim
19 words
A method as defined in claim 18, wherein said membrane which covers said reference electrode comprises a proton carrier.
Claim 21
Dependent Claim
16 words
A method as define in claim 18, wherein said membrane covering said reference electrode comprises tri-n-dodecylamine.
Claim 22
Dependent Claim
16 words
A method as defined in claim 1, wherein said base membrane provided is composed of polyvinylchloride.
Claim 23
Dependent Claim
17 words
A method as defined in claim 1, wherein said base membrane provided is composed of silicon rubber.
Claim 24
Dependent Claim
18 words
A method as defined in claim 1, wherein said measuring electrode provided is composed of a noble metal.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-12-21 | 1991-06-22 | 1991-12-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-12-21 | 1995-06-22 | 1995-12-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-12-21 | 1999-06-22 | 1999-12-22 | $7700.00 | Window Closed / Lapsed |