Apparatus for extracorporeal treatment of blood

Claim 2

In a hemodialysis apparatus comprising a first chamber, a second chamber, a dialysis solution circuit, a blood circuit, means for preparing a fresh dialysis solution, and means for withdrawing ultrafiltrate from said dialysis circuit, said first chamber being separated by means of a membrane from said second chamber, said first chamber being connected into said dialysis solution circuit, and said second chamber being connected into said blood circuit, said blood circuit including a first blood side upstream of said second chamber and a second blood side downstream of said second chamber, the improvement comprising: a single sensor coupled between a single connection with a patient and a branch of said blood circuit into said first and second blood sides, said sensor alternately sensing inflowing blood quantities and outflowing blood quantities; an ultrafiltrate controller coupled to said sensor for receiving signals from said sensor and being operative during a first time interval to recognize a first output signal from said sensor representing outflowing blood quantities and being operative during a second time interval to recognize a second output signal from said sensor representing inflowing blood quantities and being operative after said first and second time intervals to compare said first output signal with said second output signal to determine the actual ultrafiltration rate; a control unit connected to said ultrafiltrate controller, said control unit having input means for inputting a predetermined ultrafiltration rate; and a dialysis solution pump coupled in said dialysis circuit downstream of said first chamber and operatively coupled to said ultrafiltrate controller for changing the pressure in said dialysis solution circuit, thereby changing the transmembrane pressure to cause the actual ultrafiltration rate to approach said predetermined ultrafiltration rate.

Claim 3

The apparatus according to claim 1, the improvement further comprising: a first blood pump connected in said first blood side and operatively coupled to said control unit; a second blood pump connected in said second blood side and operatively coupled to said control unit; and a pressure sensor connected to said first blood side downstream of said first blood pump and coupled to said control unit; said control unit being operative during said first time interval to activate said first blood pump and to deactivate said second blood pump and said control unit being operative during said second time interval to activate said third pump and to deactivate said second pump, and said control unit being operative to effectuate a switchover from said first time interval to said second time interval when said pressure sensor indicates to said control unit a pressure value which matches a predetermined excess pressure value.

Claim 4

In the apparatus of claim 2, the improvement further comprising: a supply line connected to said single connection with said patient; a discharge line connected to said single connection with said patient; a tube section connecting said discharge line and said supply line to said sensor; a supply line clip in said supply line operatively coupled to said control unit; a discharge line clip in said discharge line operatively coupled to said control unit; and a tube clip in said second blood side downstream of said second blood pump and operatively coupled to said control unit; said control unit being operative during said first time interval to open said discharge line clip, and to close said supply line clip and to close said tube clip, said control unit being operative during said second time interval to close said discharge clip and to open said supply line clip and to open said tube clip.

Claim 5

The apparatus according to claim 1 wherein said sensor includes a flow meter.

Claim 6

The apparatus according to claim 1 wherein said sensor includes an electromagnetic flow meter.

Claim 7

In the apparatus of claim 1, the improvement further including a drip chamber, a substitution fluid reservoir and a substitution fluid pump, said drip chamber being disposed in said second blood side and being operative to receive fluid from said second chamber, said substitution fluid reservoir being coupled to said drip chamber for providing substitution fluid into said drip chamber via said substitution fluid pump, said control unit being operatively coupled to said substitution fluid pump for coordinating the pumping rates of said substitution fluid pump and said dialysis solution pump.

Claim 8

In the apparatus according to claim 1, the improvement further comprising a drip chamber, a dialysis solution reservoir, and a filter, said drip chamber being coupled in said second blood side and said dialysis solution reservoir being connected to said drip chamber via said filter.

