US4698101A
Expired / Lapsed
US
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Binder-diluent composition and method
Assignee: Danisco Sweeteners Oy
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Filing: 1985-03-06
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Granted: 1987-10-06
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Expires: 2005-03-06
Abstract
Abstract A binder-diluent for direct compression tableting based on pulverized crystalline fructose is prepared by granulating the fructose with a small amount of a disaccharide syrup such as maltose syrup.
Inventors
- 👤 Juha A. Koivurinta
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-07 18:38
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/20; A61K9/2004; A61K9/2013; A61K9/2018
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
66 words
A fructose-based dry binder-diluent for use in making direct compression tablets comprising a plurality of compressible free-flowing granules having a mean particle size in the range of about 0.15-0.60 mm, the granules having been formed by agglomeration of pulverized crystalline fructose with a maltose-containing syrup, followed by drying, and the granules containing by weight about 80-98% of fructose, about 2-20% disaccharide and up to 1.0% water.
Claim 2
Dependent Claim
66 words
A fructose-based dry binder-diluent for use in making direct compression tablets comprising a plurality of compressible free-flowing granules having a mean particle size in the range of about 0.15-0.60 mm, the granules having been formed by agglomeration of pulverized crystalline fructose with a maltose-containing syrup, followed by drying, and the granules containing by weight about 80-98% of fructose, about 2-20% disaccharide and up to 1.0% water.
Claim 3
Dependent Claim
35 words
The product of claim 1 wherein fructose is present at a level of about 89-97%, maltose is present at a level in the range of about 3-6% the percentages being by weight of the binder-diluent.
Claim 4
Dependent Claim
31 words
The product of claim 1 wherein said maltose containing syrup contains other saccharides which are present at a level up to about 8%, said percentage being by weight of the binder-diluent.
Claim 5
Dependent Claim
18 words
The product of claim 1, further comprising a lubricant suitable for use in a direct compression tableting process.
Claim 6
Dependent Claim
11 words
The product of claim 4, wherein the lubricant is magnesium stearate.
Claim 7
Dependent Claim
70 words
A fructose-based dry binder-diluent for use in making direct compression tablets comprising a plurality of compressible free-flowing granules of mean particle size in the range of about 0.15-0.60 mm, the granules having been formed by agitation of pulverized, crystalline fructose while adding thereto a maltose-containing syrup in finely divided form, followed by drying, the granules containing, by weight, about 80-98% of fructose, about 2-20% maltose and up to 1.0% water.
Claim 8
Dependent Claim
70 words
A fructose-based dry binder-diluent for use in making direct compression tablets comprising a plurality of compressible free-flowing granules of mean particle size in the range of about 0.15-0.60 mm, the granules having been formed by agitation of pulverized, crystalline fructose while adding thereto a maltose-containing syrup in finely divided form, followed by drying, the granules containing, by weight, about 80-98% of fructose, about 2-20% maltose and up to 1.0% water.
Claim 9
Dependent Claim
36 words
The product of claim 6 wherein fructose is present at a level of about 89-97%, the maltose is present at a level in the range of about 3-6% the percentages being by weight of the binder-diluent.
Claim 10
Dependent Claim
31 words
The product of claim 6 wherein said maltose containing syrup contains other saccharides which are present at a level up to about 8%, said percentage being by weight of the binder-diluent.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1990-10-05 | 1991-04-06 | 1991-10-06 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1994-10-05 | 1995-04-06 | 1995-10-06 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1998-10-05 | 1999-04-06 | 1999-10-06 | $7700.00 | Window Closed / Lapsed |