US4707469A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Gangliosides mixture, useful as a therapeutical tool for eliminating painful effects or peripheral neuropathies
Assignee: Fidia SpA
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Filing: 1985-06-13
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Granted: 1987-11-17
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Expires: 2005-06-13
Abstract
Abstract A ganglioside mixture, comprised of the gangliosides GM1, GD1a, GD1b and GT1b, has been found to possess significant analgesic or pain relieving activity. The mixture is, therefore, useful for treating pain due to various peripheral neuropathies and the mixture is more effective than the individual gangliosides which comprise the mixture.
Inventors
- 👤 Francesco Della Valle
- 👤 Aurelio Romeo
- 👤 Silvana Lorenzi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-26 17:20
CPC Classifications
C; C07; C07H; C07H15/00; C07H15/02; C07H15/04; C07H15/10; A; A61; A61K; A61K31/00; A61K31/70; A61P; A61P25/00; A61P25/02; A61P25/04
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
43 words
A method for treating pain comprising administering to a host in pain a composition comprising an effective pain relieving amount of at least one ganglioside selected from the group consisting of GM 1 , GD 1a , GD 1b and GT 1b .
Claim 2
Independent Claim
43 words
A method for treating pain comprising administering to a host in pain a composition comprising an effective pain relieving amount of at least one ganglioside selected from the group consisting of GM 1 , GD 1a , GD 1b and GT 1b .
Claim 3
Dependent Claim
44 words
A method as in claim 1, wherein said composition comprises by weight, about 19 to 23 percent GM 1 , about 36 to 44 percent GD 1a , about 14 to 18 percent GD 1b and about 17 to 21 percent GT 1b .
Claim 4
Dependent Claim
36 words
A method as in claim 2, wherein said composition comprises, by weight, about 21 percent GM 1 , about 40 percent GD 1a , about 16 percent GD 1b and about 19 percent GT 1b .
Claim 5
Dependent Claim
16 words
A method as in claim 1, wherein said composition comprises at least two of said gangliosides.
Claim 6
Dependent Claim
16 words
A method as in claim 1, wherein said composition comprises at least three of said gangliosides.
Claim 7
Independent Claim
47 words
A method for treating pain due to peripheral neuropathies comprising administering to a host in pain a composition comprising an effective pain relieving amount of at least one ganglioside selected from the group consisting of GM 1 , GD 1a , GD 1b and GT 1b .
Claim 8
Independent Claim
47 words
A method for treating pain due to peripheral neuropathies comprising administering to a host in pain a composition comprising an effective pain relieving amount of at least one ganglioside selected from the group consisting of GM 1 , GD 1a , GD 1b and GT 1b .
Claim 9
Dependent Claim
45 words
A method as in claim 6, wherein said composition comprises, by weight, about 19 to 23 percent GM 1 , about 36 to 44 percent GD 1a , about 14 to 18 percent GD 1b , and about 17 to 21 percent GT 1b .
Claim 10
Dependent Claim
36 words
A method as in claim 6, wherein said composition comprises, by weight, about 21 percent GM 1 , about 40 percent GD 1a , about 16 percent GD 1b and about 19 percent GT 1b .
Claim 11
Dependent Claim
16 words
A method as in claim 6, wherein said composition comprises at least two of said gangliosides.
Claim 12
Dependent Claim
16 words
A method as in claim 6, wherein said composition comprises at least two of said gangliosides.
References Cited (Backward Citations)
EP0145209A2
Cited
EP0167449A2
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-11-16 | 1991-05-18 | 1991-11-17 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-11-16 | 1995-05-18 | 1995-11-17 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-11-16 | 1999-05-18 | 1999-11-17 | $7700.00 | Window Closed / Lapsed |