Phosphate glass ceramic for biological and medical applications

Claim 2

A biologically active phosphate glass ceramic for application as hard tissue or bone replacement or implant material which comprises a phosphate glass ceramic consisting essentially of ______________________________________ Al.sub.2 O.sub.3 3-21% by mass, CaO 8-26% by mass, R.sub.2 O [more than 10% and up to] 12-25% by mass, P.sub.2 O.sub.5 43-58% by mass, ______________________________________ wherein the 12-25% by mass R 2 O is selected from the group consisting of 12% to 25% by mass of Na 2 O, 12% to 18% by mass of K 2 O, and 12% to 25% Na 2 O and K 2 O together wherein the K 2 O content does not exceed 18% by mass and containing in addition to the glass phase the main crystal phases apatite and aluminiumorthophosphate of at least one of the tridymite form and the berlinite form, said biologically active phosphate glass ceramic having adjustable biologically active characteristics and being capable of being utilized for biological applications as a compact material, as a thin layer, or granulated form, said biologically active phosphate glass ceramic having a SiO 2 content no greater than 7% by mass, and having good biological compatibility with hard tissue or bone, so that said biologically active phosphate glass ceramic, when implanted, is capable of an optimal union, free of connecting tissues, between bone or hard tissue and said phosphate glass ceramic.

Claim 3

A bone cement for biological application comprising a mixture of biologically active phosphate glass ceramic of claim 1 and polyurethanes.

Claim 4

The biologically active phosphate glass ceramic of claim 1, in which the apatite comprises apatite fluoride.

Claim 5

The biologically active phosphate glass ceramic of claim 1, in which the apatite comprises hydroxylapatite.

Claim 6

The biologically active phosphate glass ceramic of claim 1, in which the apatite comprises mixed fluorine-hydroxylapatite.

Claim 7

The biologically active phosphate glass ceramic of claim 1, in which the apatite phase contains minor proportions of iron ions and/or magnesium ions and/or sodium ions and/or potassium ions.

Claim 8

A bone or hard tissue implant or substitute or bone cement, comprising a biologically active phosphate glass ceramic of claim 1.

Claim 9

a biologically active phosphate glass ceramic for application as hard tissue or bone replacement or implant material which comprises a phosphate glass ceramic consisting essentially of ______________________________________ Al.sub.2 O.sub.3 3-21% by mass, CaO 8-26% by mass, R.sub.2 O 12-25% by mass, P.sub.2 O.sub.5 43-58% by mass, TiO.sub.2 0-10% by mass, F.sup.- 0-7% by mass, FeO 0-6% by mass, Fe.sub.2 O.sub.3 0-5% by mass, MgO 0-6% by mass, ______________________________________ wherein the 12-25% by mass R 2 O is selected from the group consisting of 12% to 25% by mass of Na 2 O, 12% to 18% by mass of K 2 O, and 12% to 25% Na 2 O and K 2 O together wherein the K 2 O content does not exceed 18% by mass and containing in addition to the glass phase the main crystal phases apatite and aluminiumorthophosphate of at least one of the tridymite form and the berlinite form, said biologically active phosphate glass ceramic having adjustable biologically active characteristics and being capable of being utilized for biological applications as a compact material, as a thin layer, or in granulated form, said biologically active phosphate glass ceramic having a SiO 2 content no greater than 7% by mass, and having good biological compatibility with hard tissue or bone, so that said biologically active phosphate glass ceramic, when implanted, is capable of an optimal union, free of connecting tissues, between bone or hard tissue and said phosphate glass ceramic.

Claim 10

a biologically active phosphate glass ceramic for application as hard tissue or bone replacement or implant material which comprises a phosphate glass ceramic consisting essentially of ______________________________________ Al.sub.2 O.sub.3 3-21% by mass, CaO 8-26% by mass, R.sub.2 O 12-25% by mass, P.sub.2 O.sub.5 43-58% by mass, TiO.sub.2 0-10% by mass, F.sup.- 0-7% by mass, FeO 0-6% by mass, Fe.sub.2 O.sub.3 0-5% by mass, MgO 0-6% by mass, ______________________________________ wherein the 12-25% by mass R 2 O is selected from the group consisting of 12% to 25% by mass of Na 2 O, 12% to 18% by mass of K 2 O, and 12% to 25% Na 2 O and K 2 O together wherein the K 2 O content does not exceed 18% by mass and containing in addition to the glass phase the main crystal phases apatite and aluminiumorthophosphate of at least one of the tridymite form and the berlinite form, said biologically active phosphate glass ceramic having adjustable biologically active characteristics and being capable of being utilized for biological applications as a compact material, as a thin layer, or in granulated form, said biologically active phosphate glass ceramic having a SiO 2 content no greater than 7% by mass, and having good biological compatibility with hard tissue or bone, so that said biologically active phosphate glass ceramic, when implanted, is capable of an optimal union, free of connecting tissues, between bone or hard tissue and said phosphate glass ceramic.

Claim 11

A bone or hard tissue implant or substitute or bone content, comprising a biologically active phosphate glass ceramic of claim 8.

Claim 12

A bone cement for biological applications comprising a mixture of biologically active phosphate glass ceramic of claim 8 and polyurethane.

Claim 13

The biologically active phosphate glass ceramic of claim 8, in which the apatite comprises apatite fluoride.

Claim 14

The biologically active phosphate glass ceramic of claim 8, in which the apatite comprises hydroxylapatite.

Claim 15

The biologically active phosphate glass ceramic of claim 8, in which the apatite comprises mixed fluorine hydroxylapatite.

Claim 16

The biologically active phosphate glass ceramic of claim 8, in which the apatite phase contains minor proportions of at least one of iron ions, magnesium ions, sodium ions and potassium ions.