Claim 9

In a hemodialysis apparatus comprising a first chamber, a second chamber, a dialysis solution circuit, a blood circuit, means for preparing a fresh dialysis, solution, and means for withdrawing ultrafiltrate from said dialysis circuit, said first chamber being separated by means of a membrane from said second chamber, said first chamber being connected into said dialysis solution circuit, and said second chamber being connected into said blood circuit, said blood circuit including a first blood side upstream of said second chamber and a second blood side downstream of said second chamber, the improvement comprising: a single sensor coupled between a single connection with a patient and a branch of said blood circuit into said first and second blood sides, for alternately sensing inflowing blood quantities and outflowing blood quantities; an ultrafiltrate controller coupled to said sensor for receiving signals from said sensor and being operative during a first time interval to recognize a first output signal representing outflowing blood quantities and being operative during a second time interval to recognize a second output signal representing inflowing blood quantities and being operative to compare said first output signal with said second output signal to determine the actual ultrafiltation rate; a control unit connected to said ultrafiltrate controller, said control unit having input means for inputting a desired ultrafiltration rate; a first pump connected in said first blood side and operatively coupled to said control unit; a second pump connected in said second blood side and operatively coupled to said control unit; and a pressure sensor connected in said first blood side downstream of said first pump and coupled to said control unit; said control unit being operative during said first time interval to activate said first pump and to deactivate said second pump and being operative during said second time interval to deactivate said first pump and to activate said second pump, said control unit being operative to effectuate a switchover from said first time interval to said second time interval when said pressure sensor indicates to said control unit a pressure value which matches an excess pressure value, said control unit being further operative to determine said excess pressure value by comparing said actual ultrafiltration rate and said desired ultrafiltration rate.

Claim 10

In a hemodialysis apparatus comprising a first chamber, a second chamber, a dialysis solution circuit, a blood circuit, means for preparing a fresh dialysis, solution, and means for withdrawing ultrafiltrate from said dialysis circuit, said first chamber being separated by means of a membrane from said second chamber, said first chamber being connected into said dialysis solution circuit, and said second chamber being connected into said blood circuit, said blood circuit including a first blood side upstream of said second chamber and a second blood side downstream of said second chamber, the improvement comprising: a single sensor coupled between a single connection with a patient and a branch of said blood circuit into said first and second blood sides, for alternately sensing inflowing blood quantities and outflowing blood quantities; an ultrafiltrate controller coupled to said sensor for receiving signals from said sensor and being operative during a first time interval to recognize a first output signal representing outflowing blood quantities and being operative during a second time interval to recognize a second output signal representing inflowing blood quantities and being operative to compare said first output signal with said second output signal to determine the actual ultrafiltation rate; a control unit connected to said ultrafiltrate controller, said control unit having input means for inputting a desired ultrafiltration rate; a first pump connected in said first blood side and operatively coupled to said control unit; a second pump connected in said second blood side and operatively coupled to said control unit; and a pressure sensor connected in said first blood side downstream of said first pump and coupled to said control unit; said control unit being operative during said first time interval to activate said first pump and to deactivate said second pump and being operative during said second time interval to deactivate said first pump and to activate said second pump, said control unit being operative to effectuate a switchover from said first time interval to said second time interval when said pressure sensor indicates to said control unit a pressure value which matches an excess pressure value, said control unit being further operative to determine said excess pressure value by comparing said actual ultrafiltration rate and said desired ultrafiltration rate.

Claim 11

In the apparatus of claim 8, the improvement further comprising: a supply line connected to said single connection with said patient; a discharge line connected to said single connection with said patient; a tube section connecting said discharge line and said supply line to said sensor; a supply line clip in said supply line operatively coupled to said control unit; a discharge line clip in said discharge line operatively coupled to said control unit; and a tube clip in said second blood side downstream of said second pump and operatively coupled to said control unit; said control unit being operative during said first time interval to open said discharge clip, and to close said supply line clip and to close said tube clip, said control unit being operative during said second time interval to close said discharge clip and to open said supply line clip and to open said tube clip.

Claim 12

The apparatus according to claim 8 wherein said sensor includes a flow meter.

Claim 13

The apparatus according to claim 8 wherein said sensor includes an electromagnetic flow meter.

Claim 14

In the apparatus of claim 8, the improvement further including a drip chamber, a substitution fluid reservoir and a substitution fluid pump, said drip chamber being disposed in said second blood side and being operative to receive fluid from said second chamber, said substitution fluid reservoir being coupled to said drip chamber for providing substitution fluid into said drip chamber via said substitution fluid pump, said control unit being operatively coupled to said substitution fluid pump for controlling the pumping rate of said substitution fluid pump.

Claim 15

In the apparatus according to claim 8, the improvement further comprising a drip chamber, a dialysis solution reservoir, and a filter, said drip chamber being coupled in said second blood side and said dialysis solution being connected to said drip chamber via said filter.